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Breast-malignant, males, children

 

Author: Nat Pernick, M.D, PathologyOutlines.com, Inc.

Reviewer: Daniel Visscher, M.D., University of Michigan Hospitals, February 2009 (see Reviewers page)

Revised: 8 October 2009

Last major update: October 2009 - in progress

Copyright: (c) 2002-2009, PathologyOutlines.com, Inc.

Printer Friendly Versions: HTML, PDF - under construction

 

Table of Contents

Primary references

 

In situ carcinoma: DCIS-general, DCIS variants: apocrinebasal-likeclingingcomedocribriformcystic hypersecretorymicropapillarymucinousneuroendocrinepapillarysignet ring cellsolidsolid papillaryspindle cellsquamous cell / Bowen’s disease //;  LCIS-classicLCIS-pleomorphicductal intraepithelial neoplasia (DIN)mammary intraepithelial neoplasiaPaget’s disease, anaplastic Paget’s

 

Breast cancer: generalaxillary nodesEGFR,  HER2histologic gradinghormone receptorsmicroinvasivepregnancy

prognostic factors: generalangiolymphatic invasionfibrotic focusmultigene products

risk factorssentinel nodes,  spread/metastasessuspicious,  WHO classification  

 

Carcinoma subtypes: generalacinic celladenoid cysticadenosquamousapocrinebasal cell-nipplebasal-likeBRCA1BRCA2central acellularcribriformcystic hypersecretoryductal NOS and variants: generalchoriocarcinomatousmelanoticmixedosteoclastic giant cellspleomorphic //;  glycogen richinflammatoryintracystic papillaryintralymphaticlipid richlobular carcinoma and variants: classicalveolarbasal-likehistiocytoidpleomorphicsignet-ringsolidtrabecular //;  luminallymphoepithelioma-likemedullarymetaplastic carcinoma and subtypes: generalfibromatosis-likematrix producingspindle cell //;  metastases to breastmicropapillarymixed ductal and lobularmucin-producingmucinousmucinous cystadenocarcinomamucoepidermoidmyoepithelialneuroendocrine carcinoma and variants: generalsolidlarge cell //;  oncocyticpapillary sebaceoussecretorysignet ringsmall cellsquamous cellsquamous cell-acantholytictall-cell liketubulartubulolobular

 

Sarcoma: general,  angiosarcoma,  leiomyosarcoma,  liposarcomalow grade myofibroblastic sarcomaMFHMPNSTosteosarcoma,  rhabdomyosarcoma,  sarcoma NOS,  stromal sarcoma

 

Other malignancies: lymphoma,  myeloid sarcoma,  plasmacytoma,  Rosai-Dorfman

 

Childhood tumors: general,  juvenile fibroadenoma,  juvenile papillomatosis,  carcinoma

 

Male tumors: general,  gynecomastia,  myofibroblastoma,  papilloma,  carcinoma,  metastases

 

Miscellaneous: treatment effect - chemotherapy,  cryoprobe,  hormone therapy,  radiation therapy //;  frozen sectionsgrossingfeatures to reportstaging

 

Go to Breast-nonmalignant chapter

 

Primary references

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AJCC Cancer Staging Manual (6th Ed)

American Journal of Clinical Pathology

American Journal of Surgical Pathology

Archives of Pathology and Laboratory Medicine

Biomed Central

BMC Clinical Pathology

Cytojournal

Human Pathology

Modern Pathology

Rosen: Tumors of the Mammary Gland (AFIP Fascicle, 3rd series, volume 7); 1994

Rosai, J:  Ackerman’s Surgical Pathology (9th Ed), Mosby, 2004

Sternberg, S: Diagnostic Surgical Pathology (4th Ed); Lippincott Williams & Wilkins, 2004

Tavassoli: Tumours of the Breast and Female Genital Organs (WHO, 2003)

Websites (images): Digital Atlas of Breast Pathology, Geneva Foundation for Medical Education and Research, Johns Hopkins Breast Center, National Institutes of Health, Online Management of Breast Diseases, PathConsult, PathoPic

Virtual slides - USCAP, vSlides

Journal search terms: each disease entity listed

 

Please refer to these primary references for more detailed discussions and photographs

 

End of Breast-malignant, males, children chapter

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Go to Breast-nonmalignant chapter