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February 2013:
Microscopes / Microscopy Products


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Microscopes and Slide Imaging: Exploring a Microcosm
Jaleh Mansouri, M.D.


The compound light microscope has served as the pathologist's primary tool of his trade since pathology was first recognized as an independent medical specialty in the early 20th century. Throughout the years, technological advances in different scientific fields have contributed to the development of novel microscopic techniques such as fluoroscopic and electron microscopy. The rise of information technology has further transformed the field of microscopy and pathology in dramatic ways. While most surgical pathologic diagnoses today are still rendered by looking into the microscope, the digital era may soon replace the objective with a computer screen as digital systems continue to be incorporated in pathology laboratories and departments across the country.

Whole slide imaging is a relatively new modality that encompasses the concept of virtual microscopy. In this technique, whole glass slides are scanned with a slide scanner, and the captured visual data is then transmitted to a computer. Digital systems designed for pathology laboratories may employ lossy compression to facilitate transmission, a type of compression technique whereby transmitted data is fully reconstructed without loss or compromise of information. While whole slide imaging systems are being used in education, research, and telepathology, the future role this modality will play in diagnostic pathology remains unclear as FDA (Food and Drug Administration) regulators continue to evaluate these medical devices.


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Celestron: Since manufacturing its first telescope in 1960, Celestron has grown to become one of the world's leading telescope makers and enjoys brand-name recognition among serious amateur astronomers for superior optics, outstanding design, and innovative technology. In keeping with this reputation, Celestron microscopes combine the highest quality precision optics with mechanical designs that are state-of-the-art. Celestron professional microscopes are designed for microbiology, pathology, entomology, dermatology, dental usage, veterinary use, and everyday analysis of specimens through advanced research. All Celestron microscopes use high quality glass optics and the bodies are made of metal. Please visit www.celestron.com.

Leica Microsystems is a leading global developer and manufacturer of a broad range of innovative, high-tech, precision optical systems for the imaging, measurement, and analysis of microstructures. Leica Microsystems is one of the market leaders in each of its four divisions: Life Science, Industry, Biosystems, and Surgical. Business areas include Microscopy and Imaging Systems, Specimen Preparation, Medical Equipment, and Antibodies and Reagents. The company offers instruments and system solutions for the entire histopathology process including the NovocastraTM range of antibodies and reagents, consumable products, and clinical microscopes. The company is represented in over 100 countries with 9 manufacturing facilities in 7 countries, sales and service organizations in 20 countries and an international network of dealers.

Optronics provides Microcast® HD real-time High Definition Co-Observation, which replaces multi-head microscopes. The Optronics Microcast HD offers full 1080p HD digital co-observation from a microscope with 2MP progressive scan digital images at 60 FPS. The camera system uses 3CCD medical grade RGB imaging technology for precise real-time color reproduction of microscope images without interpolation. The camera's ultra high speed automatic camera shutter instantaneously compensates for higher magnification objectives and decreases in illumination. Optional full 1080p HD image capture of HD microscope images without a computer is available for reports and publications. Microcast HD eliminates the need for a multi-head microscope. For more information, please visit http://www.optronics.com.

Past / future feature pages:

January 2013: Billing / consulting / management
February 2013: Microscopes / Microscopy Products

March 2013: Tissue processors / other histology
April 2013: Laboratory Accreditation / Education / CME
May 2013: Computer software and systems
June 2013: Diagnostic testing / reagents
July 2013: Imaging / digital / photography
August 2013: Books & Journals
September 2013: Antibodies
October 2013: Laboratories
November 2013: Consumable Lab Products / Clinical Lab Analyzers
December 2013: Grossing Equipment / Workstations
January 2014: Billing / consulting / management
February 2014: Microscopes / Microscopy Products

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