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Colon tumor


Reviewers: Jela Bandovic, M.D., Shilpa Jain, M.D., Charanjeet Singh, M.D. (see Reviewers page)
Revised: 25 May 2012, last major update May 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

Primary references

Molecular pathways: generalchromosomal pathwayCpG islandmicrosatellite instabilityMUTYH pathway

Polyps: generalbiopsiesaberrant crypt fociadenomacarcinoma arising in adenomaadenoma-carcinoma sequenceatheroembolicap polyposisdisplaced glandsdiverticularfibroblasticflat adenomahyperplasticinflammatoryinflammatory fibroidinflammatory myoglandularjuvenilelymphoidPeutz-Jegherpost-surgicalserratedtransitionaltubular adenomatubulovillous adenomavillous adenoma

Familial polyposis syndromes: APC geneCowden’sCronkhite-Canadafamilial adenomatous polyposis-classicattenuatedGardner’shereditary mixed polyposishyperplastic polyposisjuvenile polyposisLynchMuir-TorreMUTYH associatedPeutz-JegherTurcot’s

Carcinoma: generalWHO classificationpost-treatment changesintramucosaladenocarcinomaadenosquamouscarcinosarcomaclear cellglassy cellhepatoidlymphoepithelioma-likemedullarymetastases to colonmucinousneuroendocrinepapillarysignet ringsmall cellsmall early flatsquamous cellvillous

Carcinoid tumors: rectumnot rectum

Lymphoma and hematopoietic lesions: generalBurkittfollicularHHV8HodgkinMALTmantle cellmast cell sarcomaT cell

Mesenchymal tumors: generalangiomyolipomaangiosarcomaendometrial stromal sarcomafibromatosisganglioneuromatosisGANTGISThemangiomahistiocytic sarcomaidiopathic retractile mesenteritisidiopathic retroperitoneal fibrosisinflammatory myofibroblastic tumorKaposi’s sarcomaleiomyomaleiomyomatosisleiomyomatosis-like lymphangioleiomyomatosisleiomyosarcomalipomalipomatosisliposarcomaMullerian adenosarcomaperineuriomaperivascular epithelioid cell tumorpyogenic granulomareactive nodular fibrous pseudotumorschwannomasolitary fibrous tumor

Other tumors: Langerhans cell histiocytosisRosai-Dorfman diseaseteratoma

Other: grossingstagingstaging-neuroendocrinefeatures to report

Index (table of contents in alphabetical order)

A-E: aberrant crypt foci, adenocarcinoma, adenomaadenoma-carcinoma sequenceadenosquamous carcinomaangiomyolipomaangiosarcomaAPC geneatheroembolibiopsiesBurkitt lymphomacap polyposiscarcinoid-not rectumcarcinoid-rectumcarcinoma-generalcarcinoma arising in adenomacarcinosarcomachromosomal pathway, clear cell carcinoma, Cowden’s polyposis syndromeCpG island pathway, Cronkhite-Canada syndromedisplaced glands in polypdiverticular polypendometrial stromal sarcoma

F-N: familial adenomatous polyposis-classicFAP attenuated polyposis syndromefeatures to report, fibroblastic polypfibromatosisflat adenomafollicular lymphomaganglioneuromatosisGANTGardner’s syndromeGISTglassy cell carcinomagrossinghemangiomahepatoid carcinomahereditary mixed polyposis syndromeHHV8 lymphomahistiocytic sarcomaHodgkin lymphomahyperplastic polyphyperplastic polyposis syndrome, idiopathic retractile mesenteritisidiopathic retroperitoneal fibrosisinflammatory fibroid polypinflammatory myofibroblastic tumorinflammatory myoglandular polypinflammatory polyp, intramucosal carcinomajuvenile polypjuvenile polyposis syndrome, Kaposi’s sarcomaLangerhans cell histiocytosisleiomyomaleiomyomatosisleiomyomatosis-like lymphangioleiomyomatosisleiomyosarcomalipomalipomatosisliposarcomalymphoepithelioma-like carcinomalymphoid polyplymphoma-generalLynch syndromeMALT lymphomamantle cell lymphomamast cell sarcomamedullary carcinomamesenchymal tumors-generalmetastases to colonmicrosatellite instability pathwaymolecular pathways-generalmucinous carcinomaMuir-Torre syndromeMullerian adenosarcomaMUTYH associated polyposisMUTYH pathwayneuroendocrine carcinoma

O-Z: papillary carcinomaperineuriomaperivascular epithelioid cell tumorPeutz-Jegher polyp, Peutz-Jegher syndrome, polyps-generalpost-surgical polyppost-treatment changes (carcinoma)pyogenic granulomaRosai-Dorfman diseasereactive nodular fibrous pseudotumorschwannomaserrated polypsignet ring carcinomasmall cell carcinomasmall early flat carcinomasolitary fibrous tumorsquamous cell carcinomastagingstaging-neuroendocrineT cell lymphomateratomatransitional polyptubular adenomatubulovillous adenomaTurcot’s syndromevillous adenomavillous carcinomaWHO classification of colon carcinoma


Go to Colon-nontumor chapter

Primary references

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AJCC Cancer Staging Manual (7th ed)
American Journal of Surgical Pathology
Archives of Pathology and Laboratory Medicine
Human Pathology
Modern Pathology
Websites with images: PathoPic

Please refer to these primary references for more detailed discussions and photographs

End of Colon-tumor chapter