Updates of the WHO Classification of Brain and Pituitary Tumors
For the first time, the 2016 WHO classification of central nervous system (CNS) tumors uses molecular parameters in addition to histology to define many tumor entities, thus formulating a concept for how CNS tumor diagnoses should be structured in the molecular era. These new updates will facilitate clinical, experimental and epidemiological studies that will lead to improvements in the lives of patients with brain tumors. General pathologists, in particular, must become familiar with changes in diagnostic criteria and utilize them in their practice improvement strategies. The WHO classification of pituitary adenomas was revised in 2017 and includes (1) a recommendation for the assessment of pituitary transcription factors with focus on adenohypophysial-cell lineage and (2) replacement of “atypical adenoma” with “high risk adenoma” based on tumor proliferation markers and other clinical parameters (such as invasion) to predict aggressiveness. This course will illustrate and reinforce these important updates.
Course Location: Palm Springs, CA
Course Director: Arie Perry, M.D.