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Companion diagnostic drugs topic template

Revised: 14 May 2020
Copyright: 2020, PathologyOutlines.com, Inc.

    Example of well written Companion diagnostic drugs topic: Trastuzumab

    For ease of use, we put topic headings in the same order. Please put some text under each heading, but do not include obvious or repetitive information. If you think there is nothing to add, please write "not relevant to this topic", "repetitive with __ heading" or "unknown at this time" [i.e. if etiology is not known]. Do not delete any topic headings.


    Author 1

    Author name with degrees: ___________________________________________

    Author rank (M.D. candidate / Resident / Fellow / Instructor / Assistant, Associate or Full Professor): ___________________________________________

    Author leadership roles (maximum of 2) (ex: Director of Surgical Pathology, Vice Chair of Anatomic Pathology, Director of Cytopathology): ___________________________________________

    Author institution name: ___________________________________________

    Author institution city, state, zip code and country: ___________________________________________

    Author email address: ___________________________________________


    Author 2

    Author name with degrees: ___________________________________________

    Author rank (Assistant, Associate or Full Professor): ___________________________________________

    Author leadership roles (maximum of 2) (ex: Director of Surgical Pathology, Vice Chair of Anatomic Pathology, Director of Cytopathology): ___________________________________________

    Author institution name: ___________________________________________

    Author institution city, state, zip code and country: ___________________________________________

    Author email address: ___________________________________________



    Chapter name: Companion diagnostic testing

    Section and subsection (in the Table of Contents): ___________________________________________

    Topic name:___________________________________________



    Definition / general
    A 1 - 2 sentence summary of the topic.

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    Trade name
    The brand name of the drug.

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    Indications
    Any symptoms or diseases that may be treated by this drug.

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    Pathophysiology
    Step by step details of the drug discussed in this topic in relationship to the tumor.

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    Diagrams
    Those that don't automatically fit in another section. Provide caption and figure legend.


    Clinical information
    Anything clinical not included above or below. Includes associations with other conditions.

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    Uses by pathologists
    What is the companion diagnostic marker and testing modality that is used by pathologists? Link to the appropriate topic in the Stains & molecular markers chapter.

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    Side effects
    List any side effects pathologists should be aware of.

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    Drug administration
    How is the drug administered? Include timing, duration and dosing.

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    Molecular theory
    Description of DNA / RNA findings not discussed above based on testing via sequencing, PCR, FISH, CISH, ISH, cytogenetics, etc.

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    Additional references
    General references for this topic not included above.

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    Board Review Question(s)
    Prepare 2 board review style questions that highlight important content from this topic. These are not actual questions from the Pathology boards but review questions written in a similar format. The questions should test basic, essential diagnostic concepts that all pathologists should know rather than minor details. The topic needs to contain all information relevant to correct and incorrect answers. Questions should be multiple choice, such as "Which of the following is true about XXX tumor/disease?" Do not use the format "Which of the following is false?" Questions should have only one answer. Do not use responses "all of the above", "none of the above", "A and C", etc. This question will be part of our Board Review page so the reader will not know the topic with which it is associated. Therefore you must make the organ clear in the question and the diagnosis clear in the answer. Click here for examples.


    Board Review Answer(s)
    Answers to the Question(s) above, sorted alphabetically by the first letter in the answer.