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Cervix-Cytology
Reviewers: Farnaz Hasteh, M.D., UCSD Medical Center; Varsha Manucha, M.D., Temple University; Nat Pernick, M.D., PathologyOutlines.com, Inc.; Marilin Rosa, M.D., University of Florida and Xinmin Zhang, M.D., Temple University
Revised: 24 September 2012, last major update June 2011
Copyright: (c) 2006-2012, PathologyOutlines.com, Inc.
Table of contents - Cervix-cytology
Primary references, general, Pap, liquid based, Diff-Quik, Bethesda system
Normal / benign / non-neoplastic:
benign features-general, adenomyoma, adenosis, air drying artifact, Arias-Stella reaction, atrophy, atypical polypoid adenomyoma, Barr body, blue blobs, cilia, cornflakes, decidual reaction, degeneration, endocervical cells, endocervical polyp, endometrial cells, endometrial polyp, endometriosis, endosalpingiosis / tubal metaplasia, eosinophils, exodus, florid ectopy, histiocytes, hyperkeratosis, insect parts, intermediate squamous cells, leiomyoma, lobular endocervical hyperplasia, lower uterine segment endometrium, lymphocytes, male cells, maturation index, mesonephric hyperplasia, mesonephric remnants, microglandular hyperplasia, navicular cells, neutrophils, parabasal cells, parakeratosis, PM cells, post-hysterectomy, psammoma bodies, repair, small blue cells, squamous cells, squamous metaplasia, squamous papilloma, syncytium, transitional metaplasia, tumor diathesis, unsatisfactory specimen
Inflammation/parasites:
actinomycosis,
bacterial vaginosis,
Candida,
chlamydia,
chronic cervicitis,
CMV,
Enterobius,
granuloma inguinale,
granulomas,
herpes/HSV,
Lactobacillus,
Leptothrix,
Schistosomiasis,
syphilis,
Trichomonas,
tuberculosis,
Wucheria
Atypia / Premalignant / preinvasive lesions:
adenocarcinoma in situ (AIS), atypical glandular cells (AGC), atypical repair, atypical reserve cell hyperplasia, atypical squamous cells (ASC), chemotherapy effect, condyloma, HPV, HSIL/CIN II, HSIL/CINIII, LSIL/CIN I, Paget's disease, radiation atypia, SIL-general
Carcinoma:
adenocarcinoma, adenocarcinoma-microinvasive, adenoid basal, adenoid cystic, adenosquamous, clear cell, endometrial, glassy cell, lymphoepithelioma-like, metastases to cervix, minimal deviation adenocarcinoma, serous papillary adenocarcinoma, signet ring cell, small cell, squamous cell carcinoma, squamous cell-microinvasive, urothelial, verrucous, villoglandular papillary adenocarcinoma, warty
Sarcoma / lymphoma / other:
sarcoma-general, granulocytic sarcoma, leiomyosarcoma, lymphoma, malignant mixed mullerian tumor (MMMT), melanoma, plasmacytoma, rhabdomyosarcoma, stromal sarcoma
Alphabetical table of contents
A-E: actinomycosis, adenocarcinoma, adenocarcinoma in situ (AIS), adenocarcinoma-microinvasive, adenoid basal, adenoid cystic, adenomyoma, adenosis, adenosquamous, air drying artifact, Arias-Stella reaction, atrophy, atypical glandular cells (AGC), atypical polypoid adenomyoma, atypical repair, atypical reserve cell hyperplasia, atypical squamous cells (ASC), bacterial vaginosis, Barr body, benign features-general, Bethesda system, blue blobs, Candida, chemotherapy effect, chlamydia, chronic cervicitis, cilia, clear cell, CMV, condyloma, cornflakes, decidual reaction, degeneration, Diff-Quik, endocervical cells, endocervical polyp, endometrial adenocarcinoma, endometrial cells, endometrial polyp, endometriosis, endosalpingiosis / tubal metaplasia, Enterobius, eosinophils, exodus
F-N: florid ectopy, general, glassy cell carcinoma, granulocytic sarcoma, granuloma inguinale, granulomas, herpes/HSV, histiocytes, HPV, HSIL/CIN II, HSIL/CINIII, hyperkeratosis, insect parts, intermediate squamous cells, Lactobacillus, leiomyoma, leiomyosarcoma, Leptothrix, liquid based, lobular endocervical hyperplasia, lower uterine segment endometrium, LSIL/CIN I, lymphocytes, lymphoepithelioma-like carcinoma, lymphoma, male cells, malignant mixed mullerian tumor (MMMT), maturation index, melanoma, mesonephric hyperplasia, mesonephric remnants, metastases to cervix, microglandular hyperplasia, minimal deviation adenocarcinoma, navicular cells, neutrophils
O-Z: Paget's disease, Pap, parabasal cells, parakeratosis, plasmacytoma, PM cells, post-hysterectomy, psammoma bodies, radiation atypia, repair, rhabdomyosarcoma, sarcoma-general, Schistosomiasis, serous papillary adenocarcinoma, signet ring cell carcinoma, SIL-general, small blue cells, small cell carcinoma, squamous cell carcinoma, squamous cell carcinoma-microinvasive, squamous cells, squamous metaplasia, squamous papilloma, stromal sarcoma, syncytium, syphilis, transitional metaplasia, Trichomonas, tuberculosis, tumor diathesis, unsatisfactory specimen, urothelial carcinoma, verrucous carcinoma, villoglandular papillary adenocarcinoma, warty carcinoma, Wucheria
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Primary references
American Journal of Clinical Pathology
American Journal of Surgical Pathology
Archives of Pathology and
Laboratory Medicine
Human Pathology
Modern Pathology
DeMay: The Pap Test: Exfoliative Gynecologic Cytology (1st Ed); ASCP, 2005
Solomon:
The Bethesda System for Reporting Cervical Cytology (2nd Ed); Springer, 2005
Websites: Cytopathology of the Uterine Cervix-Digital Atlas, American
Society of Cytopathology-National Cancer Institute Atlas, Johns Hopkins Cytopathology Tutorial
Please refer to these primary references for additional discussion and images