Breast-nonmalignant

Authors: Jaya Ruth Asirvatham, M.D., Belinda Lategan, M.D., Hind Nassar, M.D. (see Authors page)

Editor: Julie M. Jorns, M.D.

Revised: 21 August 2015, last major update IN PROGRESS

Copyright: (c) 2001-2015, PathologyOutlines.com, Inc.

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Table of Contents

General: primary referencesWHO classificationembryologyneonatalthelarcheanatomyhistologypregnancy/lactationpubertal macromastia

Congenital anomalies: amastia/aplasia/hypoplasiaathelianipple inversionsupernumerary/accessory glandular tissue

Procedures: biopsy marking devicescautery artifactcore biopsycytologyMRI directedopen biopsy/frozen sectionreduction mammoplasty

Inflammatory / infectious: acute mastitis/abscesschronic inflammationduct ectasiafat necrosisforeign body reactionfungigiant cell arteritisgranulomatous mastitishemorrhagic necrosisinfarctlupus mastitislymphocytic mastitisMondor diseasenephrogenic systemic fibrosisossificationplasma cell mastitispolyarteritis nodosareactive spindle cell nodulesarcoidosissclerosing mastitissilicone implants-breastsilicone implants-axillatuberculosis

Parasites: cysticercosisechinococcal cystfilariasismyiasissparganosis

Fibrocystic disease: generalapocrine metaplasiacollagenous spherulosiscolumnar cell lesioncystic hypersecretory hyperplasiacystsepithelial ductal hyperplasiafibroadenomatoid changefibrosismicrocalcificationspseudolactational hyperplasiaradial scar

Adenosis: generaladenomyoepithelialapocrineblunt ductmicroglandularsclerosingtubular

Benign tumors / changes: adenomyoepitheliomaamyloid tumorangiolipomaapocrine adenomaatypical or benign vascular proliferations post-radiationbenign stromal spindle cell tumorsCarney syndromechondrolipomaclear cell "sugar" tumorcylindromaductal adenomaeccrine spiradenomafibroadenomafibroadenoma-cellularfibromatosisgalactocelegranular cell tumorgynecomastia-likehamartomahemangiomahemangiopericytomainflammatory myofibroblastic tumorjuvenile xanthogranulomalactating adenomaleiomyomalipomalymphangiomamucocelemyoepitheliomamyofibroblastomanipple adenoma/florid papillomatosisnodular mucinosispapillomaphyllodes-generalphyllodes-benignphyllodes-borderlinephyllodes-malignantpleomorphic adenomapseudoangiomatous stromal hyperplasia (PASH)sclerosing lobular hyperplasiaspindle cell lipomasubareolar sclerosing duct hyperplasiasyringomatous adenoma of nippletubular adenoma

Atypical hyperplasia: flat epithelial atypiaatypical ductal hyperplasia (ADH)atypical lobular hyperplasia (ALH)


Index (Alphabetical Table of Contents):

A-E: acute mastitis/abscessadenomyoepithelial adenosisadenomyoepitheliomaadenosis - generalamastia/aplasia/hypoplasiaamyloid tumoranatomyangiolipomaapocrine adenomaapocrine adenosisapocrine metaplasiaatheliaatypical ductal hyperplasia (ADH)atypical lobular hyperplasia (ALH)atypical or benign vascular proliferations post-radiationbenign stromal spindle cell tumorsbiopsy marking devicesblunt duct adenosisCarney syndromecautery artifactchondrolipomachronic inflammationclear cell "sugar" tumorcollagenous spherulosiscolumnar cell lesioncore biopsycylindromacystic hypersecretory hyperplasiacysticercosiscystscytologyduct ectasiaductal adenomaeccrine spiradenomaechinococcal cystembryologyepithelial ductal hyperplasia

F-N: fat necrosisfibroadenoma-cellularfibroadenomafibroadenomatoid changeFibrocystic disease - generalfibromatosisfibrosisfilariasisflat epithelial atypiaforeign body reactionfungigalactocelegiant cell arteritisgranular cell tumorgranulomatous mastitisgynecomastia-likehamartomahemangiomahemangiopericytomahemorrhagic necrosishistologyinfarctinflammatory myofibroblastic tumorjuvenile xanthogranulomalactating adenomaleiomyomalipomalupus mastitislymphangiomalymphocytic mastitismicrocalcificationsmicroglandular adenosisMondor diseaseMRI directed excisionmucocelemyiasismyoepitheliomamyofibroblastomaneonatal breastnephrogenic systemic fibrosisnipple adenoma/florid papillomatosisnipple inversionnodular mucinosis

O-Z: open biopsy/frozen sectionossificationpapillomaphyllodes-generalphyllodes-benignphyllodes-borderlinephyllodes-malignantplasma cell mastitispleomorphic adenomapolyarteritis nodosapregnancy/lactationprimary referencespseudoangiomatous stromal hyperplasia (PASH)pseudolactational hyperplasiapubertal macromastiaradial scarreactive spindle cell nodulereduction mammoplastysarcoidosissclerosing adenosissclerosing lobular hyperplasiasclerosing mastitissilicone implants-axillasilicone implants-breastsparganosisspindle cell lipomasubareolar sclerosing duct hyperplasiasupernumerary/accessory glandular tissuesyringomatous adenoma of nipplethelarchetuberculosistubular adenomatubular adenosisWHO classification


See also Breast-malignant chapter (DCIS, invasive carcinoma, other malignancies, miscellaneous, children, males)


Primary references:
Rosen: Tumors of the Mammary Gland (AFIP Fascicle, 3rd series, volume 7)
Tavassoli: Tumours of the Breast and Female Genital Organs (WHO, 2003)
Tavassoli: Tumors of the Mammary Gland (AFIP Fascicle, 4th series, volume 10); 2009

Websites: Digital Atlas of Breast Pathology, National Institutes of Health, Online Management of Breast Diseases, PathoPic

Virtual slides: University of Iowa, USCAP, vSlides


Recent Breast pathology books

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Dabbs: 2012

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Mohsin: 2011

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