Breast malignant
Carcinoma subtypes
Lobular carcinoma - trabecular variant


Topic Completed: 1 August 2012

Minor changes: 25 June 2020

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Trabecular variant of lobular carcinoma

Monika Roychowdhury, M.D.
Page views in 2020 to date: 10
Cite this page: Roychowdhury M. OLD trabecular. PathologyOutlines.com website. http://www.pathologyoutlines.com/oldtopics/breastmalignantlobulartrabecular.html. Accessed August 7th, 2020.
Definition / general
  • Classic lobular carcinoma infiltrating in trabeculae (linear bands) two to four cells thick
  • Trabecula - supporting beam of bar, plural is trabeculae
  • Trabeculae variant is usually not considered a distinct variant because it overlaps the classic and mixed patterns (Schnitt: Biopsy Interpretation of the Breast, 2nd Edition, 2009)
Electron microscopy description
  • Tumor cells are similar to classic lobular carcinoma (J Pathol 1985;145:39)
  • Compared to LCIS, tumor cells are more irregular, with more organelles and filaments
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