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October 2012: Laboratories

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Laboratories: Cornerstone of Pathology Practice
Jaleh Mansouri, M.D.


Pathology laboratories provide the basic platform for the delivery of pathology services in both anatomic and clinical pathology. Most laboratories operate either within a hospital or in a private community setting. Reference and research laboratories are especially suited for conducting complex or esoteric tests that require specialized instrumentation (e.g. flow cytometry) and/or expertise in a subspecialty field (e.g. molecular genetics, hematopathology).

Reference laboratories (e.g. ARUP, Mayo Medical Laboratories, Quest Diagnostics, etc.) play a significant role in the delivery of pathology services as the number and complexity of available tests continue to increase. Current economic forces within the health care industry have prompted referring laboratories to carefully analyze test volume, third-party reimbursement, and reference laboratory utilization reports in order to make cost-effective decisions regarding send-out versus in-house testing. Potential concerns of send-out testing for referring laboratories include turn-around times, remote access to laboratory results, and accuracy and standardization of CPT (current procedural terminology) coding. One potential barrier that reference laboratories may face is restricted access to patient clinical histories either due to HIPAA (Health Insurance Portability and Accountability Act) regulations and/or lack of interface capabilities with the referring institution. These issues underline the importance of direct communication among the reference laboratory, referring laboratory, and clinicians in optimizing patient health care.

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ARUP Laboratories: Founded in 1984, ARUP Laboratories is a leading national reference laboratory and a nonprofit enterprise of the University of Utah and its Department of Pathology. ARUP offers more than 3,000 tests and test combinations, ranging from routine screening tests to esoteric molecular and genetic assays. ARUP serves clients across the United States, including many of the nation's top university teaching hospitals, as well as multihospital groups, major commercial laboratories, and major clinics. In addition, ARUP is a worldwide leader in innovative laboratory research and development, led by the efforts of the ARUP Institute for Clinical and Experimental Pathology®. For more information, click here.

bioTheranostics discovers and develops innovative diagnostic technologies for oncology, designed to improve patient care from the time of diagnosis through selection of appropriate treatment. The company's initial diagnostic test offerings are: (1) CancerTYPE ID®, which improves cancer classification, especially in patients with metastatic cancer and an unknown primary. It is based on a 92-gene qRT-PCR panel and capable of identifying up to 39 tumor types with 86% accuracy. (2) THEROS Breast Cancer Index® - This provides a more complete picture of recurrence risk and therapeutic options for patients by combining the results of the THEROS H/I and THEROS MGI tests, to better stratify ER-positive, node-negative breast cancer patients. bioTheranostics is also working on prostate cancer prognosis and drug-response profiling. Email Brittany.Rothnem@biotheranostics.com or call 858 587 5883 for more information.

Cleveland Clinic Laboratories offers online Immunohistochemical (IHC) stained eSlides to optimize clinical workflow. Rapid access to case, specimen and slide information is conveniently at your fingertips through a secure internet site accessible anytime, anywhere. Cleveland Clinic Laboratories has been providing the highest quality laboratory testing services for more than 25 years. We are a full-service, national reference lab dedicated to providing world class care. We recently debuted our new, state-of-the-art laboratory building, featuring sustainable practices, cutting-edge technology and designs created with input from employees. Physicians and health care facilities across the country rely on the specialists at Cleveland Clinic Laboratories to provide the expert diagnosis, second opinions and subspecialty consultation that are the basis for effective patient care. TRUST in us for everything you need in a reference lab. For more information on our reference lab and eIHC services, visit clevelandcliniclabs.com/eIHC.

ProPath® is one of the largest physician-owned anatomic pathology group practices serving clinicians nationwide. We have been providing reliable and convenient pathology services since 1966, and remain devoted to comprehensive, quality diagnostic testing for unsurpassed patient care. Our practice and internationally-recognized immunohistochemistry laboratory have one of the most competitive turnaround times for routine specimens. Our team of nearly 40 board certified pathologists offer subspecialty training and expertise in Dermatopathology, Gastrointestinal Pathology, Hematopathology, Cytopathology, Breast Pathology, Urologic Pathology, Podiatric Pathology, Surgical Pathology, Renal Pathology, Molecular Diagnostics and Immunohistochemistry. Visit www.propath.com to find out more about ProPath.

Past / future feature pages:

June 2012: Diagnostic testing / reagents
July 2012: Imaging / digital / photography
August 2012: Books & Journals
September 2012: Antibodies

November 2012: Consumable Lab Products / Clinical Lab Analyzers
December 2012: Grossing workstations / lab furniture
January 2013: Billing / consulting / management
February 2013: Microscopes / slide imaging
March 2013: Tissue processors / other histology
April 2013: Laboratory Accreditation / Education / CME
May 2013: Computer software and systems
June 2013: Diagnostic testing / reagents
July 2013: Imaging / digital / photography
August 2013: Books & Journals
September 2013: Antibodies
October 2013: Laboratories

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