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This page contains announcements of new pathology products and services from advertisers. Most announcements are posted for 90 days and then removed. For more information, please contact us at PathOutSales@gmail.com or at 248/646-0325.

28 January 2012: Mopec announces its Post Mortuary Knife, a new product for the New Year. Excellent for autopsy and gross dissection, it is 8.75" long (222.25 mm), with an extra sharp cutting edge, an ergonomical handle grip and a protective sheath. Its 3.5" (88.9 mm) carbon steel blade has a specially ground edge, and is mounted in a blue poly handle, ergonomically designed for easy gripping in wet situations. The easy to remove blade sheath protects the user both before and after use.

The price is only $9.25 each ($8.50 for 6-11, $8.00 for 12 or more), with same day shipping. Product number is AJ129.

For more information, please visit us at http://www.mopec.com.

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10 January 2012: Modern Pathology, the official journal of the United States and Canadian Academy of Pathology (USCAP), announces the following free articles in its January 2012 issue:

Histopathology of 2009 H1N1

CXCR4 in thyroid carcinomas

Postradiation angiosarcoma

Modern Pathology's main focus is original papers reporting innovative clinical and translational research in the pathology of human disease. Access to all content is FREE 12 months post-publication. Visit the journal website at http://www.modernpathology.org.

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10 January 2012: Laboratory Investigation, the official journal of the United States and Canadian Academy of Pathology, presents the following free articles in its January 2012 issue:

Squamous epithelium barrier function

Fascin expression in hepatic stellate cells

Epidermal regulation of dermal angiogenesis

Laboratory Investigation is an international journal owned by The United States and Canadian Academy of Pathology and edited by a board appointed by the Council of the Academy. Laboratory Investigation offers prompt publication of high-quality original research in all biomedical disciplines relating to the understanding of human disease and the application of new methods to the diagnosis of disease. Visit us online at http://www.laboratoryinvestigation.org.

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6 January 2012: Epitomics is pleased to showcase c-Myc and HER2 / ErbB2, two high quality rabbit monoclonal antibodies available for detection of various carcinomas. The c-Myc/immunoglobulin heavy-chain (IGH) fusion gene are seen in Burkitt lymphoma and diffuse large B-cell lymphoma, blastic mantle cell lymphoma and transformed follicular lymphoma. HER2 / ErbB2 is one of the four members of the ErbB receptor family of transmembrane receptor-like tyrosine kinases. Overexpression of ErbB2 is detected in almost 40% of human breast cancers.

Epitomics is the world leader in rabbit monoclonal antibody (RabMAb®) technology. Using our proprietary RabMAb technology, we have developed high quality antibodies (EP Clones™) and IHC kits (EpiPrecision™, EpiVision™) for anatomical pathology use.

For more information, contact us at 877-772-2622, IVDinfo@epitomics.com or visit our website at http://www.epitomics.com/diagnostics.

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22 December 2011: Ventana Medical Systems Inc., a member of the Roche Group, and Advanced Cell Diagnostics Inc. announce they have entered a worldwide co-promotion agreement for the first commercially available, fully automated RNA in situ hybridization (ISH) assay system capable of robust detection and visualization of virtually any expressed gene in routine clinical specimens at single-molecule sensitivity.

The two companies have partnered to automate this assay system on the VENTANA DISCOVERY series slide staining platforms. The product offerings are expected to become commercially available in the first quarter of 2012 and will initially be offered for research-use only applications.

“Given the fact that the majority of biomarkers are discovered from genomic research and are RNA by nature, the automation of RNAscope represents an important milestone that will accelerate biomarker research into a new level of sophistication,” said Dr. Yuling Luo, founder, president and CEO of ACD. “RNAscope will become an equally indispensable tool alongside immunohistochemistry, fluorescence in situ hybridization and polymerase chain reaction for researchers in life sciences and drug development.”

mRNA of Nav1.7, a sodium channel, expressed in normal mouse brain tissue detected by automated RNAscope XT assay. Single mRNA molecules (i.e. the individual dots of the hybridization signal) can be observed in the paraventricular hypothalamic nucleus on both neuronal cell bodies and dendrites. This image is taken with 100x objective lens.

RNA in situ hybridization is an indispensable method to analyze gene expression in the context of tissue architecture in areas of oncology, virology, and neuroscience research. RNAscope is an award-winning breakthrough technology that provides researchers the unique capability to interrogate the function and disease relevance of any expressed genes in situ, especially for the approximately 5,000 genes and 15,000 non-coding RNAs in the human genome where no other technologies can adequately address. In addition, RNAscope allows researchers to tap into the estimated 400 million clinically-annotated, archived formalin-fixed paraffin-embedded (FFPE) tissue specimens for retrospective clinical studies in translational research.

For more information, click here.

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19 December 2011: Leica Microsystems announces the availability of Leica ChromoPlex™ 1 Dual Detection for BOND, the first fully automated one-step detection system allowing the co-visualization of mouse and rabbit antibodies on a single slide. Same day diagnosis is now easier to achieve when compared with the two-step sequential or semi-automated processes currently available on competitive IHC advanced stainers.

“The dual staining obtained using the ChromoPlex 1 detection system is attractive, crisp and consistent; ideal when assessing challenging prostatic biopsies,” states Dr Geoffrey Hulman MD FRCPath, Consultant Histopathologist at Nottingham University Hospitals NHS Trust, where the detection technology was evaluated in cooperation with the Nottingham Health Science Biobank.

ChromoPlex 1 Dual Detection is a biotin-free, polymeric horseradish peroxidase (HRP)-linker and polymeric alkaline phosphatase (AP)-linker antibody conjugate system for the detection of tissue-bound mouse and rabbit IgG primary antibodies. The small multifunctional linkers enhance tissue penetration, producing high sensitivity. The excellent contrast between the Fast Red and DAB chromogens allows for easy antigen differentiation. ChromoPlex 1 Dual Detection for BOND is intended for staining sections of formalin fixed, paraffin-embedded tissue for use on Leica BOND-MAX and BOND-III automated IHC staining systems. It can be used simultaneously with both Novocastra BOND Polymer Refine and Polymer Refine Red Detection, allowing unparalleled flexibility in staining protocols and workflow efficiency.

For more information, click here.

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14 December 2011: Epitomics is pleased to showcase two EP Clones, ER alpha and PR, for high quality detection of Breast cancer. Estrogen Receptor Alpha (ER Alpha) is a nuclear protein and member of the steroid hormone receptor family. The human progesterone receptor (PR), is a ligand-activated transcription factor and is also a member of the steroid receptor family.

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13 December 2011: Leica Microsystems has announced the release of the Leica ASP6025, an advanced tissue processor for histology laboratories that is focused on improving quality, laboratory productivity and, most importantly, patient safety.

As well as providing the exceptional processing quality needed for accurate diagnosis, the Leica ASP6025 incorporates a range of innovative features for specimen safety. These include a battery backup system that protects the specimens even during a complete power failure and the simple addition of a glass window that allows a quick visual check of specimens during processing. Also, Leica RemoteCare remote 24 hour monitoring helps identify problems before they damage tissue.

Along with the specimen safety features, the Leica ASP6025 also helps modern laboratories ensure high-productivity while protecting staff. Its rapid processing capabilities ensure fast turnaround times while a host of productivity innovations reduce upkeep time. Laboratory staff can also breathe easily thanks to a xylene-free processing option, contact-free remote fill and drain, and a unique system that draws fumes away for the operator when the processor’s lid is opened.

For more information, click here.

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13 December 2011:. Clarient, Inc., a GE Healthcare company, and ACORN Research LLC announced today their strategic collaboration around molecular testing of tumor samples. The agreement will establish a standardized testing protocol across the ACORN network of oncology community practices and hospitals with treatment guidelines and clinical trial opportunities. These processes have the potential to improve oncology treatment and research that aim to deliver targeted treatments based on the specific genetic markers for each patient.

The collaboration will establish a system for the collection of a broad array of tumor-specific biomarker data at the time of the patient’s initial cancer diagnosis. Clarient’s expertise in cancer diagnostics, combined with ACORN’s oncology network and advanced bioinformatics platform, will enable the patient’s medical team to better determine the most effective treatment regimen for the patient’s tumor-specific biomarker profile. The Clarient-ACORN collaboration will also enable matching broad biomarker data with outcomes data from clinical trials and clinical practice to help identify new prognostic markers and biomarker-specific treatments.

For more information about Clarient, please visit www.clarientinc.com .

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8 December 2011: Modern Pathology, the official journal of the United States and Canadian Academy of Pathology (USCAP), announces the following free articles in its December 2011 issue:

Thyroid angioinvasion

Unusual angiomatoid fibrous histiocytomas

Inflammation and enteric CD10 expression

Modern Pathology's main focus is original papers reporting innovative clinical and translational research in the pathology of human disease. Access to all content is FREE 12 months post-publication. Visit the journal website at http://www.modernpathology.org.

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8 December 2011: Laboratory Investigation, the official journal of the United States and Canadian Academy of Pathology, presents the following free articles in its December 2011 issue:

Targeting SYK in glomerulonephritis

Beta-catenin in articular cartilage

Frataxin in astrocytic tumors

Laboratory Investigation is an international journal owned by The United States and Canadian Academy of Pathology and edited by a board appointed by the Council of the Academy. Laboratory Investigation offers prompt publication of high-quality original research in all biomedical disciplines relating to the understanding of human disease and the application of new methods to the diagnosis of disease. Visit us online at http://www.laboratoryinvestigation.org.

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4 December 2011: Leica Microsystems, a world leading provider of microscopy systems and total histology solutions, announced that it has acquired the microscopy and histopathology business of Labindia Instruments Pvt. Ltd., a leading solutions and service provider in India. This transition comes after more than 20 years during which Labindia has successfully distributed Leica’s products in India.

Leica also announces that Imperial College Healthcare NHS Trust, with one of the largest immunohistochemistry / in situ hybridization (IHC / ISH) workloads in the UK (120,000 IHC slides a year), has selected Leica Microsystems’ BOND platform to provide advanced IHC and ISH staining capabilities at its Hammersmith, Charing Cross and St Mary’s Hospital sites.

For more information, click here.

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11 November 2011: bioTheranostics, Inc., a bioMérieux company that develops innovative oncology diagnostic tests to drive personalized treatment, announces a clinical study that links CancerTYPE ID® molecular testing with improved patient outcome. Patients in which CancerTYPE ID predicted a colorectal site of origin that subsequently received site-specific therapy had a median survival three times that of what has been reported in patients treated empirically for cancer of unknown primary (CUP). These results make CancerTYPE ID the only marketed molecular cancer classifier to demonstrate therapeutic response and patient benefit based on molecular tumor profiling.

The study, led by John Hainsworth, MD, of the Sarah Canon Research Institute, A Retrospective Study of Treatment Outcomes in Patients with Carcinoma of Unknown Primary Site and a Colorectal Cancer Molecular Profile (Clin Colorectal Cancer 2011 Oct 13 [Epub ahead of print]), focused on the improved treatment response and survival in a group of patients in which CancerTYPE ID results were utilized in the selection of site-specific therapy. According to the study findings, which will be published in the December issue of Clinical Colorectal Cancer and currently are available online, 75 percent of the patients showed negative colonoscopy results, and approximately half the patients had atypical immunohistochemistry for colorectal cancer. Significantly, CancerTYPE ID was used as part of the routine work-up and site-specific treatment was selected based on the molecular assay prediction.

The study results demonstrated a 50 percent response rate in patients treated with first-line regimens for colorectal cancer versus only 17 percent in patients treated with current empiric therapies for CUP (P value = 0.0257). Patients predicted to have colorectal cancer by CancerTYPE ID and treated with colorectal cancer treatment regimens experienced a median survival of 27 months. In comparison, patients treated with empiric CUP treatment have historical median survivals ranging from 8 to 11 months.

For more information please contact Wendy Johnson, Associate Director Marketing, bioTheranostics, 858-587-5887 or click here.

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11 November 2011: The largest capture area of any line scanner in digital pathology is now possible with the Leica SCN400 and SCN400F. The latest release in Leica’s Total Digital Pathology portfolio enables the digitization of very large specimens, not possible with any other line scanning digital pathology system.

This development provides a new level of flexibility in digital pathology, enabling users to scan a wide range of samples on a single system. Traditional (26 x 76 mm), double (52 x 76 mm) and now extra-large Jumbo (113 x 76 mm) slides can all be captured in either brightfield or fluorescence using the Leica SCN400 and SCN400 F scanners.

Existing users of the Leica SCN400 digital slide scanner range can benefit from being able to implement large slide scanning, without any hardware changes or physical updates to their scanners.

To view some sample large slide scans, please visit our Virtual Slide Gallery by clicking here.

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11 November 2011: Epitomics is pleased to mark its 10th Anniversary as the source of Rabbit Monoclonal Antibodies! For a limited time, select EP Clones are now 50% OFF. View the full list here.

EP Clones are generated using our patented RabMAb® technology and have been validated for IHC use, offering superior binding affinity and specificity. Fully validated, ideal for FFPE tissues.

For more information, contact us at 877-772-2622, IVDinfo@epitomics.com or visit our website at http://www.epitomics.com/diagnostics/promotions/ivdanniversary.

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27 October 2011: Leica Microsystems announce the launch of its clinical workflow solution for Digital Pathology. Digital Image Hub Enterprise* with its powerful image management, integration and communication capabilities, in conjunction with a new high performance, intuitive client viewer, SlidePath Gateway*, combine to make this the ideal solution for clinical centers moving towards true Digital Pathology implementation. Furthermore, Leica's Total Digital Pathology solutions now provide an implementation of the DICOM Supplement 145 standard for both slide scanning and viewing.

Flexible case aggregation capabilities in Digital Image Hub Enterprise utilizes slide barcodes to identify and automatically consolidate multiple slides within a case into a worklist. The system can then automatically associate the slides with appropriate case information by querying the laboratory information management system (LIMS), thus presenting both case information and digital slides concurrently. These comprehensive and flexible communication specifications enable seamless integration of Digital Pathology with world-leading anatomical pathology LIS providers, such as Cerner CoPath PlusTM and Sunquest (formerly Elekta) PowerPath, as well as additional 3rd party and bespoke systems via the inbuilt flexible Integration Toolkit.

For more information, click here.

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27 October 2011: Epitomics Cyclin D1 is now available. Rabbit monoclonal antibodies to cyclin D1 showed the highest sensitivity to detect this antigen in formalin fixed paraffin embedded tissue as compared to several other clones. For more information on this antibody, click here.

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27 October 2011: BioGenex Laboratories announces the launch of a new company website that allows customers easy navigation to search for products and find technical solution. The newly launched BioGenex website is a customer-focused information center to provide customer with knowledge, training, solution, and products they can use to achieve their best pathology lab results.

“Researchers can easily find what we offer, what are new, and FREE samples they can try out for their work. Meanwhile, they can visit our knowledge center to see how our products and protocols have been used to help researchers” said Krishan Kalra, CEO of BioGenex Laboratories.

Visit Biogenex at www.Biogenex.com.

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11 October 2011: Modern Pathology, the official journal of the United States and Canadian Academy of Pathology (USCAP), announces the following free articles in its October 2011 issue:

VEGFA gene amplification in colorectal cancer

Oropharyngeal undifferentiated carcinoma

HuR, COX-2 and survivin in lung carcinomas

Modern Pathology's main focus is original papers reporting innovative clinical and translational research in the pathology of human disease. Access to all content is FREE 12 months post-publication. Visit the journal website at http://www.modernpathology.org.

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11 October 2011: Laboratory Investigation, the official journal of the United States and Canadian Academy of Pathology, presents the following free articles in its October 2011 issue:

Role of hemidesmosome in invasive SCC

Disease-defining translocation in nodular fasciitis

miRNA-148a suppresses tumor formation by targeting CDC25B

Laboratory Investigation is an international journal owned by The United States and Canadian Academy of Pathology and edited by a board appointed by the Council of the Academy. Laboratory Investigation offers prompt publication of high-quality original research in all biomedical disciplines relating to the understanding of human disease and the application of new methods to the diagnosis of disease. Visit us online at http://www.laboratoryinvestigation.org.

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11 October 2011: Leica Microsystems announces that its Knowledge Portal for Microscopy and Histology is online. Leica Science Lab (http://www.leica-microsystems.com/science-lab) offers scientific research and teaching material on the subjects of microscopy and histology, from the basics to specific application know-how.

Illustrated and interactive tutorials as well as white papers explain technical rudiments all the way from specimen preparation and immunochemistry to imaging, contrast techniques and high-end technologies such as super-resolution. In addition, Leica Science Lab features scientific articles on special techniques, applications and areas of research. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. What’s more, the range of topics offered by the portal will be continuously widened.

Leica Science Lab invites its readers to discuss the articles and topics presented. Users’ comments and questions will be used to improve the information on an ongoing basis. At the time of the official go-live date, 100 authors had contributed to filling the portal with in-depth content. Experts in science, methods, and techniques who would like to share their knowledge with the community are cordially invited to pub¬lish their articles in Leica Science Lab.

For more information, click here.

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26 July 2011: OPTRONICS® presents a case study about High Definition Hematology. In 2009, the Royal Berkshire Hospital (RBH) made the decision to update its microscope camera system. Located in the Haematology Department, the equipment originally consisted of a microscope mounted analogue video camera connected to a 21-inch professional monitor. This was used for presentations and training purposes for over ten years until it started to fail and display picture defects. Click here to read the short article.

For more information, contact Rich Crandall, Director of Business Development at 805.562.3980 or rcrandall@optronics.com, or visit us online at http://www.optronics.com.

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25 May 2011: Milestone Introduces MacroVIEW DM, a mobile digital imaging evolution for modern autopsy, necropsy and forensic investigations. The MacroView DM builds on our over 15 years of digital imaging experience by dramatically improving the standardization and documentation of pathology procedures. It capture images of whole bodies, body parts and large organ systems. You can add visual or audio annotations to the images and also record video to create a more descriptive record of the autopsy, necropsy or forensic case. MacroVIEW DM can be connected via Internet to share all relevant information of the autopsy/necropsy procedures with remotely located pathologists through the new MileVIEWER software package.

For more information, call 866-995-5300, email info@milestonemed.com or click here.

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29 April 2011: An article in the January 2011 CAP Today discussed Voicebrook’s leadership in the Pathology speech recognition arena. The article focuses on the role of speech recognition software for laboratory transcription, and indicates that Voicebrook’s VoiceOver software is the only speech recognition product that is designed for pathologists. Features important for Pathologists include advanced templating, discrete data entry and CAP Cancer protocols, a knowledge base of Pathology templates, hands-free microphone and foot pedal integration, delegated and digital dictation workflows, custom integration with over 16 AP/LIS products, downtime procedures, integration with Digital Imaging platforms, and customized vocabulary and functionality to handle unique Pathology reporting workflows.

For more information, please visit http://www.voicebrook.com or click here to read the article.

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11 April 2011: SPOT Imaging Solutions announces the launch of the new 2011 PathWall. The PathWall has been designed specifically to meet the needs of the pathology lab for bench top documentation of dissections. The PathWall is a complete turnkey system that includes all the mounting accessories, imaging equipment, computer controller and software to provide smooth, task oriented workflow. Features include hands-free zoom, focus and image capture with on-screen section lines, block labels, regions of interest and even measurements. The PathWall makes documentation of the gross dissection so easy and routine that every case can be documented from receipt of containers, through documentation received samples to full annotation and auto-saving to your laboratory file server or LIM system.

For more information on the PathStand 24 and other SPOT PathSuite products, please contact us at 1-866-604-SPOT (7768) or visit us at www.spotimaging.com/pathsuite

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26 January 2011: ARUP’s Online Scientific Resource for Research and Education provides more than 20 free CME courses for physicians. Course topics reflect current issues and developments in pathology; new courses are added monthly. This resource is provided by ARUP’s medical directors, who are faculty at the University of Utah School of Medicine, along with other highly qualified expert contributors.

The University of Utah School of Medicine designates these educational activities for AMA PRA Category 1 credit(s) and affirms that they meet the criteria for Self-Assessment Modules (SAM) credit to apply toward the Maintenance of Certification (MOC) by the American Board of Pathology.

For more information, click here.

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4 October 2010: Elekta (booth #618) introduced the latest release of the PowerPath™ anatomic pathology Laboratory Information System (LIS), featuring the fully integrated Advanced Materials Processing (AMP) feature at CAP ’10. This feature greatly enhances laboratory workflow solutions for histology and cytology specimens, improving pathology lab efficiency and reducing errors. PowerPath’s integrated case materials tracking and management feature uses bar code technology. Case materials are tracked from the point of accession through processing and diagnosis to filing or discard.

PowerPath’s case materials tracking and management feature improves patient safety by enforcing the link between the material and the case record. Each time a specimen, block, slide or vial is scanned, PowerPath displays identifying information, such as patient name or case number, reducing the likelihood the user will process the wrong material or select an incorrect patient.

For more information, contact Stina Thorman, Vice President Corporate Communications, Elekta AB, +46 8 587 254 37, tina.thorman@elekta.com, Time zone: CET: Central European, or Michelle Lee, Director, Global Public Relations and Brand Management, Elekta, 1-770-670-2447, michelle.lee@elekta.com, Time zone: EDT: Eastern Daylight, or click here.

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7 May 2010: PSA is proud to announce its new innovative pathology coding website, www.PathLabCoding.com! PathLab Coding Solutions is designed to provide education and training to help improve report documentation and CPT coding skills, in order to minimize risks associated with over-coding, under-coding and insufficient documentation. Subscribers to this service will have the advantage of consulting with PSA’s certified professional coders, accessing automated or online CPT coding resources, and receive written responses to your coding questions and concerns. CAP members have the opportunity to subscribe at a discounted rate!

PSA, a MED3OOO company, offers pathology practices and clinical laboratories an integrated approach of billing and collection services, practice marketing support, coding compliance services, and preferred pricing on pathology products and services.

To learn more about PathLab Coding Solutions, visit http://www.pathlabcoding.com or contact Leigh Polk with PSA at 800.832.5270 ext 2941 or lpolk@psapath.com.

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18 June 2009: Photodyne Technologies is a manufacturer of specialized photographic machines for use in grossing, pathology and forensic labs, and other macro photography applications. Our new macro-photography and grossing units have an optional low voltage D.C. operation, for enhanced safety. The units are supplied with top of the line digital cameras, with resolution of 8 to 15 megapixels and higher. The system comes with proprietary software and connects directly to the user’s computer through a USB port, allowing the user to take pictures directly from the computer in real time, with adjustments in the scene as necessary. All major attributes of the camera are controllable from the computer as well.

Once the picture is snapped, the data are transferred to the hard drive through the USB port and stored in the user’s specified location, and the pictures are then ready to be used for lectures and presentations, archiving, email attachments, research and more.

Visit us online at www.photodyne.com or contact us at 800-660-2147 or hrzc@earthlink.net for more information.

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10 February 2009: Covance is pleased to announce the availability of Collagen XVII antibody. Collagen XVII (BP180) is a transmembrane protein of the cutaneous basement membrane that plays an important role in epidermal-dermal adhesion. It has been associated with inherited bullous skin disease and autoimmune disease, and may also play a role in trophoblast invasion. The launch of Collagen XVII adds to Covance’s growing portfolio of antibodies and detection chemistries.

For more information, please visit www.covance.com.

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10 February 2009: Vachette Pathology is proud to announce its newly improved website Vachettepathology.com. The website will have more content and more information. The goal of the website will be to concentrate all the knowledge and experience we have into a single database that is more useable for both our current and potential customers.

Vachette Pathology is a practice management firm that specializes in pathology. Currently we work with over 450 pathologists nationwide and are commonly held as the industry leaders in the business of pathology and laboratory management.

If you have any questions or for further information, please contact Mick Raich toll free at 866-407-0763, or email mraich@vachettepathology.com

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10 September 2008: Sakura announces The Tissue-Tek® Xpress® x50. The Tissue-Tek® Xpress® x50 delivers unprecedented productivity and maximizes staff efficiency. The Tissue-Tek® Xpress® x50 processes up to 440 specimens in an 8-hour shift, with the ability to load up to 40 cassettes approximately every 45 minutes. It provides outstanding time and cost savings, as well as increased staff safety, while producing standardized, accurate results paralleling those from overnight processing, allowing same-day diagnosis and, ultimately, improved patient care.

For more information, visit us online (click here), write to mail@sakuraus.com, or call 1-800-725-8723 and press 1 for customer service.

End of New Products and Services page