Pathology Outlines - Leukemia

Leukemia - Acute

Authors: Daniela Mihova, M.D.; Syed Zaidi, M.D. (see Authors page)

Revised: 17 August 2016, (c) 2001-2016, PathologyOutlines.com, Inc.

HemePath related: Jobs, Fellowships, Conferences, Cases, CME

Related chapters: Bone marrow, Chronic myeloid, Hematology, Lymph nodes, Lymphoma, Spleen

Table of contents

Primary references acute leukemia-general AML general AML classification transient abnormal myelopoiesis

Recurrent genetic abnormalities: AML with t(6;9) AML with t(8;21) AML with 11q23 abnormalities AML with inv(16) or t(16;16) AML with Down syndrome AML with FLT3 mutations AML with myelodysplastic related changes AML therapy related APL microgranular variant APL with t(15;17) APL with t(V;17) APL therapy related

AML not otherwise categorized: minimally differentiated (M0) without maturation (M1) with maturation (M2) M3 myelomonocytic monoblastic and monocytic erythroid megakaryoblastic CD13/CD33 negative basophilic myeloid sarcoma acute panmyelosis with myelofibrosis with Philadelphia chromosome with pseudo Chediak-Higashi anomaly hypocellular

ALL: general WHO classification with eosinophilia

PreB ALL: general t(9;22) t(v;11q23) t(1;19) t(5;14) t(12;21) hyperdiploidy hypodiploidy mature B ALL/Burkitt

Other ALL: T ALL ambiguous lineage mixed phenotype

SuperPage: entire chapter

Primary references
top

Brunning: Tumors of the Bone Marrow (AFIP Atlas of Tumor Pathology, Series 3, Vol 9, 1994)