Table of contents
Primary references
top
AJCC Cancer Staging Manual (7th ed)
Weiss: Soft Tissue Tumors (5th edition, 2007)
Fletcher:Pathology and Genetics of Tumours of Soft Tissue and Bone (AFIP 3rd Series, Vol 30), 2004
Fletcher:Pathology and Genetics of Tumours of Soft Tissue and Bone (WHO, Vol 5), 2002, PDF
Websites with images: PathoPic USCAP (virtual slides) WebPathology.com
General:
primary references
approach to diagnosis
architectural patterns
cell types
grading
molecular
normal
sarcomas-general
staging
syndromes
Infections, inflammation and hematoma: general granulomatous hematoma necrotizing fasciitis PVP granuloma tumoral calcinosis
Tumors
Adipose tissue: embryology & physiology white fat brown fat
lipoma and variants: lipoma angiolipoma chondroid fibrolipoma intramuscular lipoma arborescens lipoma of tendon sheath lipomatosis lipomatosis of nerve lumbosacral myolipoma myxoid nevus lipomatosus pelvic pleomorphic / spindle cell
other benign lesions: hemosiderotic fibrohistiocytic hibernoma lipoblastoma subconjunctival herniated orbital fat
liposarcoma: general atypical lipomatous tumor / well differentiated (variants: inflammatory lipoleiomyosarcoma dedifferentiated) myxoid-general (variants: myxoid-well differentiated myxoid-round cell) pleomorphic mixed type sclerosing poorly differentiated
Extraskeletal bone tumors: aneurysmal bone cyst chondroma chondrosarcoma chordoma Ewing/PNET osteosarcoma parachordoma
Fibroblastic / myofibroblastic: general fibroblastic/myofibroblastic - normal angiofibroma angiomyofibroblastoma calcifying aponeurotic fibroma calcifying fibrous tumor cellular angiofibroma dermatofibrosarcoma protuberant (dfsp) (variants: myxoid variant of dfsp sarcomas arising in dfsp) desmoplastic fibroblastoma elastofibroma eosinophilic fasciitis fibroma of tendon sheath fibromatosis-general fibromatosis-superficial fibromatosis-deep fibromatosis colli fibrosarcoma-adult fibrosarcoma-infantile fibrous hamartoma of infancy focal myositis Gardner fibroma giant cell angiofibroma giant cell fibroblastoma hemangiopericytoma inclusion body fibromatosis inflammatory myofibroblastic tumor intranodal palisaded myofibroblastoma ischemic fasciitis juvenile hyaline fibromatosis lipofibromatosis low grade fibromyxoid sarcoma low grade myofibroblastic sarcoma mammary type myofibroblastoma myofibroma / myofibromatosis myositis ossificans myxofibrosarcoma myxoinflammatory fibroblastic sarcoma nodular fasciitis and related lesions nuchal fibrocartilaginous pseudotumor nuchal type fibroma ossifying fibromyxoid tumor pleomorphic fibroma proliferative fasciitis proliferative myositis proliferative peribursitis sclerosing epithelioid fibrosarcoma solitary fibrous tumor superficial acral fibromyxoma
Fibrohistiocytic: benign fibrous histiocytoma and variants: superficial deep aneurysmal angiomatoid atypical cellular epithelioid juvenile xanthogranuloma
other benign lesions: general atypical fibroxanthoma giant cell tumor of soft tissue giant cell tumor of tendon sheath-diffuse giant cell tumor of tendon sheath-localized PHAT plexiform fibrohistiocytic tumor
malignant: MFH-giant cell MFH-inflammatory MFH-pleomorphic
Mesenchymal: hamartoma mesenchymoma phosphaturic mesenchymal tumor
Peripheral nerve:
neurofibroma: general pacinian pigmented plexiform neurofibromatosis type 1 type 2
other benign: normal myxopapillary ependymoma nerve sheath myxoma neuroma neurothekeoma perineurioma pigmented neuroectodermal tumor of infancy schwannoma
malignant: lymphoma MPNST
Perivascular epithelioid cell: PEComa-general abdominopelvic sarcoma falciform ligament / ligamentum teres
Skeletal Muscle: skeletal muscle-normal neuromuscular hamartoma myxoma
rhabdomyoma: adult fetal genital
rhabdomyosarcoma: general alveolar anaplastic embryonal pleomorphic sclerosing
Smooth Muscle: general angioleiomyoma EBV-related
leiomyoma: classic bizarre cutaneous epithelioid genital deep soft tissue
leiomyosarcoma: general cutaneous epithelioid myxoid pleomorphic rhabdoid features
Vascular:
normal/benign: normal bacillary angiomatosis glomus hemangioma and variants -anastomosing -microvenular -symplastic intravascular papillary endothelial hyperplasia myopericytoma vascular ectasias venous hemangioma
low/intermediate grade: giant cell angioblastoma hemangioendothelioma Kaposi sarcoma
high grade: angiosarcoma intimal sarcoma
Lymphangioma: -general -cystic -post-radiation lymphangiomatosis lymphangioendothelioma lymphangiomyoma lymphangiosarcoma
Other: alveolar soft part sarcoma clear cell sarcoma desmoplastic small round cell tumor epithelioid sarcoma granular cell tumor metastases myoepithelial carcinoma myospherulosis myxoma rhabdoid tumor sinus histiocytosis with massive lymphadenopathy synovial sarcoma teratoma
Superpage
Index (Alphabetical Table of Contents)
A-E: adipose: embryology & physiology alveolar soft part sarcoma anastomosing hemangioma aneurysmal BFH angiofibroma angioleiomyoma angiolipoma angiomatoid BFH angiomyofibroblastoma angiosarcoma approach to diagnosis architectural patterns atypical BFH atypical fibroxanthoma atypical lipomatous tumor / well differentiated bacillary angiomatosis benign fibrous histiocytoma (superficial) brown fat calcifying aponeurotic fibroma calcifying fibrous tumor cell types cellular angiofibroma cellular BFH chondroid lipoma clear cell sarcoma dedifferentiated liposarcoma deep benign fibrous histiocytoma dermatofibrosarcoma protuberans desmoplastic fibroblastoma desmoplastic small round cell tumor EBV-related smooth muscle elastofibroma eosinophilic fasciitis epithelioid BFH epithelioid sarcoma extraskeletal aneurysmal bone cyst extraskeletal chondroma extraskeletal chondrosarcoma extraskeletal chordoma extraskeletal Ewing/PNET extraskeletal osteosarcoma
F-J: fibroblastic/myofibroblastic - general fibroblastic/myofibroblastic - normal fibrohistiocytic-general fibrolipoma fibroma of tendon sheath fibromatosis colli fibromatosis-deep fibromatosis-general fibromatosis-superficial fibrosarcoma-adult fibrosarcoma-infantile fibrous hamartoma of infancy focal myositis Gardner fibroma giant cell angioblastoma giant cell angiofibroma giant cell fibroblastoma giant cell tumor of soft tissue giant cell tumor of tendon sheath-diffuse giant cell tumor of tendon sheath-localized glomus grading granular cell tumor granulomatous hemangioendothelioma hemangioma and variants hemangiopericytoma hematoma hemosiderotic fibrohistiocytic lipomatous lesion hibernoma inclusion body fibromatosis infections-general inflammatory liposarcoma inflammatory myofibroblastic tumor intimal sarcoma intramuscular lipoma intranodal palisaded myofibroblastoma intravascular papillary endothelial hyperplasia ischemic fasciitis juvenile hyaline fibromatosis juvenile xanthogranuloma
K-O: Kaposi sarcoma leiomyoma-bizarre leiomyoma-classic leiomyoma-cutaneous leiomyoma-deep soft tissue leiomyoma-epithelioid leiomyoma-genital leiomyosarcoma-cutaneous leiomyosarcoma-epithelioid leiomyosarcoma-general leiomyosarcoma-myxoid leiomyosarcoma-pleomorphic leiomyosarcoma-rhabdoid features lipoblastoma lipofibromatosis lipoleiomyosarcoma lipoma lipoma arborescens lipoma of tendon sheath lipomatosis lipomatosis of nerve liposarcoma-general low grade fibromyxoid sarcoma low grade myofibroblastic sarcoma lumbosacral lipoma lymphangioma-general lymphangioma-cystic lymphangioma-post-radiation lymphangiomatosis lymphangioendothelioma lymphangiomyoma lymphangiosarcoma lymphoma mammary type myofibroblastoma mesenchymal hamartoma mesenchymoma metastases MFH-giant cell MFH-inflammatory MFH-pleomorphic microvenular hemangioma mixed type liposarcoma molecular MPNST myoepithelial carcinoma myofibroma / myofibromatosis myolipoma myopericytoma myositis ossificans myospherulosis myxofibrosarcoma myxoid lipoma myxoid liposarcoma-general myxoid-round cell liposarcoma myxoid-well differentiated liposarcoma myxoinflammatory fibroblastic sarcoma myxoma myxopapillary ependymoma necrotizing fasciitis nerves-normal nerve sheath myxoma neurofibroma-general neurofibroma-pacinian neurofibroma-pigmented neurofibroma-plexiform neurofibromatosis type 1 neurofibromatosis type 2 neuroma neuromuscular hamartoma neurothekeoma nevus lipomatosus nodular fasciitis and related lesions nuchal fibrocartilaginous pseudotumor nuchal type fibroma ossifying fibromyxoid tumor
P-Z: parachordoma PEComa PEComa-abdominopelvic sarcoma PEComa-falciform ligament / ligamentum teres pelvic lipoma perineurioma phosphaturic mesenchymal tumor pigmented neuroectodermal tumor of infancy pleomorphic fibroma pleomorphic hyalinizing angiectatic tumor pleomorphic liposarcoma pleomorphic / spindle cell lipoma plexiform fibrohistiocytic tumor primary references proliferative fasciitis proliferative myositis proliferative peribursitis PVP granuloma rhabdoid tumor rhabdomyoma-adult rhabdomyoma-fetal rhabdomyoma-genital rhabdomyosarcoma-alveolar rhabdomyosarcoma-anaplastic rhabdomyosarcoma-embryonal rhabdomyosarcoma-general rhabdomyosarcoma-pleomorphic rhabdomyosarcoma-sclerosing sarcomas-general schwannoma sclerosing epithelioid fibrosarcoma sclerosing poorly differentiated liposarcoma sinus histiocytosis with massive lymphadenopathy skeletal muscle-normal smooth muscle general soft tissue-normal solitary fibrous tumor subconjunctival herniated orbital fat staging superficial acral fibromyxoma symplastic hemangioma syndromes synovial sarcoma teratoma tumoral calcinosis vascular ectasias vasculature-normal venous hemangioma white fat
Infections, inflammation and hematoma: general granulomatous hematoma necrotizing fasciitis PVP granuloma tumoral calcinosis
Tumors
Adipose tissue: embryology & physiology white fat brown fat
lipoma and variants: lipoma angiolipoma chondroid fibrolipoma intramuscular lipoma arborescens lipoma of tendon sheath lipomatosis lipomatosis of nerve lumbosacral myolipoma myxoid nevus lipomatosus pelvic pleomorphic / spindle cell
other benign lesions: hemosiderotic fibrohistiocytic hibernoma lipoblastoma subconjunctival herniated orbital fat
liposarcoma: general atypical lipomatous tumor / well differentiated (variants: inflammatory lipoleiomyosarcoma dedifferentiated) myxoid-general (variants: myxoid-well differentiated myxoid-round cell) pleomorphic mixed type sclerosing poorly differentiated
Extraskeletal bone tumors: aneurysmal bone cyst chondroma chondrosarcoma chordoma Ewing/PNET osteosarcoma parachordoma
Fibroblastic / myofibroblastic: general fibroblastic/myofibroblastic - normal angiofibroma angiomyofibroblastoma calcifying aponeurotic fibroma calcifying fibrous tumor cellular angiofibroma dermatofibrosarcoma protuberant (dfsp) (variants: myxoid variant of dfsp sarcomas arising in dfsp) desmoplastic fibroblastoma elastofibroma eosinophilic fasciitis fibroma of tendon sheath fibromatosis-general fibromatosis-superficial fibromatosis-deep fibromatosis colli fibrosarcoma-adult fibrosarcoma-infantile fibrous hamartoma of infancy focal myositis Gardner fibroma giant cell angiofibroma giant cell fibroblastoma hemangiopericytoma inclusion body fibromatosis inflammatory myofibroblastic tumor intranodal palisaded myofibroblastoma ischemic fasciitis juvenile hyaline fibromatosis lipofibromatosis low grade fibromyxoid sarcoma low grade myofibroblastic sarcoma mammary type myofibroblastoma myofibroma / myofibromatosis myositis ossificans myxofibrosarcoma myxoinflammatory fibroblastic sarcoma nodular fasciitis and related lesions nuchal fibrocartilaginous pseudotumor nuchal type fibroma ossifying fibromyxoid tumor pleomorphic fibroma proliferative fasciitis proliferative myositis proliferative peribursitis sclerosing epithelioid fibrosarcoma solitary fibrous tumor superficial acral fibromyxoma
Fibrohistiocytic: benign fibrous histiocytoma and variants: superficial deep aneurysmal angiomatoid atypical cellular epithelioid juvenile xanthogranuloma
other benign lesions: general atypical fibroxanthoma giant cell tumor of soft tissue giant cell tumor of tendon sheath-diffuse giant cell tumor of tendon sheath-localized PHAT plexiform fibrohistiocytic tumor
malignant: MFH-giant cell MFH-inflammatory MFH-pleomorphic
Mesenchymal: hamartoma mesenchymoma phosphaturic mesenchymal tumor
Peripheral nerve:
neurofibroma: general pacinian pigmented plexiform neurofibromatosis type 1 type 2
other benign: normal myxopapillary ependymoma nerve sheath myxoma neuroma neurothekeoma perineurioma pigmented neuroectodermal tumor of infancy schwannoma
malignant: lymphoma MPNST
Perivascular epithelioid cell: PEComa-general abdominopelvic sarcoma falciform ligament / ligamentum teres
Skeletal Muscle: skeletal muscle-normal neuromuscular hamartoma myxoma
rhabdomyoma: adult fetal genital
rhabdomyosarcoma: general alveolar anaplastic embryonal pleomorphic sclerosing
Smooth Muscle: general angioleiomyoma EBV-related
leiomyoma: classic bizarre cutaneous epithelioid genital deep soft tissue
leiomyosarcoma: general cutaneous epithelioid myxoid pleomorphic rhabdoid features
Vascular:
normal/benign: normal bacillary angiomatosis glomus hemangioma and variants -anastomosing -microvenular -symplastic intravascular papillary endothelial hyperplasia myopericytoma vascular ectasias venous hemangioma
low/intermediate grade: giant cell angioblastoma hemangioendothelioma Kaposi sarcoma
high grade: angiosarcoma intimal sarcoma
Lymphangioma: -general -cystic -post-radiation lymphangiomatosis lymphangioendothelioma lymphangiomyoma lymphangiosarcoma
Other: alveolar soft part sarcoma clear cell sarcoma desmoplastic small round cell tumor epithelioid sarcoma granular cell tumor metastases myoepithelial carcinoma myospherulosis myxoma rhabdoid tumor sinus histiocytosis with massive lymphadenopathy synovial sarcoma teratoma
Superpage
Index (Alphabetical Table of Contents)
A-E: adipose: embryology & physiology alveolar soft part sarcoma anastomosing hemangioma aneurysmal BFH angiofibroma angioleiomyoma angiolipoma angiomatoid BFH angiomyofibroblastoma angiosarcoma approach to diagnosis architectural patterns atypical BFH atypical fibroxanthoma atypical lipomatous tumor / well differentiated bacillary angiomatosis benign fibrous histiocytoma (superficial) brown fat calcifying aponeurotic fibroma calcifying fibrous tumor cell types cellular angiofibroma cellular BFH chondroid lipoma clear cell sarcoma dedifferentiated liposarcoma deep benign fibrous histiocytoma dermatofibrosarcoma protuberans desmoplastic fibroblastoma desmoplastic small round cell tumor EBV-related smooth muscle elastofibroma eosinophilic fasciitis epithelioid BFH epithelioid sarcoma extraskeletal aneurysmal bone cyst extraskeletal chondroma extraskeletal chondrosarcoma extraskeletal chordoma extraskeletal Ewing/PNET extraskeletal osteosarcoma
F-J: fibroblastic/myofibroblastic - general fibroblastic/myofibroblastic - normal fibrohistiocytic-general fibrolipoma fibroma of tendon sheath fibromatosis colli fibromatosis-deep fibromatosis-general fibromatosis-superficial fibrosarcoma-adult fibrosarcoma-infantile fibrous hamartoma of infancy focal myositis Gardner fibroma giant cell angioblastoma giant cell angiofibroma giant cell fibroblastoma giant cell tumor of soft tissue giant cell tumor of tendon sheath-diffuse giant cell tumor of tendon sheath-localized glomus grading granular cell tumor granulomatous hemangioendothelioma hemangioma and variants hemangiopericytoma hematoma hemosiderotic fibrohistiocytic lipomatous lesion hibernoma inclusion body fibromatosis infections-general inflammatory liposarcoma inflammatory myofibroblastic tumor intimal sarcoma intramuscular lipoma intranodal palisaded myofibroblastoma intravascular papillary endothelial hyperplasia ischemic fasciitis juvenile hyaline fibromatosis juvenile xanthogranuloma
K-O: Kaposi sarcoma leiomyoma-bizarre leiomyoma-classic leiomyoma-cutaneous leiomyoma-deep soft tissue leiomyoma-epithelioid leiomyoma-genital leiomyosarcoma-cutaneous leiomyosarcoma-epithelioid leiomyosarcoma-general leiomyosarcoma-myxoid leiomyosarcoma-pleomorphic leiomyosarcoma-rhabdoid features lipoblastoma lipofibromatosis lipoleiomyosarcoma lipoma lipoma arborescens lipoma of tendon sheath lipomatosis lipomatosis of nerve liposarcoma-general low grade fibromyxoid sarcoma low grade myofibroblastic sarcoma lumbosacral lipoma lymphangioma-general lymphangioma-cystic lymphangioma-post-radiation lymphangiomatosis lymphangioendothelioma lymphangiomyoma lymphangiosarcoma lymphoma mammary type myofibroblastoma mesenchymal hamartoma mesenchymoma metastases MFH-giant cell MFH-inflammatory MFH-pleomorphic microvenular hemangioma mixed type liposarcoma molecular MPNST myoepithelial carcinoma myofibroma / myofibromatosis myolipoma myopericytoma myositis ossificans myospherulosis myxofibrosarcoma myxoid lipoma myxoid liposarcoma-general myxoid-round cell liposarcoma myxoid-well differentiated liposarcoma myxoinflammatory fibroblastic sarcoma myxoma myxopapillary ependymoma necrotizing fasciitis nerves-normal nerve sheath myxoma neurofibroma-general neurofibroma-pacinian neurofibroma-pigmented neurofibroma-plexiform neurofibromatosis type 1 neurofibromatosis type 2 neuroma neuromuscular hamartoma neurothekeoma nevus lipomatosus nodular fasciitis and related lesions nuchal fibrocartilaginous pseudotumor nuchal type fibroma ossifying fibromyxoid tumor
P-Z: parachordoma PEComa PEComa-abdominopelvic sarcoma PEComa-falciform ligament / ligamentum teres pelvic lipoma perineurioma phosphaturic mesenchymal tumor pigmented neuroectodermal tumor of infancy pleomorphic fibroma pleomorphic hyalinizing angiectatic tumor pleomorphic liposarcoma pleomorphic / spindle cell lipoma plexiform fibrohistiocytic tumor primary references proliferative fasciitis proliferative myositis proliferative peribursitis PVP granuloma rhabdoid tumor rhabdomyoma-adult rhabdomyoma-fetal rhabdomyoma-genital rhabdomyosarcoma-alveolar rhabdomyosarcoma-anaplastic rhabdomyosarcoma-embryonal rhabdomyosarcoma-general rhabdomyosarcoma-pleomorphic rhabdomyosarcoma-sclerosing sarcomas-general schwannoma sclerosing epithelioid fibrosarcoma sclerosing poorly differentiated liposarcoma sinus histiocytosis with massive lymphadenopathy skeletal muscle-normal smooth muscle general soft tissue-normal solitary fibrous tumor subconjunctival herniated orbital fat staging superficial acral fibromyxoma symplastic hemangioma syndromes synovial sarcoma teratoma tumoral calcinosis vascular ectasias vasculature-normal venous hemangioma white fat
Primary references
top
AJCC Cancer Staging Manual (7th ed)
Weiss: Soft Tissue Tumors (5th edition, 2007)
Fletcher:Pathology and Genetics of Tumours of Soft Tissue and Bone (AFIP 3rd Series, Vol 30), 2004
Fletcher:Pathology and Genetics of Tumours of Soft Tissue and Bone (WHO, Vol 5), 2002, PDF
Websites with images: PathoPic USCAP (virtual slides) WebPathology.com
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