Thyroid gland
Other carcinoma
OLD Anaplastic carcinoma - rhabdoid variant


Topic Completed: 1 March 2009

Revised: 13 September 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: anaplastic carcinoma rhabdoid thyroid

Related Topic: Anaplastic carcinoma

Shahid Islam, M.D., Ph.D.
Page views in 2019 to date: 1
Cite this page: Islam, S. OLD Anaplastic carcinoma - rhabdoid variant. PathologyOutlines.com website. http://www.pathologyoutlines.com/oldtopics/thyroidUndiffrhabdoid.html. Accessed October 20th, 2019.
Definition / general
  • Very rare
  • Aggressive, often metastasizes
  • To date, always rapidly fatal
Epidemiology
  • Usually women, mean 56 years, range 42 - 67 years
Case reports
Microscopic (histologic) description
  • Highly cellular, solid infiltrative growth with extracapsular invasion
  • Tumor cells are large and pleomorphic with abundant cytoplasm, eosinophilic inclusions, eccentric nuclei with distinct nucleoli
Microscopic (histologic) images

Images hosted on other servers:

Various images

Cytology, gross, H&E

Positive stains
Negative stains
Electron microscopy description
  • Whorled cytoplasmic filaments
Molecular / cytogenetics description
  • RET-PTC3 gene rearrangement
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