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Table of contents

Primary referencesnormal anatomynormal histologyembryologynormal physiologypatterns of hepatic injurybiopsydiagnostic patterns

Developmental anomalies/cysts: accessory lobeAlagille’s syndromeBloom syndromeByler’s diseaseCaroli’s diseasecholedochal cystcongenital hepatic fibrosisDown’s syndromeextrahepatic biliary atresiaforegut cystintrahepatic biliary atresiamultiple hilar cystspolycystic liver diseasesolitary cystvon Meyenburg complex

Metabolic diseases: generalalpha-1-antitrypsin deficiencycystic fibrosiserythropoietic protoporphyriafamilial apolipoprotein A-I amyloidosisgalactosemiaGaucherglycogen storage diseaseGM2 gangliosidosisheme oxygenase-1 deficiencyhemochromatosishereditary fructose intolerancehereditary hepatic coproporphyriahereditary tyrosinemiamucopolysaccharidosisNiemann-Pickporphyria cutanea tardaprimary hyperoxaluriaWilson’s diseaseWolman diseaseZellweger syndrome

General concepts: ascitescirrhosiscirrhosis-features to reportdifferential diagnosis of fibrosisfulminant hepatitis / massive hepatic necrosishepatic failure

Hepatitis (acute and chronic): generalacute hepatitis-generalprolonged resolving acute hepatitischronic hepatitis-generalchronic hepatitis-grading and staging

Hepatitis (non-infectious): alcoholicautoimmunedrug/toxin-inducedgranulomatousneonatalnonalcoholic steatohepatitistotal parenteral nutrition related

Infectious (non-viral) disorders: AspergillusbacterialBlastomycosisCandidaClonorchis sinensisCoccidiodomycosisCoxiellaCryptococcusdengue feverEchinococcal cystEchovirusEntamoeba histolyticaFasciola hepaticagranulomatousHistoplasmamalakoplakiamicrosporidiaMucorMycobacteriaOrientia tsutsugamushiPenicilliumpyogenic abscessReye’s syndromeSalmonellaSchistosomiasisvisceral larva migransvisceral leishmaniasis

Viral hepatitis: generalacute viral hepatitischronic viral hepatitisadenovirusCMVEBVhepatitis Ahepatitis Bhepatitis CDelta agenthepatitis Ehepatitis GherpesHHV6HIV

Biliary tract disease: cholestasisacute large duct obstructionascending cholangitisautoimmune cholangitischolangitis lentachronic large duct obstructionhyperalimentationoriental cholangiohepatitisprimary biliary cirrhosisprimary sclerosing cholangitissecondary biliary cirrhosis

Jaundice: physiologyunconjugated hyperbilirubinemiaconjugated hyperbilirubinemia

Vascular disorders: generalarterial disordersBudd-Chiarihepatoportal sclerosishemorrhagic hereditary telangiectasiapeliosis hepatisportal hypertensionportal vein obstructionveno-occlusive disease

Systemic diseases/conditions: amyloidosiscongestive heart failureCrohn’s diseasediabetes mellitushemolytic anemiamyeloproliferative disorderspregnancyrheumatoid arthritissarcoidosissickle cell diseaseulcerative colitis

Transplantation: liver transplant-generaladult to adult liver donor transplantationhyperacute graft rejectionacute graft rejectionchronic graft rejectionpost-bone marrow transplantacute graft versus host diseasechronic GVHDposttransplant lymphoproliferative disorderpseudopeliotic steatosis


Index (table of contents in alphabetical order)

A-E: accessory lobeacute graft rejectionacute graft versus host diseaseacute hepatitis-generalacute large duct obstructionacute viral hepatitisadenovirusadult to adult liver donor transplantationAlagille’s syndromealcoholic hepatitisalpha-1-antitrypsin deficiencyamyloidosisarterial disordersascending cholangitisascitesAspergillusautoimmune cholangitisautoimmune hepatitisbacterial infectionBlastomycosisBloom syndromeBudd-ChiariByler’s diseaseCandidaCaroli’s diseasecholangitis lentacholedochal cystcholestasischronic graft rejectionchronic GVHDchronic hepatitis-generalchronic hepatitis-grading and stagingchronic large duct obstructionchronic viral hepatitiscirrhosiscirrhosis-features to reportClonorchis sinensisCMVCoccidiodomycosiscongenital hepatic fibrosiscongestive heart failureconjugated hyperbilirubinemiaCoxiellaCrohn’s diseaseCryptococcuscystic fibrosisDelta agentdengue feverdiabetes mellitusdiagnostic patternsdifferential diagnosis of fibrosisDown’s syndromedrug/toxin-induced hepatitisEBVEchinococcal cystEchovirusembryologyEntamoeba histolyticaerythropoietic protoporphyriaextrahepatic biliary atresia

F-N: familial apolipoprotein A-I amyloidosisFasciola hepaticaforegut cystfulminant hepatitis / massive hepatic necrosisgalactosemiaGaucherglycogen storage diseaseGM2 gangliosidosisgranulomatous hepatitisgranulomatous infectionheme oxygenase-1 deficiencyhemochromatosishemolytic anemiahemorrhagic hereditary telangiectasiahepatic failurehepatitis Ahepatitis Bhepatitis Chepatitis Ehepatitis Ghepatitis-generalhepatoportal sclerosishereditary fructose intolerancehereditary hepatic coproporphyriahereditary tyrosinemiaherpesHHV6HistoplasmaHIVhyperacute graft rejectionhyperalimentationintrahepatic biliary atresiajaundice-physiologyliver biopsyliver transplant-generalmalakoplakiametabolic diseases-generalmicrosporidiamucopolysaccharidosisMucormultiple hilar cystsMycobacteriamyeloproliferative disordersneonatal hepatitisNiemann-Picknonalcoholic steatohepatitisnormal anatomynormal histologynormal physiology

O-Z: oriental cholangiohepatitisOrientia tsutsugamushipatterns of hepatic injurypeliosis hepatisPenicilliumpolycystic liver diseaseporphyria cutanea tardaportal hypertensionportal vein obstructionpost-bone marrow transplantposttransplant lymphoproliferative disorderpregnancyprimary biliary cirrhosisprimary hyperoxaluriaPrimary referencesprimary sclerosing cholangitisprolonged resolving acute hepatitispseudopeliotic steatosispyogenic abscessReye’s syndromerheumatoid arthritisSalmonellasarcoidosisSchistosomiasissecondary biliary cirrhosissickle cell diseasesolitary cysttotal parenteral nutrition related hepatitisulcerative colitisunconjugated hyperbilirubinemiavascular disease-generalveno-occlusive diseaseviral hepatitis-generalvisceral larva migransvisceral leishmaniasisvon Meyenburg complexWilson’s diseaseWolman diseaseZellweger syndrome

Go to Liver and intrahepatic bile ducts - tumor chapter


Primary references
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AJCC Cancer Staging Manual (7th Ed)
Websites: Loyola University


Recent Liver pathology books

Burt: 2011

Chan: 2013

Ferrell: 2011

Iacobuzio-Donahue: 2011

Kaplowitz: 2013

Lamps: 2011

Mullen: 2012

Riddell: 2014

Russo: 2014

Saxena: 2011

Suriawinata: 2011

Wee: 2014

Yantiss: 2011


Click here for other Liver pathology books


End of Liver and intrahepatic bile ducts - Non tumor chapter



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