Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Breast malignant, males, children


Reviewers: Dina Kandil, M.D., Monika Roychowdhury, M.D., Daniel Visscher, M.D. (see Reviewers page)
Revised: 7 February 2012, last major update February 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

Table of contents


Primary references

In situ carcinoma: DCIS - generalapocrinebasal-likeclingingcomedocribriformcystic hypersecretorymicropapillarymucinousneuroendocrinepapillarysignet ring cellsolidsolid papillaryspindle cellsquamous cell / Bowen’s disease
LCIS - classicpleomorphic
other - ductal intraepithelial neoplasia (DIN)mammary intraepithelial neoplasiaPaget’s disease


Breast cancer: generalaxillary nodesEGFR,  HER2histologic gradinghormone receptorsmicroinvasivepregnancyrisk factorssentinel nodesspread/metastasessuspiciousWHO classification
prognostic factors: generalangiolymphatic invasionfibrotic focusmultigene products


Carcinoma subtypes: generalacinic celladenoid cysticadenosquamousapocrinebasal cell-nipplebasal-likeBRCA1BRCA2central acellularcribriformcystic hypersecretory
ductal NOS and variants: generalchoriocarcinomatousmelanoticmixedosteoclastic giant cellspleomorphic
glycogen richinflammatoryintracystic papillaryintralymphaticlipid rich
lobular carcinoma and variants: classicalveolarbasal-likehistiocytoidpleomorphicsignet-ringsolidtrabecular
luminallymphoepithelioma-likemedullary
metaplastic carcinoma and subtypes: generalfibromatosis-likematrix producingspindle cell
metastases to breastmicropapillarymixed ductal and lobularmucin-producingmucinousmucinous cystadenocarcinomamucoepidermoidmyoepithelial
neuroendocrine carcinoma and variants: generalsolidlarge cell
oncocyticpapillarysebaceoussecretorysignet ringsmall cellsquamous cellsquamous cell-acantholytictall-cell liketubulartubulolobular


Sarcoma: general,  angiosarcoma,  leiomyosarcoma,  liposarcomalow grade myofibroblastic sarcomaMFHMPNSTosteosarcoma,  rhabdomyosarcoma,  sarcoma NOS,  stromal sarcoma

Other malignancies: lymphoma,  myeloid sarcoma,  plasmacytoma,  Rosai-Dorfman

Childhood tumors: general,  juvenile fibroadenoma,  juvenile papillomatosis,  carcinoma

Male tumors: general,  gynecomastia,  myofibroblastoma,  papilloma,  carcinoma,  metastases

Miscellaneous: treatment effect - chemotherapy,  cryoprobe,  hormone therapy,  radiation therapy
frozen sectionsgrossingfeatures to reportstaging


Go to Breast-nonmalignant chapter

Primary references

top

AJCC Cancer Staging Manual (7th ed)
American Journal of Clinical Pathology
American Journal of Surgical Pathology
Archives of Pathology and Laboratory Medicine
Human Pathology
Modern Pathology
Rosen: Tumors of the Mammary Gland (AFIP Fascicle, 3rd series, volume 7); 1994
Tavassoli: Tumours of the Breast and Female Genital Organs (WHO, 2003)
Virtual slides: USCAPvSlides
Websites: Digital Atlas of Breast PathologyNational Institutes of HealthOnline Management of Breast DiseasesPathoPicWebpathology.com

Please refer to these primary references for more detailed discussions and photographs

End of Breast-malignant, males, children chapter