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Leukemia - Acute
Reviewers: Daniela Mihova, M.D.; Syed Zaidi, M.D. (see Reviewers page)
Revised: 27 March 2013, last major update September 2012
Copyright: (c) 2001-2013, PathologyOutlines.com, Inc.
Table of contents
Primary references acute leukemia-general AML general AML classification transient abnormal myelopoiesis
Recurrent genetic abnormalities: AML with t(6;9) AML with t(8;21) AML with 11q23 abnormalities AML with inv(16) or t(16;16) AML with Down syndrome AML with FLT3 mutations AML with myelodysplastic related changes AML therapy related APL microgranular variant APL with t(15;17) APL with t(V;17) APL therapy related
AML not otherwise categorized: minimally differentiated (M0) without maturation (M1) with maturation (M2) M3 myelomonocytic monoblastic and monocytic erythroid megakaryoblastic CD13/CD33 negative basophilic myeloid sarcoma acute panmyelosis with myelofibrosis with Philadelphia chromosome with pseudo Chediak-Higashi anomaly hypocellular
ALL: general WHO classification with eosinophilia
PreB ALL: general t(9;22) t(v;11q23) t(1;19) t(5;14) t(12;21) hyperdiploidy hypodiploidy mature B ALL/Burkitt
Other ALL: T ALL ambiguous lineage mixed phenotype
SuperPage: entire chapter
Index (table of contents in alphabetical order)
Miscellaneous: acute leukemia-general acute panmyelosis with myelofibrosis transient abnormal myelopoiesis
ALL: ambiguous lineage general mixed phenotype WHO classification with eosinophilia T-ALL
B-ALL: general mature/Burkitt with hyperdiploidy with hypodiploidy with t(1;19) with t(5;14) with t(9;22) with t(12;21) with t(v;11q23)
AML: basophilic CD13/CD33 negative classification erythroid general hypocellular M3 megakaryoblastic minimally differentiated (M0) monoblastic and monocytic myeloid sarcoma myelomonocytic therapy related with 11q23 abnormalities with Down syndrome with FLT3 mutations with inv(16) or t(16;16) with maturation (M2) with myelodysplastic related changes with Philadelphia chromosome with pseudo Chediak-Higashi anomaly with t(6;9) with t(8;21) without maturation (M1)
APL: microgranular variant therapy related with t(15;17) with t(V;17)
Primary references
top
Brunning: Tumors of the Bone Marrow (AFIP Atlas of Tumor Pathology, Series 3, Vol 9, 1994)
End of Leukemia-acute chapter