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13 November 2009: Thanks to (1) Dr. Suhail Muzaffar, City Hospital, West Midlands, UK, for contributing images of normal duodenum for our Small Bowel chapter; (2) Dr. Guido Nicolò, Genova, Italy, for submitting images of Enterobius vermicularis eggs for the Cervix-Cytology chapter.

26 October 2009: We have updated the Mystery Case.

20 October 2009: We have completed our update of the Breast Malignant chapter. 

25 September 2009: Thanks to Dr. Asmaa Gaber Abdou, Menoufiya University, Egypt, for contributing images of Follicular Adenoma-Trabecular type in the Thyroid chapter.   Thanks to Angel Fernandez-Flores, MD, PhD, Hospital El Bierzo & Clinica Ponferrada, Ponferrada, Spain, for contributing images of Bullous Pemphigoid for the Skin non-tumor chapter.

12 September 2009: Be sure to check the special sections on our Jobs page, under Miscellaneous, for Locum Tenens / Part-time jobs, PhD positions, Seeking a Residency or Residency Positions available, Job Advice and an article on Transitioning.

7 September 2009: We have updated the in situ carcinoma section of the Breast-Malignant chapter.

27 August 2009: Thanks to Dr. Asmaa Gaber Abdou, Menoufiya University, Egypt, for contributing images which we added to our PathologyOutlines.com Flickr group pool.  We’ve added links in the Uterus chapter to his pictures of Dysfunctional Uterine Bleeding.

26 August 2009: Thanks to John Irlam, D.O., University of Toledo Medical Center (Ohio), for contributing images to our PathologyOutlines.com Flickr group pool. We’ve added links in the Skin-Nonmelanocytic tumors chapter to his pictures of Cylindroma, Trichilemmoma, Sebaceous Hyperplasia, Eccrine Poroma and Sebaceous Carcinoma, as well as links in the Skin-Melanocytic tumors chapter to his images of Blue Nevus.

Thanks to Ed Uthman, MD., Texas, for allowing us to add links to these Flickr images: Cervix chapter - Squamous Cell Carcinoma, Lymphomas: B cell chapter - Burkitt’s Lymphoma,  Oral Cavity chapter - Infectious Mononucleosis and Placenta chapter - Incomplete / Partial Hydatidiform mole.

14 August 2009: We have updated the Smooth Muscle section of our Soft Tissue Tumors - Part 3 chapter.

28 July 2009: We now have a PathologyOutlines group on Flickr. If you have a Flickr account, you can upload directly to our Flickr group at http://www.flickr.com/groups/pathologyoutlines/. We will post your name as the contributor (unless you want to be anonymous) and a link to them in the appropriate chapter of our online textbook, so pathologists and related personnel throughout the world can benefit from them. 

24 July 2009: We have updated the Skeletal Muscle section of our Soft Tissue Tumors - Part 3 chapter.

23 July 2009: Thanks to Dr. John Irlam, University of Toledo Medical Center, for contributing images of nodular melanoma to the Skin-Melanocytic Tumors chapter.

18 July 2009: We have updated our Mystery Case, on the right side of the Home Page below the banners. We hope to update it every 1-2 months.

17 July 2009: We want to make it easy for you to fill all of your laboratory positions, so we have created a special low rate for advertising. The cost is only $1000 (US dollars) for up to 5 ads posted within one year. This means that you can post a new ad every 2-3 months for one low rate. These ads include pathology assistants, blood bank technicians, medical technologists, managers and all positions associated with the lab, but not pathologists or PhD positions. One ad can offer multiple positions. Click here for more details.

12 July 2009: We have now posted the Skin-Melanocytic Tumors chapter in our new format. We have also posted these new / revised markers in the Stains chapter: HE4 (serum marker for ovarian carcinoma), Oscar Keratin (wide-spectrum keratin) and GCDFP-15 (marker of apocrine function). We are starting to update Soft Tissue Tumors 3 - Muscle, Vascular, Nerve, Other.

9 July 2009: Thanks to Dr. Angel Fernandez-Flores, Hospital El Bierzo and Clinica Ponferrada, Spain, for contributing images of folliculitis decalvans for the Skin-nontumor chapter under Alopecia.

1 July 2009: Thanks to Jennifer Stumph, MD, Spectrum Health, for contributing images of schistosomiasis to the Parasitology chapter.

29 June 2009: We have started to apply our new format to the Stains chapter, and have extensively updated the topics on BG-8 (useful for mesothelioma) and D2-40 (a marker of lymphatics). For many stain topics, we now include a link to a company that supplies these markers (for example, Covance for these markers). This feature was suggested by a visitor, who noted that many pathologists, after reading about a marker, want to know where they can get it.

19 June 2009: We have updated Soft Tissue Tumors-Part 2 (click here), which includes Fibrohistiocytic and Adipose tissue tumors. This chapter is also in our new format, in which each topic is a separate page that is accessed by clicking on the link in the Table of Contents or Index. The advantages are faster loading of each page, easier to read pages with less scrolling, and the inclusion of thumbnails for most of the 600+ images. We still have to decide how to create a printer friendly version - our current thinking is to have it include all topics in the chapter, instead of having a separate printer friendly version for each topic, but let us know what you think. 

12 June 2009: Congratulations to Dr. Alireza Zarineh, Allegheny General Hospital, Pennsylvania (USA). She also received a check for $50 for completing our survey and being the second winner of our drawing. We will announce a new contest / drawing at the end of the summer.

11 June 2009: If you do DermPath, please note that we have extensively updated the Books pages at www.DermatologyOutlines.com. We try to include all DermPath books at both sites, but non-pathology books for dermatologists are only listed on DermatologyOutlines. It also has advertisements for Dermatology related Jobs, Fellowships and Conferences that may not be posted at PathologyOutlines, since the advertiser decides where to post the ad.

5 June 2009: Congratulations to Dr. Roopa Paulose, Hatton Health, United Kingdom. She received a check for $50 for completing our survey and winning our drawing. Thanks to all who completed the survey, which helps us improve our website.

4 June 2009: We added a category to the Pathology Jobs page - Buy/Sell pathology practices/labs. Our first advertiser wants to buy practices or laboratories in any of five states.

We are changing the format of our textbook so each topic has a separate page. The advantages are (a) easier to read, (b) ability to include thumbnails of images, (c) better targeting of search engines to the correct topic, (d) pages will load faster with less scrolling. To view a sample page, click here, and let us know what you think.

1 June 2009: We have reformatted the chapters on the Home Page to reduce the amount of scrolling necessary. We are also planning other steps to make our website easier to use, based on your suggestions, so let us know what you think!

29 May 2009: We have split the Soft Tissue chapter into 3, and updated Part 1, which discusses Introduction, Infections & Fibroblastic / myofibroblastic tumors (click here). New features to be incorporated into all chapters as they are updated, include an additional table of contents sorted alphabetically, new formatting and more discussion of differential diagnoses.

Thanks to Angel Fernandez-Flores, MD, PhD, Hospital El Bierzo and Clinica Ponferrada, Spain, for contributing images of botryomycosis to the Skin-nontumor chapter and acquired digital fibrokeratoma to the Skin-nonmelanocytic tumor chapter.

19 May 2009: Thanks to Dr. Steven Catinchi-Jaime, for contributing images of a mixed Squamous Cell Carcinoma-Malignant Fibrous Histiocytoma arising in the vocal cord, which were posted in the Squamous Cell Carcinoma section of the Larynx chapter.

18 May 2009: We added two new articles to our Management Page - How the New Anti-Markup Rules May Change Your Practice, by Michelle Miller and Mick Raich, Vachette Pathology (click here) and FTC "Red Flags" Rule Compliance, by John R. Outlaw, PSA, LLC (click here). You can also access the Management Page from the center section of our Home Page.

15 May 2009: We added information on the Hansel stain to the Stains chapter. It is used to detect eosinophils in urine. We have reformatted the clinical pathology topics on our Home Page, to make them easier to access.

12 May 2009: Thanks to Angel Fernandez-Flores, MD, PhD, Hospital El Bierzo and Clinica Ponferrada, Spain, for contributing images to the Skin-Melanocytic Tumors chapter of blue nevus, cellular blue nevus, dysplastic nevus, lentigo melanoma and melanoma-general.

30 April 2009: The Breast-Malignant chapter was reviewed by Dr. Daniel Visscher, University of Michigan.

29 April 2009: We added a new article to our Management Page - Coding Prostate Saturation Biopsies, by Laura Edgeworth, PSA, LLC. Click here for the article or you can access the Management Page from the center section of our Home Page. Our Thyroid chapter, which was recently extensively updated, has been reviewed by Shahidul Islam, MD, PhD, Director of Cytopathology, The Ottawa Hospital, Ontario, Canada.

20 April 2009: We added a new article to our Management Page - Billing Contracts verses Managed Care Contracts, by Mick Raich, Vachette Pathology. Click here for the article or you can access the Management Page from the center section of our Home Page.

Do you have good examples of Ovarian-nontumor pathology? Help your fellow pathologists worldwide by contributing these images to PathologyOutlines.com, where they will be viewed on a regular basis. The images particularly needed are indicated by clicking here.

16 April 2009: We have extensively updated Kidney tumors, and split the topic into two smaller chapters, which will now be updated annually:

Kidney tumor - cysts, children, adult benign
Kidney tumor - adult malignancies

These chapters have two tables of contents - one sorted in the usual manner and one in alphabetical order. Each chapter now has hundreds of images from the AFIP fascicle - third series, which include the description as part of the image. For some images, you should click on the image once to enlarge it to read the descriptions more easily. We also added many other new images and references, more spacing to improve readability, and more text labels. Let us know if you have any comments.

15 April 2009: We have added a new Management Page article - CMS Continues to Tinker with Anti-Markup Rule, POD Labs and In-Office Histology Labs in the Cross-Hairs, by John Outlaw, PSA, LLC. Click here for the article or you can access the Management Page from the center section of our Home Page. We have updated our list of Top Books sold through our website at Amazon.com. Number one is Fenoglio-Preiser: Gastrointestinal Pathology. Click here for the list, or click on the Books button on the left hand side of the Home Page.

30 March 2009: The Breast-nonmalignant chapter has been reviewed by Dr. Hind Nassar, Johns Hopkins Medical Institutions. We have added a new Stains topic - B72.3. However, we need more images of this immunostain for various tumors - please email them to us if available. We apologize for broken links, which are due to changes in other websites. For example, Modern Pathology, The Internet Journal of * * * (various titles) and the Digital Atlas of Breast Pathology have all changed some of their links, which caused our links to not work. We fix broken links when we find out, but we don’t always find out right away. To minimize this problem, please send us images that you have of any relatively uncommon disorders. We will list your name as a contributor, and will store the images on our server with stable links.

16 March 2009: Thanks to those who found our booth hidden between two huge islands at USCAP. As a result of the feedback, we will be updating chapters at a faster pace, adding legends to AFIP images and improving the formatting of our chapters.

We updated the Thyroid chapter with additional images and references. The Soft Tissue-Part 1 chapter has been reviewed by Dr. David Lucas, University of Michigan Medical Center, and we have incorporated his suggestions. We added a new Management Page article, “The New Year Offerings”, by Mick Raich, Vachette Pathology.

13 February 2009: We have completed our update of the Ovary-nontumor chapter, which has 46 topics, 200 images (many from the AFIP fascicle, 3rd series) and 250 references. We have also added a section on FISH to the Molecular Pathology chapter, written by Dr. Rodney E. Shackelford of Johns Hopkins.

2 February 2009: Congratulations to Drs. Marilin Rosa, Jacksonville, Florida and Angel Fernandez-Flores, Ponferrada, Spain for winning our Amazon.com drawing. Each received a check for $50 for purchasing items through our website from Amazon. Dr. Fernandez-Flores donated her winnings to our charity, The Detroit College Promise. Congratulations also to Dr. Andrea L. Weins, Ball Memorial Hospital, Indiana, for winning our drawing for first year residents who signed up for our New Books email. She also received a check for $50.

We have added a Product Placement advertising feature. For antibodies, stains or molecular markers, at the end of the text for that marker you may see, "Sources for testing (advertisements): company name". This is a link to an advertisement for this product. This feature was requested by pathologists, who want to know how to purchase specific products, and the advertising revenue helps support our free website.

We will be at booth #711 at USCAP in Boston on March 9-11 (Dr. Pernick will be at the booth only the first 2 days). Stop by and say hello, and let us know your thoughts on how we can make our website more useful to you.

1 December 2008: (a) We extensively updated the Skin-Melanocytic Tumors chapter, now with 450+ image links (many links are to multiple images), including clinical, dermoscopic and microscopic images. There are also 500+ references from the most current literature. (b) We posted new Management Page articles, “The Tangled Web of Claim Payments-How Managed Care Contracts Kill Your Revenue” and “Hospital Outreach Laboratory For Sale. Who’s Buying Now?”, both by Mick Raich, Vachette Pathology. (c) We started posting Board Review questions (the button is on the left hand side of the Home Page). We will organize them by category as the numbers increase. (d) The winners of our Laboratory Job email contest were Loretta Pasillas, Cedars-Sinai Medical Center (California) and Anthony Sellner, Quinnipiac University (Connecticut), who each won $50. Thanks to all who signed up for our laboratory (non-pathologist) email list. (5) Thanks to the following contributors of images to these chapters: Dr. Derek Mathis and Dr. Rosemarie Rodriguez from the SAUSHEC Pathology Residency Program, San Antonio, Texas: Small Intestine - Whipple’s disease; Drs. Michael P. Orejudos and Rosemarie Rodriguez, SAUSHEC, San Antonio, Texas (USA) -Lung nontumor - CMV; Dr. Semir Vranic, University of Sarajevo, Bosnia and Herzegovina - Ampulla - adenocarcinoma; Angel Fernandez-Flores, MD, PhD, Hospital El Bierzo and Clinica Ponferrada, Spain, Skin-nontumor - fat necrosis (acute pancreatitis); Skin-Melanocytic tumors - junctional nevus, dermal nevus - Unna’s type, Spitz nevus.

27 October 2008: (a) We posted a new article on our Management Page - “Pathology takes another pay cut”, by Mick Raich, Vachette Pathology. (b) Our Jobs-Other page now includes Sales jobs relating to Pathology. (c) We have updated the Breast-nonmalignant chapter with new text, references and over 400 new image links. This is one of our most popular chapters (also Soft Tissue part 1, Thyroid, Ovary, Breast malignant, Kidney Tumor, Skin Tumor, CNS Tumor, Uterus, Skin nontumor, Soft Tissue part 2 and Stains), and our goal is to update these chapters at least once a year. We will try to update the remaining chapters at least every 2 years, and more frequently if possible. We will still add new Clinical Pathology topics and plan to add 1000 image links per month. (d) We are updating the Stains chapter with the most commonly used stains, in alphabetical order. We recently updated these topics: Acid Fast Bacilli, Actin-muscle specific and Alpha-1-antitrypsin. Our philosophy is to post information about stains based on published research. We do not believe it is good science to routinely combine studies of immunostains, without a thorough understanding of the methodology of the studies. Different studies often use different antibody clones, different dilutions and markedly different methods of interpretation. (e) As we update new chapters, most of the image and reference links will now open a new window, which was requested by our visitors.

13 October 2008: (a) By request, we started a new Fellowships email. Every 2 weeks, we will email subscribers a list of new fellowships posted at our website. To subscribe, email NatPernick@Hotmail.com with “subscribe to Path fellowships email” in the subject line. (b) By request also, we will add a section on Board Review Questions. If you have sample questions and answers, just email them to us. We will post a Board Review button on the left hand side after we get 5 questions. (c) We thank Dr. Asmaa Gaber Abdou, Menofiya University, Egypt for contributing images of poikiloderma atrophicans vasculare to the skin-nontumor chapter.

8 October 2008: (a) We have a new contest / drawing for first year pathology residents in the US or Canada who sign up for our New Books email by 31 December 2008. Just email NatPernick@Hotmail.com with “sign up for new books email” in the subject line, and tell us the name of the program where you are a first year resident. We will select one name at random, and mail the winner a check for $50 (your status as a first year resident is subject to verification). (b) We moved to bigger offices next door, with a new fax number (248/646-3119) and suite (#408). (c) We thank the following contributors of images to the Chapters indicated: Dr. Asmaa Gaber Abdou, Menofiya University, Egypt - Testis - yolk sac tumor metastatic to abdomen, germ cell aplasia-Sertoli cell only, Leydig cell hyperplasia, normal testis and spermatocytic arrest; Dr. Nilesh N. Patel - histoplasmosis of stomach.

9 September 2008: (a) We have updated the Breast-Malignant chapter, now with 1300+ image links and new references and text. (b) We are seeking authors to write new chapters on quality assurance / quality control in the laboratory, or flow cytometry. If interested, please contact Dr. Pernick at NatPernick@Hotmail.com. (c) Our Thyroid Gland chapter was reviewed by Shahidul Islam, MD, PhD, FCAP, The Ottawa Hospital, Ontario (Canada). (d) We added a new related website, DermatologyOutlines.com. Be sure to tell your dermatology colleagues about it. (e) We added a new Management page article, Collaborative Labs and the Underlying Cost to Pathologists, by Mick Raich, Vachette Pathology. (f ) We have posted new images in the indicated chapters by these contributors: (i) Semir Vranic, M.D., University of Sarajevo, Bosnia and Herzegovina, Small bowel - metastatic melanoma to jejunum; (ii) Dr. Yao-Wen Liu, Kuo General Hospital, Taiwan, Cervix cytology - cornflakes; (iii) Angel Fernandez-Flores, MD, PhD, Hospital El Bierzo and Clinica Ponferrada, Spain - Skin tumor - angiokeratoma, atypical fibroxanthoma, chondroid syringoma, glomeruloid hemangioma, glomus tumor, halo nevus, hidradenoma, hidrocystoma, lymphomatoid papulosis, vascular leiomyoma; Skin nontumor - cutaneous focal mucinosis, molluscum contagiosum, porokeratosis, psoriasis, Sweet’s syndrome, tuberculosis; (g) visit us at the AAPA, CAP or ASCP.

28 August 2008: We thank the following contributors of images to these chapters of our online textbook: (1) Dr. Mowafak Hamodat, Eastern Health of Newfoundland and Labrador, St. John’s, Canada - cervix - breast lobular carcinoma metastatic to cervix; uterus - leiomyoma, adenomyosis, leiomyoma embolization; testis - Leydig cell tumor; (2) Dr. Semir Vranic, University of Sarajevo, Bosnia and Herzegovina - small bowel - gall bladder carcinosarcoma metastatic to SI; breast malignant -solid variant of adenoid cystic carcinoma; (3) Dr. Nilesh Patel, California - esophagus - esophagitis, mixed herpes and candida; (4) Dr. Asmaa Gaber Abdou and Dr. Mona Kandil, Menofiya University, Egypt - skin-tumor - pilomatrixoma; ovary - MMMT; parathyroid - parathyroid adenoma; (5) Dr. Asmaa Gaber Abdou and Dr. Nancy Asaad - skin-tumor - hobnail hemangioma and fibrous papule of face; (6) Dr. Hanni Gulwani, New Delhi (India) - lung tumor - hamartoma; (7) Professor D. Y. Cohen, Herzliyah Medical Center, Israel - adrenal gland - retroperitoneal ganglioneuroma; (8) Dr. Julia Braza, Beth Israel Deaconness Medical Center, Boston, Massachusetts - skin-nontumor - molluscum contagiosum; breast malignant - CLL/SLL; (9) Professor Venna Maheshwar, Drs. Kiran Alam and Anshu Jain, J. N. Medical College, India - testis - filiarial epididymitis; nasal cavity - rhinosporidiosis; lung nontumor - aspergillosis; ear-otomycosis, skin nontumor - leishmaniasis, maduramycosis; (10) Dr. Angel Fernandez-Flores, Hospital El Bierzo, Ponferrada, Spain - skin-tumor - syringoma, trichoepitheliom; (11) Dr. Debra Zynger, Northwestern University, Chicago, Illinois - ovary - yolk sac tumor.

11 June 2008: By request, we have changed the Home Page banner links to open a new window. We have also changed the directories for the Jobs, Conference and Fellowship pages, so please rebookmark these pages if necessary. The old links will still work. We have started linking to some very nice images from Wiley publications, including cytology images. Unfortunately, after clicking on the image link, to see these images (which have a URL beginning Wiley) you may also have to refresh the screen.

29 May 2008: (a) We completed an extensive update of Soft Tissue Tumors-Part 1, now with 104 topics, including an introductory section about approaches to diagnosis, syndromes, grading and molecular patterns. We describe all WHO tumors and numerous non-WHO entities classified as fibroblastic / myofibroblastic, fibrohistiocytic and lipomatous, with over 1000 image links from the AFIP fascicle 3rd series, free full text journals and other sources, as well as 700+ references and 49 virtual slides. (b) Thanks to participants in our survey, and congratulations to Cheryl Rimmer, New Jersey (USA) and Serdar Balci, Ankara, Turkey, for each winning $75 for our survey related drawing. Our next contest/drawing will be this fall. (c) We added Seeking Employment and Seeking a Residency ads to our popular Jobs page. These ads run for 6 months and cost $500, which must be prepaid. (d) Thanks to contributors of images recently posted: bladder schistosomiasis (bladder and parasitology chapters) - Drs. Kiran Alam, Anshu Jain, Veena Maheshwari, Farhan A. Siddiqui and Ershadul Haq, J.N. Medical College, India; micropapillary HG PIN of prostate - Dr. John Irlam, University of Toledo, Ohio, inflammatory cloacogenic polyp (Anus) - Dr. Yvonne Bury, University Hospital of North Durham, UK, lipomatous hemangiopericytoma (Soft Tissue Tumors Part 1) - Dr. David Cohen, Israel.

15 May 2008: Our Buyer’s Guide now has a list of our advertisers - please contact your vendors who are NOT listed, and suggest that they advertise on our website. We added an article “Cardiac Autotransplantation for Surgical Resection of a Primary Malignant Left Ventricular Tumor”, sent by Dr. Jerad Gardner, The Methodist Hospital, Houston, Texas (USA) to the Heart-Tumor chapter. We added images of Burkitt’s lymphoma of the ileocecal value, contributed by Dr. Kaveh Naemi, University of California, Irvine, to the Lymphoma-B cell and Small Bowel chapters. We now have a Mystery Case of the Month on the Home page, right side. Click on the image to enlarge it, and on the link for the diagnosis.

7 April 2008: We have updated the Thyroid Chapter, which now has 111 topics in 44 pages of text, with 1017 image links and 760 references. For all chapters, we now have over 20,000 image links. Our Management page has 2 new articles from PSA - “Congress Delays Fee Schedule Cuts 6 Months - Or Not?” and “Dissecting the Physician Quality Reporting Initiative (PQRI)”. We thank the following contributors of images: (1) Dr. Julia Braza, Beth Israel Deaconess Medical Center, Boston, Massachusetts ([ALL with t(9;22)], (2) Dr. Hind Nassar, Johns Hopkins Medical Institutions, Maryland - breast adenoid cystic carcinoma-solid variant, (3) Dr. Asmaa Gaber Abdou, Menofiya University, Egypt - cervical lipoleiomyoma and (4) Dr. Marilin Rosa, University of Florida (USA) - ADH involving areas of sclerosing adenosis in a complex sclerosing lesion.

6 March 2008: (1) Thanks to all who visited our booth at USCAP '08. (2) To search our website, use the Google search boxes at the top or bottom of the Home Page - the search box at the bottom has the "cache" feature. (3) To search for text on any particular page, use Control F, which generates search boxes at the upper right in Internet Explorer and at the lower left with Firefox. (4) Click on the Contest button at the bottom of the Home Page to learn about our contest/drawing from those who complete our survey by 30 April 2008. (5) Finally, we now post administrative jobs related to Pathology on the Jobs-Other page.

22 February 2008: (a) We have a new contest / drawing for those who complete our new Survey by 30 April 2008. Click on the Contests button at the bottom of the Home Page or click here for more details. (b) We have updated the Stains chapter entry on calretinin. (c) We thank Dr. Julia Braza, Beth Israel Deaconness Medical Center, Boston, Massachusetts (USA) for sending us a case report on CLL with meningeal infiltration, which was posted in the Lymphoma-B cell chapter. (d) Stop by our Booth #514 at USCAP, March 3-5, 2008, and say hello!

22 January 2008: We added a new chapter, Chronic Myeloid Neoplasms, which incorporates the WHO 2008 classification to be published in a few months. It includes updated text and extensive images and references for Myelodysplasia, Myeloproliferative Neoplasms, MDS/MPN and Mast Cell Disease. We thank Dr. Hind Nassar, Johns Hopkins Medical Institute, for reviewing the Breast nonmalignant chapter. We thank the following contributors of images to the chapters indicated: Dr. Yan Lemeshev, Texas (USA)-Placenta (decidual vasculopathy), Dr. Monica de Baca, South Dakota (USA)-Parasitology (malaria), Leica Microsystems, Biosystems Division (Australia)-Stains F-Z (kappa and lambda ISH), Dr. Jamie Shutter, Florida (USA)-Lung nontumor (histoplasmosis), Drs. Charles J. Sailey, Borislav A. Alexiev and John C. Papadimitriou, Maryland (USA)-CD Markers CD100-CD400 (CD163) and Lymph Node-not lymphoma (histiocytic sarcoma), Dr. Hanni Gulwani, New Delhi (India)-Pancreas (serous cystadenoma), Ovary (juvenile granulosa cell tumor) and Lung nontumor (hydatid cyst).

14 January 2008: We have updated the Leukemia-Acute chapter, which now contains more discussion, images and references based on the new WHO classification for AML and ALL. Visit the Management Page (under Clinical Pathology Outlines) to read the new article "Pathology Practice Management Issues for 2008", by Mick Raich of Vachette Pathology. Finally, click on our new Contribute button to learn how you can help improve our website for the pathology community worldwide by contributing images, videos or comments.

7 January 2008: We are changing our contact email addresses to NatPernick@Hotmail.com and NatPernick@gmail.com. Please update your records. We now have an Available Candidates section on the Pathologist / PhD Jobs page, for those who want employers to contact them. The cost is $500 for posting up to 6 months, which must be prepaid.

13 December 2007: We have split the Breast chapter into two, and extensively updated the Breast-nonmalignant chapter. It now includes updated text, images and references on almost all nonmalignant breast entities. Let us know if we missed anything. We also added links to videos describing slide review. Our December 2007 monthly website news (click here) discusses changes to the Jobs page for 2008 and changes to our Reviewers procedure, and lists topics for review. We are trying to improve the quality of our online textbook as much as possible. Finally, we have added an Affiliates page and button. All purchases made by clicking on the links from the Affiliates page help our website financially, without costing you anything.

15 November 2007: We are adding to the new Consumer Goods section on the Buyer’s Guide. This lists many companies with whom we have an affiliate relationship. These companies pay us a percentage of all sales from our website, so we encourage you to visit their websites. We have decided to discontinue links to websites that require plug-ins. Unfortunately, many computers cannot download plug-ins, and we would like our website to be usable from any computer, with any browser. We are now updating the Breast chapter, and will split it into two sections - nonmalignant (normal, benign, atypia) and malignant (DCIS, malignancies, miscellaneous, males, children). We have decided to update the chapters more frequently that are visited the most, namely breast, soft tissue, ovary, kidney tumor, uterus, stains, thyroid, skin tumor, CNS tumor, skin nontumor, CD markers and bladder. We plan to update all chapters regularly, but will focus on these a little more. We are also spending more time writing, so we can update more quickly.

1 November 2007: We have extensively updated the Conjunctiva section of the Eye chapter with more text, references and images from the AFIP Fascicle third series. We have also switched to a faster server. Thanks to all who stopped by our booths at the CAP, ASCP, Wayne State University and Beaumont Conferences. Visit our Buyer’s Guide to check out the new Consumer Goods section, which features items of interest to the pathology community. We are also updating our New Products and Services page more frequently.

19 September 2007: (1) We have updated CD Markers CD240 to CD249 with extensive text, references and diagrams / images. These markers include CD240 (the RH CE and RH D antigens) and CD241 (RH AG), important for transfusion medicine; CD 243 (MDR-1), which has prognostic value in various malignancies; and CD246 (ALK1), which has diagnostic importance for anaplastic large cell lymphoma and inflammatory myofibroblastic tumor. (2) Every month, we check our 30,000+ image and reference links to minimize the number of broken links that you encounter. We have fixed almost all the broken links to GU images at WebPathology, and long term, have decided to put more images on our own server, including non-copyrighted AFIP images and donated images. (3) Over the next 4 weeks, we will be attending 4 conferences - Beaumont DNA Conference in Troy, Michigan, CAP in Chicago, ASCP in New Orleans and Wayne State University’s annual conference in Dearborn, Michigan. If you are attending any of these conferences, please stop by our booth and give us your feedback on what you like about the website and what we can do to make it more useful to you.

5 September 2007: (1) We posted a new article on our Management page, “Costly Coding and Documentation Errors”, by Chappy Manning, RN, CPC, Pathology Service Associates, LLC. The Management page contains articles written or adapted exclusively for PathologyOutlines.com relating to Billing (auditing, billing-general, compliance, direct billing and managed care) and Marketing of Pathology practices, as well as other practice related information. (2) Our Esophagus chapter was thoroughly reviewed and edited by Dr. Poonam Sharma, Creighton University Medical Center, Nebraska. (3) Our Laboratory-Other jobs page has a 2 for 1 special for postings through 31 October 2007. Please check this page for more details.

4 September 2007: We have added a new chapter on Transfusion Medicine, featuring Transfusion reactions, transfusion side effects and transfusion transmitted disease.

17 August 2007: We have updated the CD Markers Chapter for CD100 to CD110 with new text and references. We have updated the Top Book Sales page and have a new Monthly Website News (click here). We are currently writing new chapters on Transfusion Medicine and Employment Contracts, and are updating the Eye chapter.

1 August 2007: We added a Clinical Chemistry chapter, which initially contains thyroid function tests. We will add new classes of tests over time. We will be attending more conferences in the future to get more feedback from pathologists and lab personnel on what website features would be most helpful to you. Stop by our booths at CAP, ASCP and USCAP, as well as other smaller conferences, or email us with your suggestions at NatPernick@Hotmail.com.

15 July 2007: Congratulations to Drury (Drew) Hill and Loretta Pasillas, both from California, for winning $50 each from our drawing of those who signed up for our laboratory (non-pathologist) email list.

1 July 2007: We have extensively updated our Esophagus chapter, now with 116 topics, over 600 image links and over 600 references. We are pleased to include links to the beautiful images from the Frank Netter collection, and the non-copyrighted images from the AFIP Fascicle third series. We have expanded the entries in our Buyer's Guide and New Product and Services announcements. Check them out when deciding on laboratory purchases, or to stay up to date.

21 May 2007: We added a chapter on Heart-Tumor, which lists over 50 entities with over 400 images and 250 references. The images include high quality photomicrographs from the AFIP fascicle on Heart Tumors (those that are not copyrighted). We have updated the items available from our Amazon.com “store” (click on the link in the upper right hand corner of the Home Page). We have added a link for booking hotels to the conference page - if you use it, please give us some feedback, good or bad. See our Contests page for a new drawing for non-Pathologist personnel who sign up for our Laboratory Jobs email list. Finally, we sent out a new Monthly Website news email (click here to view it).

8 May 2007: (1) If you are a pathology assistant, cytotechnologist, medical technologist, histotechnologist or have a similar Laboratory but not Pathologist position, sign up for our Laboratory Jobs email list (email NatPernick@Hotmail.com - "subscribe to Laboratory jobs email list"), and automatically enter our drawing for $50 cash (drawing deadline is 30 June 2007). Every 2-3 weeks, we will also send you a free email of new Laboratory (but not pathologist) jobs posted at our website. (2) We have finished an extensive update of Cytokeratins in our Stains chapter, including CK1 to CK24, broad spectrum and high/low molecular weight keratins. This section includes uses of each stain, images and references. (3) To find a term on any page of our website, click Ctrl F (for "find") and type in the term.

20 April 2007: We added a new article on "Pricing for Pathology billing" to the Management Page (under Clinical Pathology Outlines). We have now organized the Cases of the Week by category, based on a visitor's suggestion (the link is on the Case of the Week page). The New Products page has several new entries.

4 April 2007: We updated the Soft Tissue chapter sections on lipomatous tumors based on your suggestions. Besides adding more content from textbooks and journals, and more image links, we added links to related images from the AFIP Fascicle, as well as information from the WHO, and we added more subcategories for the text. We have a new format for the table of contents for these tumors - let us know if you like it. Many of the image links to the Journal of Clinical Pathology no longer work, as this journal now requires registration. We are in the process of removing them.

20 March 2007. We have extensively updated the Soft Tissue chapter - Adipose tissue / liposarcoma sections, with additional text, image links and references. Enter our new contest with your tips on how PathologyOutlines.com is useful to you. The two best tips, in our judgment, will win $50 Amazon.com gift cards. Stop by booth #517 and visit us at USCAP in San Diego.

6 March 2007: We redesigned the Home Page to improve access speeds. Contact us if you are having any problems. We have two new Email lists - to receive a list of new books and to receive our new newsletter. Click on the Email updates button (left side of Home Page) for more information. We have updated the Top Book Sales for 2006 in our Books section. Please support our renewing advertisers Modern Pathology and Laboratory Investigation (ads on Home Page).

14 February 2007: We have added two original articles to the Management Page. "Pricing for Pathology Practices", by Mick Raich of Vachette Pathology, discusses important factors in your contract with your billing company. "The Case for Compliance: Why You Need an Effective Compliance Program", by John R. Outlaw of PSA, discusses the background of compliance programs, and why they are important. We have added a new chapter - Bone Marrow-nonneoplastic. This extensive chapter (1.5 MB in Word), has over 500 images and almost 400 references. It contains detailed discussions of normal bone marrow with micro descriptions and images (helpful when doing differentials), as well as information on benign changes (such as gelatinous transformation), infectious disorders (Candida, CMV, Parvovirus and others), systemic disorders (Fabry's disease, Gaucher's disease and others) and other topics. It also has numerous high quality images from the AFIP third series on bone marrow. Use it to find information fast on bone marrow topics for sign out, preparing talks, obtaining images or satisfying your curiosity.

29 January 2007: We have fixed the links on the Cervix page. We are now adding non-copyrighted links to the beautiful images from the AFIP Fascicles, third series, including those related to cervical pathology. We welcome several new corporate advertisers, including Voicebrook (speech recognition software), Centerchem (coagulation products) and Milestone Medical (microwave accelerated tissue processing). We also thank our renewing corporate advertisers of Vision Biosystems (reagents and tissue processors) and IMPAC (anatomic pathology computer systems).

2 January 2007: Best wishes for a happy New Year! Thanks to those who purchased some of the 700+ books sold through our website and Amazon.com or LWW.com in 2006. We have extensively updated CD Markers CD50 to CD99, and plan on updating chapters at a faster pace in 2007.

13 December 2006: We have updated the Ear chapter. There is a new Email update available (click on the button on the left side of our Home page). The Breast chapter is now available on PDA by clicking http://www.surgicalpathologyatlas.com/glfusion/filemgmt/index.php?id=3

1 December 2006: Our Books page, under Discounts, now lists a large number of books available from Amazon.com with discounts of 10% or more.

1 November 2006: We have extensively updated the Colon tumor chapter. We need gross and microscopic images for these colorectal carcinomas: post-treatment changes, intramucosal carcinoma, adenosquamous, glassy cell, hepatoid, metastases to colon, neuroendocrine and squamous cell.

10 October 2006: We upgraded our website server last weekend, which should speed up access to all of our pages. We apologize for any temporary problems.

11 September 2006: We have split the Colon chapter into nontumor and tumor, and updated the Colon-nontumor chapter. It now has 33 pages of text, over 600 image links and 500 references. The colon-tumor chapter will be updated next.

30 August 2006: We are changing our name from PathologyOutlines.com, LLC to PathologyOutlines.com, Inc., for tax reasons. You should not notice any other changes.

25 August 2006: We now have a PDA version of some chapters of the website. To obtain this version, offered for no charge, please visit http://www.surgicalpathologyatlas.com/glfusion/filemgmt/index.php?id=4 and follow the instructions.

21 August 2006: We have started to update our Stains chapter, beginning with the most popular stains. This will take several months, as our first topic, PAS, required 10 hours of work. We appreciate any feedback on the format for PAS, so we can use your suggestions when we update other stains. Also, don't forget that we have several search features for our website, including the Google box at the bottom of this page. They are outlined in the FAQs (link at the top of this page).

16 August 2006: Our Contests page has a short survey to improve the website, with a drawing for a $50 cash prize. We have added categories of Board Review and Statistics to the Books pages, as well as numerous new books. We are starting to incorporate our Cases of the Week into our Chapters. There is a special promotional rate for Pathology related job postings through October 31, 2006 (see this page).

24 July 2006: We added a new article to the Management Page - A Case Study in Increasing Practice Revenue through Managed Care Negotiations, by Mick Raich. Our Books page, now with 850 pathology books, now includes discounts available through the Barnes & Noble website (click on the Discounts link on the Books page). We have completed the July06 monthly link check of our website and corrected the bad links.

21 July 2006: Our website host recommends that users clear out their temporary Internet files from time to time to improve website performance. In Internet Explorer, click on Tools, then Internet Options, then Delete Files.

14 July 2006: We finished the new chapter on Lymph node - not lymphoma, which has over 40 pages of text, 500 references and 500 image links regarding normal lymph node histology, inclusions and infectious, inflammatory and neoplastic conditions (other than lymphoma). Let us know if you are interested in reviewing the CD Markers chapters, CD 1-49, CD 50-99 or CD 100-247.

5 July 2006: We have updated the list of top selling books from our Books pages (click on the Books button on the left hand side of the Home Page, then Top book sales in the table of contents) We continue to add new books to these pages, including 24 in May06 and 22 in June06. We have also posted a new Email Update summarizing changes made to the website in the past month, and Instructions for Reviewers on the Reviewers page.

5 June 2006: Our Management page has a new article by PSA, "Considerations for Outsourcing Billing Operations". We have also added many new conferences to our Conferences page, and posted a new "Email update", which describes recent changes to our website.

24 May 2006: We have extensively updated the chapter for CD Markers CD1 to CD49, which now has 32 pages of text, 480 images and 930 references. This update took over 100 hours, so we are spreading out the updates for the remaining CD markers. Check out the new listings for our Pathology related / Laboratory jobs, and contact us to advertise your open positions.

15 May 2006: In response to requests, we have compiled a list of suggestions on how you can support PathologyOutlines.com and make it a more helpful resource for yourself and our fellow pathologists. Click here for the suggestions.

8 May 2006: We added a new Management page article "Critical Strategies for Negotiating Contracts". Don't forget to purchase your Lippincott texts at www.LWW.com, using promotion code W5ECA1ZZ to save 10%, and to buy books and other products at Amazon.com through our Books page. These purchases help support our website without costing you anything.

28 April 2006: We are pleased to announce that Lippincott Williams & Wilkins (LWW) now offers visitors to PathologyOutlines.com a 10% discount on all products purchased at www.LWW.com, except for web-based products. Just use promotion code W5ECA1ZZ. Any purchases made through Lippincott with this code or through Amazon.com after visiting our Books page help our website financially, at no additional charge to you.

9 March 2006: We have a new Management page article on Managed Care Payment Shopping. We have begun to offer a simple conference posting for only $100, so everyone can afford to post all of their conferences on our popular conference page. Our highlighted conference listings with more text and images continue to cost only $400.

20 March 2006: We have separated jobs into a Pathologist Jobs page and a Pathology-related Jobs page. We have now completed the new Cervix-Cytology chapter, which has extensive cytology text and references and over 500 cytology image links. Check our new "images needed" section in this chapter to see if you have images that we need.

13 March 2006: We have completed the Cervix chapter, which has over 500 image links and 500 references. This chapter incorporates our new format changes to be made in all of our chapters as they are updated. We will include more images and references, the WHO classification, more information on grossing and features to report, more cytology images (for cervix, they are in a separate Cervix-cytology chapter), and an emphasis on journals with free text, which are highlighted in dark green. In addition, we are listing "images needed" for those who would like to donate digital images to help the large number of pathologists throughout the world who use our website.

20 February 2006: Thanks to all who visited our booth at USCAP. We are incorporating your suggestions, including a separate colored link (dark green) for journals with free full text. We are investigating putting the text of the outlines on a PDA. We are now link checking all chapters and other pages monthly, and fixing the bad links (a very time consuming task). If you want to use your collection of images from unusual cases to help pathologists throughout the world, please contact Dr. Pernick at NatPernick@Hotmail.com. Many pathologists cannot afford expensive textbooks and journals, but they have Internet access and can use our free website.

6 January 2006: Our Coagulation chapter has now been reviewed by Dr. Kendall Crookston, University of New Mexico Health Sciences Center, and his comments have been incorporated. By request, we are now also posting pathology-related nonpathologist jobs on our Jobs page.

23 December 2005: We have (finally) completed our CNS-tumor chapter, with 45 pages of text, 736 image links and 600 references. We wish all of our visitors a

healthy and happy New Year.

13 December 2005: Congratulations to Dr. Alan Schned of Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, winner of Cagle: Color Atlas and Text of Pulmonary Pathology, in our free book contest. We plan to announce the winner of the second book (Farhi: Pathology of Bone Marrow and Blood Cells) soon. This contest was open to subscribers to our email lists as of October 2005. Thanks to Lippincott Williams & Wilkins for donating these books.

18 November 2005: We have moved servers this week, a major maintenance task. Fortunately, the problems seemed to be limited to some returned emails yesterday (please resend) and pages that were temporarily unavailable. The new server should provide more reliable service and statistics.

19 October 2005: The winner of the Books page survey contest/drawing is Dr. Puja Puri of Arlington, Virginia (USA). We thank everyone who completed the Book survey, which provided useful feedback to improve the Books pages. We will announce the winner of the email contest/drawing for Lippincott books soon.

2 October 2005: Our Jobs page is now posting Part Time/Locums Positions, Open Residency Positions and Seeking Employment ads. Try our new Google search feature (below) to search our website. Click here to view a petition to save the AFIP. Thanks to all who completed our Books page survey.

7 September 2005: Please visit the new Contests page to learn about our drawings for two new pathology books - Farhi: Pathology of Bone Marrow and Blood Cells and Cagle: Color Atlas and Text of Pulmonary Pathology, courtesy of Lippincott Williams & Wilkins and $50 cash. We have updated the Breast chapter extensively, now with almost 1200 image links (including cytology), 600 references and 100 virtual slides. Visit us at CAP '05 (Booth #55) in Chicago, September 11-13, 2005.

2 August 2005: The Human Pathology links may not work, as the journal has apparently changed them. This seems to happen every 1-2 years for each journal. We check and correct all links when we update each chapter, but this means there are periods when links may not work. To solve this problem, we are including as many links as possible from non-journals (which may be more stable), and links to images stored on our server (which won't go bad). We apologize for any inconvenience.

25 July 2005: We have added an extensive chapter on Coagulation. We have also put the links for all chapters (AP, CP and Management) into one list in alphabetical order, and made the link for the New Products page into a button on the left hand side.

22 June 2005: We have extensively updated the Bone and Joints Chapters and split off Joints to be a separate chapter.

23 May 2005: We have finished the Skin-nontumor chapter. The Kidney-tumor chapter has now been reviewed and revised by Christiane Rakozy, M.D. We have added a topic to the Management page (under the Surgical Pathology topics). Our Books page is updated weekly, and now has over 700 titles, many with book reviews. If you want to add your own book review, please email us.

25 April 2005: We have extensively updated the Bladder chapter. We will be adding new Books and Reviews at least weekly to the Books page. We have added IMPAC's survey to our Computer-AP page, and added a new article from PSA to the Management page, which will be updated at least monthly with new articles. The About Us link (at the bottom) has also been revised.

8 April 2005: We have updated the Appendix chapter. We now have over 640 titles on our Books page, which is updated at least weekly, and are adding links to book reviews. We have a new Case of the Week (click on the button on the left hand side). Please email us with suggested topics to add to our Management page.

30 March 2005: We have added a Computer Systems-Anatomic Pathology page, under Pathology Practice Pages (in the center of our Home page). Our Books page now has over 600 titles. We have updated the Anus and perianal area chapter, and added a new article to the Management Page. We are pleased with the positive feedback we received from the USCAP conference, and welcome your comments about improving the website.

8 March 2005: We are expanding our Books page to make it as complete as possible (now with 165 books) and to link to book reviews. We have added a New Products/Services page, featuring announcements of interest to pathologists. We are updating our Outlines in alphabetical order, and have completed Adrenal Gland and Ampulla, with a plan to update each chapter every 12 months.

11 January 2005: We have completed the Eye chapter, and now have over 1300 pages of text and 10,000 links to images. We have also added a new article to the Management Page.

End of Website News