Superpage - Images
Page views in 2024 to date: 14

Acute suppurative
Radiology images

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Osteomyelitis of mandible

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Absorption of cortical bone

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CT scan

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Various images

Microscopic (histologic) images

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H&E and GMS


Adenoid ameloblastoma
Radiology images

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Diffuse periapical radiolucency

Diffuse periapical radiolucency

Microscopic (histologic) images

Contributed by Elizabeth Ann Bilodeau, D.M.D., M.D., M.S.Ed.
Epithelial whorls

Epithelial whorls

Cribriform architecture and eosinophilic matrix

Cribriform architecture and eosinophilic matrix

Focal ghost cell keratinization

Focal ghost cell keratinization

Dentinoid deposits

Dentinoid deposits

Increased mitotic activity

Increased mitotic activity

Duct-like structures and ghost cell keratinization

Duct-like structures and ghost cell keratinization



Adenomatoid odontogenic tumor
Radiology images

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Radiolucency, engulfing tooth, extending beyond crown

Radiolucency, engulfing tooth, extending beyond crown

Microscopic (histologic) images

Contributed by Elizabeth Ann Bilodeau, D.M.D., M.D., M.S.Ed. and Kelly Magliocca, D.D.S., M.P.H. (Case #490)
Thick fibrous capsule

Thick fibrous capsule

Cribriform areas

Cribriform areas

Rosette-like structure

Rosette-like structure

Cellular area with focal matrix deposition

Cellular area with focal matrix deposition

Nodular appearance

Nodular appearance

Thick capsule

Thick capsule


Ameloblastic carcinoma
Radiology images

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Orthopantomogram

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Lucent lesion

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Axial non-contrast CT

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Axial MRI

Clinical images

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Extraoral swelling

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Pus discharge

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Intra-oral swelling

Gross images

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Resected specimen

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Ameloblastic carcinoma Ameloblastic carcinoma

Ameloblastic carcinoma



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Low power

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Higher power

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Cytological atypia

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Necrosis


Ameloblastic fibroma
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Ameloblastic fibroma

Ameloblastic fibroma

Odontogenic islands with cystic change, within immature mesenchymal stroma Odontogenic islands with cystic change, within immature mesenchymal stroma Odontogenic islands with cystic change, within immature mesenchymal stroma

Odontogenic islands with cystic change, within immature mesenchymal stroma


AF at scanning magnification

AF at scanning magnification

Odontogenic islands

Odontogenic islands

Odontogenic cords within immature mesenchymal stroma Odontogenic cords within immature mesenchymal stroma

Odontogenic cords within immature mesenchymal stroma


Ameloblastoma
Radiology images

Contributed by Ashley Aiken, M.D., Stephanie Drew, D.D.S. and Shelly Abramowicz, D.M.D., M.P.H.
Case 1: coronal CT view

Case 1: coronal CT view

Case 2: sagittal CT view

Case 2: sagittal CT view

Case 3: coronal CT view

Case 3: coronal CT view

Case 4: panorex radiograph

Case 4:
panorex radiograph

Case 5: panorex radiograph, unicystic type

Case 5:
panorex radiograph,
unicystic type

Clinical images

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Maxillary mass

Mandibular mass

Gross images

Contributed by Kelly Magliocca, D.D.S., M.P.H. and Andy Balicki, P.A.
Case 1: Mandibular granular cell ameloblastoma

Case 1: mandibular granular cell ameloblastoma

Case 2: Mandibular ameloblastoma

Case 2: mandibular ameloblastoma

Case 3: Mandibular ameloblastoma

Case 3: mandibular ameloblastoma

Case 5: Mandibular ameloblastoma, unicystic type

Case 5: mandibular ameloblastoma, unicystic type

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H. and Anne C. McLean-Holden, D.M.D., M.S.
Case 1: granular cell change Case 1: granular cell change

Case 1: granular cell change

Case 2: follicular growth

Case 2: follicular growth

Case 2: plexiform growth Case 2: plexiform growth

Case 2: plexiform growth

Case 3: follicular growth and cystic change

Case 3: follicular growth and cystic change


Case 3: follicular growth

Case 3: follicular growth

Case 4: follicular growth and cystic change

Case 4: follicular growth and cystic change

Case 4: cystic tumor change

Case 4: cystic tumor change

Case 4: follicular growth

Case 4: follicular growth

Case 4: cystic change

Case 4: cystic change

Case 5: unicystic type, decalcified

Case 5: unicystic type, decalcified


Case 5: unicystic type, nondecalcified Case 5: unicystic type, nondecalcified Case 5: unicystic type, nondecalcified

Case 5: unicystic type, nondecalcified

BRAF V600E

BRAF V600E

CK19

CK19

CK5

CK5

Cytology images

Contributed by Abdulwahab Ewaz, M.D.
Pap stain Pap stain

Pap stain

Diff-Quik Diff-Quik

Diff-Quik

Videos

Overview of odontogenic tumors by Dr. Khurram


Anatomy & histology
Microscopic (histologic) images

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Developing tooth (odontoblast and periodontal membrane)


Calcifying epithelial odontogenic tumor
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Calcifying epithelial odontogenic tumor

Calcifying epithelial odontogenic tumor


Calcifying odontogenic cyst
Radiology images

Contributed by Elizabeth Ann Bilodeau, D.M.D., M.D., M.S.Ed.

Coronal CT

Sagittal CT

Axial CT

Gross images

Contributed by Elizabeth Ann Bilodeau, D.M.D., M.D., M.S.Ed.

Opened and sectioned cyst

Microscopic (histologic) images

Contributed by Elizabeth Ann Bilodeau, D.M.D., M.D., M.S.Ed. and Keith D. Hunter, B.D.S., Ph.D.

Ameloblastomatous lining & ghost cells

Calcification of ghost cells

Island of epithelium with ghost cells

β catenin

LEF1


Cemento-osseous dysplasia
Radiology images

Contributed by Nadim M. Islam, D.D.S., B.D.S.
Classic radiolucent rim and central opacity

Classic radiolucent rim and central opacity

Multiquadrant mixed masses with expansion Multiquadrant mixed masses with expansion Multiquadrant mixed masses with expansion

Multiquadrant mixed masses with expansion

Focal lucent rim with central opacity Focal lucent rim with central opacity

Focal lucent rim with central opacity

Clinical images

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Excision

Gross images

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Tumor adjacent to tooth

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H. and Nadim M. Islam, D.D.S., B.D.S.
Cemento-osseous dysplasia

Cemento-osseous dysplasia

Cemental spherules and modestly cellular stroma

Cemental spherules and modestly cellular stroma

Spherules joining into ginger root-like formations

Spherules joining into ginger root-like formations

Lack of brush borders helps diagnosis


Cemento-ossifying fibroma / ossifying fibroma
Radiology images

Contributed by Molly Housley Smith, D.M.D., Thomas W. Fonner, D.M.D., Carlton Taylor, D.M.D., Firas Katabi, D.D.S. and Nish Shah, D.M.D., M.D.
Radiolucency in Anterior Mandible

Radiolucency in anterior mandible

Expansile lesion of mandible

Expansile lesion of mandible

Cortical destruction Cortical destruction

Cortical destruction

Root Divergence

Root divergence

Clinical images

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Large solitary swelling obliterating buccal vestibule

Large solitary swelling obliterating buccal vestibule

Bony mass in maxilla

Bony mass in maxilla

Intraoperative exposure of COF showing clear distinction between the lesion and healthy bone

Distinction between lesion and healthy bone

Gross images

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Excision

Excision

Microscopic (histologic) images

Contributed by Saira Javeed, M.B.B.S., M.Phil., Kelly Magliocca, D.D.S., M.P.H. and Molly Housley Smith, D.M.D.
Well circumscribed solid tumor mass

Well circumscribed solid tumor mass

Rounded to spherical variable sized cementum-like ossicles Rounded to spherical variable sized cementum-like ossicles

Rounded to spherical variable sized cementum-like ossicles

Benign fibro-osseous proliferation

Benign fibro-osseous proliferation


Rounded mineralized droplets

Rounded mineralized droplets

Fibro-osseous proliferation

Fibro-osseous proliferation

Woven Bone

Woven bone

Brush borders

Brush borders

Molecular / cytogenetics images

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MDM2 amplification by FISH

MDM2 amplification by FISH

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CDC73 mutations in sporadic tumors


Cementoblastoma
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Cementoblastoma

Cementoblastoma


Central giant cell granuloma
Radiology images

Contributed by Nasir Ud Din, M.B.B.S.
CGCG of mandible, premolar region (orthopantomogram)

CGCG of
mandible,
premolar region
(orthopantomogram)

Mandibular body CGCG (orthopantomogram)

Mandibular body
CGCG
(orthopantomogram)

Left mandibular CGCG

Left mandibular CGCG

CGCG of lower incisor region

CGCG of lower incisor region

Clinical images

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Right side submandibular swelling

Right side submandibular swelling

oval lesion involving left side mandible

Oval lesion involving left side mandible

Gross images

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Fleshy, reddish brown, hemorrhagic appearance

Fleshy, reddish brown, hemorrhagic appearance

Microscopic (histologic) images

Contributed by Nasir Ud Din, M.B.B.S.
Lobulated architecture

Lobulated architecture

Lobulation

Lobulation

Periphery of lobule

Periphery of lobule

Woven bone

Woven bone

Lobule center

Lobule center

Fibroblast and giant cells

Fibroblast and giant cells

Cytology images

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Giant cell with occasional spindle cells and hemorrhagic background

Giant cell with occasional
spindle cells and
hemorrhagic background

Videos

Central giant cell granuloma


Cherubism
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Cherubism

Cherubism


Chronic recurrent multifocal
Diagrams / tables

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Treatment of CNO/CRMO

Clinical images

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Expansion of left ramus

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"Bone-on-bone" pattern

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Swelling of left masseter muscle

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Uptake of radionucleotide

Microscopic (histologic) images

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Early and late stages of CRMO


Clear cell carcinoma of salivary gland
Clinical images

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Echo, CT, MRI

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Local findings

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Mass

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Operative findings

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Postoperative

Gross images

Contributed by Dr. Pooja Navale:

Case of the Month #483, cut section after fixation

Microscopic (histologic) images

Contributed by Dr. Pooja Navale:


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Stratified squamous epithelium

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Mitotic figures

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Islands of of epithelial cells

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Hyalinized areas

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Carmine stain


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PAS

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p63. CD10, PAS

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P63+

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Pancytokeratin+

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AE1/AE3, S100, SMA


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Mucicarmine-

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SMA-

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Calponin-

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S100-


Clear cell odontogenic carcinoma
Clinical images

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Buccal cortical expansion
with ulceration

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Intraoral ulcerated growth

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Bone destruction in
symphysis region

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Fig A: radiolucent lesion
in posterior segment

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Ill defined
radiolucent lesion

Gross images

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Composite resection

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Clear cell odontogenic carcinoma

Clear cell odontogenic carcinoma



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Various H&E

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Congo red stain

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Tumor cells

Molecular / cytogenetics images

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Interphase cells


Condensing osteitis
Radiology images

Contributed by Molly Housley Smith, D.M.D. and John Kalmar, D.M.D., Ph.D.
Apical to carious teeth

Apical to carious teeth

Residual opacity

Residual opacity

Panorex image, condensing osteitis

Panorex



Images hosted on other servers:
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Periapical

Microscopic (histologic) images

Contributed by Molly Housley Smith, D.M.D.
Scant fibrous stroma

Scant fibrous stroma

Nonspecific bone

Nonspecific bone

Remodeling bone

Remodeling bone

Prominent resting and reversal lines

Prominent resting and reversal lines


Dentigerous cyst
Radiology images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Cropped panorex

Cropped panorex



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Central variety

Central variety

Lateral variety

Lateral variety

Multiple radiopaque masses with thin radiolucent rim

Multiple radiopaque masses with thin radiolucent rim

Expansion and thinning of the bony sinus wall

Expansion and thinning of the bony sinus wall

Clinical images

Images hosted on other servers:
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Swelling of right maxilla and left mandibular region

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Swelling of right cheek

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Intraoral involvement of maxillary right quadrant

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Surgical exposure of lesional site

Gross images

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Hard and soft tissues with impacted lateral incisor

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Enucleated specimen with embedded canine

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Cystic lesion

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Tan colored thickenings in wall of cystic lesion


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Maxillary right quadrant

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Mandibular left quadrant

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Extracted tooth and pathologic lining

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Cyst and cholesterol granuloma

Cyst and cholesterol granuloma

Stratified squamous epithelium

Stratified squamous epithelium

Cyst epithelium

Cyst epithelium

Inflamed cyst

Inflamed cyst

Variable cyst epithelial lining

Variable cyst epithelial lining

Subepithelial mineralization

Subepithelial mineralization


Dentinogenic ghost cell tumor
Radiology images

Contributed by Brenda L. Nelson, D.D.S., M.S. and Kelly Magliocca, D.D.S., M.P.H.
Unilocular lesion Unilocular lesion

Unilocular lesion

Axial CT

Axial CT

Gross images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Cross sections of mandible tumor

Cross sections of mandible tumor

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H., Brenda L. Nelson, D.D.S., M.S. and Anne McLean, D.M.D.
Dentinogenic ghost cell tumor

Dentinogenic ghost cell tumor

DGCT with calcifications and squamous morules

Calcifications and squamous morules

Ghost cells

Ghost cells

Microcyst formation Microcyst formation

Microcyst formation


Ghost cells and dentinoid Ghost cells and dentinoid

Ghost cells and dentinoid

Beta catenin

Beta catenin



Eruption cyst
Clinical images

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Large eruption cyst

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Eruption cyst associated with #11

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Exposure of #11 crown

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Eruption cyst of #13


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Eruption cyst (arrow) of #44

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Eruption cyst of #21

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Eruption cyst to left lower second molar


Ghost cell odontogenic carcinoma
Clinical images

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Diffused swelling on the left side of face obliterating the nasolabial fold

Clinical and MRI examination

Axial section CT scan

Microscopic (histologic) images

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Ameloblastoma-like areas

Ghost cells

Cytologic atypia with increased mitotic rate

Ghost cells


Gingival cyst (adult)
Clinical images

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Gingival cyst of adult

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Clinical presentation

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Surgical exposure

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Bone defect after excision

Gross images

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Excised lesion

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Gingival cyst

Gingival cyst



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Thin stratified squamous epithelium

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Gingival cyst histology


Gingival cyst (newborn)
Clinical images

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Palatal cyst of newborn

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Gingival cyst of newborn


Glandular odontogenic cyst
Radiology images

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Large osteolytic lesion/s

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Well defined unilocular radiolucent lesion

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Well defined unilocular lesion

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Multilocular radiolucency in anterior mandible

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Large well defined radiolucency


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Oval radiolucency in anterior maxilla

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Well defined radiolucency

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Large multilocular radiolucency

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Complex lytic lesion of the anterior mandible

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Destructive
multilocular
lesion of the
anterior mandible

Clinical images

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Swelling over left middle third of face

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Intraoral swelling over left maxilla

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Well defined swelling on right side of face

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Lesion still attached to floor of maxillary sinus

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Fluctuant swelling extending from 19 to 29 regions

Gross images

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Excised lesion showing the cystic lining

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Glandular odontogenic cyst

Glandular odontogenic cyst



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Complex cyst lining

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Cystic lining with connective tissue stroma

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Pseudostratified squamous epithelium

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Islands of epithelium

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Mucous cells, epidermoid cells, and clear cells


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Glandular cystic lining

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Mucicarmine positive mucus cells

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Mucus cells (mucicarmine positive)


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Parakeratinized squamous epithelial lining

Eosinophilic cuboidal cells

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Vacuolated area in lining of a dentigerous cyst

Mucoepidermoid carcinoma-like islands in cyst wall


Inflammatory collateral cyst
Radiology images

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Well defined semilunar shaped radiolucency

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Expansion of vestibular cortical bone

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Radiolucency in distal follicular space of first permanent molar

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Hypodense area in vestibular region

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Axial CT



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Expansion of vestibular bone

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Radiolucency demarcated by fine radiopaque line

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Well defined ovoid radiolucency

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Buccal bifurcation cyst

Clinical images

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Intraoral preoperative view

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Intraoperative view of enucleation

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Inflammatory collateral cysts

Inflammatory collateral cysts



Images hosted on other servers:
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Various images


Juvenile trabecular ossifying fibroma and psammomatoid ossifying fibroma
Radiology images

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Radiolucent lesion in the right maxilla

Large radiolucent area on right side of molar

Mixed radio-opaque and radiolucent lesion

CT scan

Radiolucent lesion with central radiopacities

Expansile lesion of the left frontal sinus

Clinical images

Images hosted on other servers:

Well defined swelling obliterating the vestibule

Bony hard swelling with vestibular obliteration

Swelling angle ramus area of the mandible

Microscopic (histologic) images

Contributed by Kelly R. Magliocca, D.D.S., M.P.H.
Juvenile trabecular ossifying fibroma Juvenile trabecular ossifying fibroma Juvenile trabecular ossifying fibroma

Juvenile trabecular ossifying fibroma



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Mineralized pieces in the form of trabeculae

Extensive osteoid production

Cellular
connective tissue
with spherical
ossicles

Focally fused ossicles

Structures having
basophilic in center
and eosinophilic
in periphery


Langerhans cell histiocytosis
Diagrams / tables

Images hosted on other servers:
Pathogenesis of Langerhans cell histiocytosis

Pathogenesis of LCH

Radiology images

Contributed by Nasir Ud Din, M.B.B.S.
Plain Xray of skull

Plain Xray of skull

CT of brain without contrast

CT of brain without contrast

MRI of brain postcontrast MRI of brain postcontrast

MRI of brain postcontrast



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Sagittal T1 weighted contrast-enhanced brain MRI

Coronal CT / sagittal T1 weighted contrast enhanced MRI

MRI with contrast

MRI with contrast

Clinical images

Contributed by Molly Housley Smith, D.M.D.
Gingival swelling

Gingival swelling



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Orbital mass

Orbital mass

Microscopic (histologic) images

Contributed by Nasir Ud Din, M.B.B.S.
Eosinophil rich lesion

Eosinophil rich lesion

Multinucleated giant cells

Multinucleated giant cells

Characteristic LCH cells

Characteristic LCH cells

CD1a

CD1a

CD68

CD68

Cyclin D1

Cyclin D1

Electron microscopy images

Contributed by Mark R. Wick, M.D.
Birbeck granules

Birbeck granules

Molecular / cytogenetics images

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BRAF mutation analysis

BRAF mutation analysis

Videos

Radiology and histopathology descriptions


Lateral periodontal cyst and botryoid odontogenic cyst
Radiology images

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Tear dropshaped radiolucency

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Orthopantamograph

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Healing after 6 months

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Radicular triangular radiolucency

Clinical images

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Intra oral swelling

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Buccal cortical plate perforation

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Lateral periodontal cyst

Lateral periodontal cyst



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Thick lining of a lateral periodontal cyst

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Fragmented lining of a Botryoid odontogenic cyst

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Typical luminal excrescence

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Cystic lumen


Lymphoma
Radiology images

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Panoramic

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Primary NHL

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Axial and coronal section

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Coronal CT

Clinical images

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Intra-oral

Microscopic (histologic) images

Images hosted on PathOut server:
"Starry sky"

"Starry sky"



Images hosted on other servers:
Malignant lymphocytes

Malignant lymphocytes

DLBCL: CD20, CD10, BCL6, CD3

DLBCL: CD20, CD10, BCL6, CD3

Plasmablastic: CD20, CD138

Plasmablastic: CD20, CD138

Myeloma plasma cells

Myeloma plasma cells


Medication related osteonecrosis of jaw
Clinical images

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Various cases

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Osseous involvement


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Due to prosthesis

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After tooth extraction

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Maxillary involvement

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Osteolytic lesion in mandible

Gross images

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Segmental mandibulectomy
and surgical defect
Microscopic (histologic) images

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Osteolytic pattern

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Destruction of alveolar bone process

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Mandibular alveolar bone exposed

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Right maxillary exposed bone

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Generalized sclerotic changes


Melanotic neuroectodermal tumor of infancy
Radiology images

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Presence of bone erosion

Heterogenously enhancing soft tissue mass lesion

Radiolucent expansile, solid lesion

Clinical images

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Swelling on maxillary alveolus

Upper vestibule, alveolar ridge and anterior hard palate

Gross images

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Excised tumor

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H. and Karen Fritchie, M.D.
Melanotic neuroectodermal tumor of infancy Melanotic neuroectodermal tumor of infancy Melanotic neuroectodermal tumor of infancy

Melanotic neuroectodermal tumor of infancy

AE1 / AE3

AE1 / AE3

HMB45

HMB45


Metastases
Radiology images

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Orthopantogram
(panoramic view)

CT

3D CT

Clinical images

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Well defined solitary swelling on right side of mandible

Swelling in lower third of face

Intra-oral view

Microscopic (histologic) images

Images hosted on other servers:

Lung metastases


Breast metastasis

Renal cell carcinoma metastasis

Thyroid metastasis


Nasopalatine duct cyst
Radiology images

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Heart shaped radiolucent lesion

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Expansile maxillary alveolus

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Well defined round radiolucent area

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Well defined radiolucency


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Homogeneous high intensity area

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Saggital / axial CT images

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Axial sections of CT

Clinical images

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Intraoral swelling

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Intraoperative view, cystic area

Gross images

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Surgical specimen

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Nasopalatine duct cyst

Nasopalatine duct cyst



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Stratified squamous and pseudostratified columnar epithelium

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Flattened cuboidal epithelium

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Fibrous cyst wall with nerves


Odontoameloblastoma
Radiology images

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Cystic lesion

Diffuse foci of radiopacities

Gross images

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Surgical specimens

Microscopic (histologic) images

Contributed by David Cohen, M.B.B.Ch., M.D. (Case #367)
Case of the Week #367 Case of the Week #367 Case of the Week #367 Case of the Week #367 Case of the Week #367 Case of the Week #367

Case of the Week #367



Images hosted on other servers:
Various images Various images

Various images

Odontogenic epithelial cells

Odontogenic epithelial cells

Irregular masses of dysplastic dentin

Irregular masses of dysplastic dentin


Odontogenic / jaw cysts overview
Videos

Eruption of teeth

Tooth development

Tooth development


Odontogenic fibroma
Radiology images

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IOPA showing irregular radiopaque masses

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Multilocular radiolucency near 21, 22, 63, 24 and 25

Clinical images

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Gingival masses

Gross images

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Surgical intervention of odontogenic fibroma

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Odontogenic fibroma

Odontogenic fibroma

Case 1: Odontogenic fibroma with extensive calcification

Case 2: Odontogenic fibroma with giant cell reaction / giant cell granuloma


Case 3: Odontogenic fibroma



Images hosted on other servers:

Odontogenic fibroma of the maxilla

COF and dentigerous cyst in the maxilla

Islands of odontogenic epithelium within a cellular fibrous stroma


Features of peripheral odontogenic fibroma

Fig. 7 Odontogenic fibroma with central giant cell lesion

Fig. 8 Ossifying variant of COF

Fig. 9 Amyloid variant of COF


Odontogenic keratocyst
Radiology images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Sagittal CT anterior mandible

Sagittal CT anterior mandible

Axial CT left mandible

Axial CT left mandible

Axial CT anterior mandible

Axial CT anterior mandible

Coronal CT posterior mandible

Coronal CT posterior mandible


Coronal CT mandibular body

Coronal CT mandibular body

Cropped panorex left ramus

Cropped panorex left ramus

Cropped panorex body mandible

Cropped panorex body mandible

Clinical images

Images hosted on other servers:
Missing Image

Well circumscribed mass

Missing Image

Intraoral finding

Missing Image

Less common maxillary lesion

Gross images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Mandibular resection

Mandibular resection

Enucleation of mandibular lesion

Enucleation of mandibular lesion



Images hosted on other servers:
Missing Image

Cystic lesion with thin smooth wall

Missing Image

Massive KCOT

Missing Image

Impacted maxillary third molar

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H. and Case #503
Solid OKC

Solid OKC

Macrocystic

Macrocystic OKC

Peaks at surface layer

Peaks at surface layer

Smooth surface layer

Smooth surface layer

Corrugated surface layer

Corrugated surface layer

Inflamed attenuated epithelium

Inflamed attenuated epithelium


Odontogenic keratocyst

Basal layer hyperchromatism

Squamous lined cyst

Areas of inflammation / irritation

Classic microscopic features

Cytology images

Contributed by Kartik Viswanathan, M.D., Ph.D. and Kelly Magliocca, D.D.S., M.P.H.
Touch prep

Touch prep

Imprint touch prep

Imprint touch prep

Videos

Odontogenic keratocyst - histopathology


Odontogenic myxoma / fibromyxoma
Radiology images

Images hosted on other servers:
Multilocular, radiolucent lesion

Multilocular, radiolucent lesion

Right mandibular lateral occlusal view

Right mandibular lateral occlusal view

Multilocular radiolucent osteolytic lesion

Multilocular radiolucent osteolytic lesion

CT scan of mandible

CT scan of mandible

Clinical images

Images hosted on other servers:
Swelling on the right side

Swelling on the right side

Mandibular right quadrant

Mandibular right quadrant

Gray-white appearance

Gray-white appearance

Gross images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Mandibular myxoma resection

Mandibular myxoma resection



Images hosted on other servers:
Jelly-like appearance

Jelly-like appearance

Microscopic (histologic) images

Contributed by Abberly Lott Limbach, M.D. and Kelly Magliocca, D.D.S., M.P.H.
Myxoid background with bland spindle cells

Myxoid background with bland spindle cells

Bland spindle cells in myxoid stroma

Bland spindle cells in myxoid stroma

Inactive odontogenic rests

Inactive odontogenic rests


Maxilla neoplasm

Maxilla neoplasm

Mandibular lesion Mandibular lesion

Mandibular lesion

Mandibular lesion

Mandibular lesion


Odontogenic sarcoma / ameloblastic fibrosarcoma
Radiology images

Images hosted on other servers:
Missing Image

Ill-defined radiolucent lesion

Missing Image Missing Image

Panoramic radiographs

Missing Image

Multilocular radiolucent lesion

Missing Image

CT

Missing Image

Isodense area

Clinical images

Images hosted on other servers:
Missing Image

Gross swelling

Missing Image

Swelling, lower left mandible

Missing Image

Swelling without ulceration

Missing Image

Massive intraoral extension

Gross images

Images hosted on other servers:
Missing Image

Left half of mandible

Missing Image

Cross-section

Microscopic (histologic) images

Images hosted on other servers:
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Benign odontogenic epithelium

Missing Image

Odontogenic epithelium

Missing Image

Low grade malignant neoplasm

Missing Image

Small nests, islands

Missing Image

Epithelial dysplasia


Missing Image

AE1/AE3, vimentin, Ki67

Missing Image

PCNA, p53

Missing Image

Ki67, p53

Missing Image

Pan-cytokeratin, vimentin, Ki67


Odontoma
Radiology images

Images hosted on other servers:
Missing Image

Lesion in left side of the mandible

Missing Image

Compound odontoma and unerupted 32

Missing Image

Well defined multiple radiopacities

Missing Image

Radio opaque lesion surrounded by radiolucent zone

Clinical images

Images hosted on other servers:
Missing Image

Peripheral odontoma

Missing Image

Surgical site showing denticles

Missing Image

Mass in upper left maxillary region​​

Gross images

Images hosted on other servers:
Missing Image

Enucleated nine denticles

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Odontoma

Odontoma

Compound odontoma Compound odontoma Compound odontoma

Compound odontoma


Complex odontoma Complex odontoma Complex odontoma Complex odontoma

Complex odontoma


Orthokeratinized odontogenic cyst
Radiology images

Contributed by Nasir Ud Din, M.B.B.S.
OOC right mandible OOC right mandible

Right mandible

Clinical images

Images hosted on other servers:

Extraoral swelling

Obliterated buccal sulcus

Gross images

Images hosted on other servers:

Cyst lining envelops crown of tooth

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H. and Nasir Ud Din, M.B.B.S.
Orthokeratinized odontogenic cyst

Orthokeratinized odontogenic cyst

Cyst wall fragments Cyst wall fragments

Cyst wall fragments

Cyst wall lumen

Cyst wall lumen


Cyst wall fragments Cyst wall fragments

Cyst lining

Cyst wall fragments

Cyst lining



Osteoradionecrosis
Radiology images

Images hosted on other servers:
Missing Image

Osteoradionecrosis

Clinical images

Images hosted on other servers:
Missing Image

Mandibular osteonecrosis


Osteosarcoma
Clinical images
Images hosted on other servers:

Swelling and extension over left zygomatic region

Swelling in left
premaxillary
region with upper
lip protrusion

Computed tomography axial section

Axial CT scan of maxilla showing expansive infiltrative lesion

Osteosarcoma involving right ramus mandibula

Lytic and destructive
lesion in the left maxillary
tuber and molar tooth
area with root resorption

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Osteosarcoma, NOS

Osteosarcoma, NOS



Case of the Week #350: chondroblastic osteosarcoma of maxilla




Contributed by Dr. Kelly Magliocca and Dr. Anthony Martinez:

Arrows = inferior
border of
the mandible;
Arrowheads =
osteosarcoma

4× (same as first image, without arrows)

40×

100×

200×

400×



Images hosted on other servers:

Chondroid tissue with areas of osseous differentiation

Chondrocytes with
hyperchromatic
and pleomorphic
nuclei

Photomicrograph showing tumor osteoid areas

a) Large osteosarcoma involv-
ing mandible ramus and body
b) Classic chondroblastic
osteosarcoma of the jaw


Various images


Periapical (dental) granuloma
Radiology images

Images hosted on other servers:

(B) Periapical granuloma

Microscopic (histologic) images

Images hosted on other servers:

Early periapical granuloma

Intermediate periapical granuloma

Late periapical granuloma


Peripheral giant cell granuloma
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Peripheral giant cell granuloma

Peripheral giant cell granuloma


Primary intraosseous carcinoma, NOS
Radiology images

Images hosted on PathOut server:
Missing Image

Lytic and cystic lesion involving right mandible

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Primary intraosseous carcinoma, NOS

Primary intraosseous carcinoma, NOS



Images hosted on PathOut server:
Missing Image Missing Image Missing Image Missing Image

Verrucous carcinoma

Missing Image Missing Image

Cyst lining with chronic inflammation


Radicular (periapical) cyst
Diagrams / tables
N/A
Radiology images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Anterior maxillary lesion

Anterior maxillary lesion

Maxillary cyst

Maxillary cyst

Panorex molar root tips

Panorex molar root tips

Mesial root of molar

Mesial root of molar


Anterior maxilla root canal

Anterior maxilla root canal

Anterior mandible root canal

Anterior mandible root canal

Posterior maxilla intraoral

Posterior maxilla intraoral

Posterior mandible residual lesion

Posterior mandible residual lesion

Clinical images

Images hosted on other servers:
Missing Image

Palatal swelling

Missing Image

Lateral mandibular lesion

Gross images
N/A
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Necrotic tooth root

Necrotic tooth root

Root apex

Root apex

Cyst to apex

Cyst to apex

Apex with abscess

Apex with abscess

Cyst epithelium

Cyst epithelium

Cystic strips

Cystic strips


Nonkeratinized cyst epithelium

Nonkeratinized cyst epithelium

Arcades

Arcades

Posterior maxillary cyst

Posterior maxillary cyst

Root, bacteria and cyst

Root, bacteria and cyst

Bacteria present

Bacteria present

Partial keratinization

Partial keratinization


Prior root canal treatment

Prior root canal treatment

Epithelial arcades

Epithelial arcades

Granular foreign material

Granular foreign material

Splendore-Hoeppli phenomenon

Splendore-Hoeppli phenomenon

Cystic sac

Cystic sac

Bacteria within lumen

Bacteria within lumen


Rushton bodies in epithelium

Rushton bodies in epithelium

Amorphous Rushton bodies

Amorphous Rushton bodies

Hairpin/polycyclic Rushton bodies

Hairpin / polycyclic Rushton bodies

Refractile appearance

Refractile appearance

Refractile appearance

Pulse granuloma in wall

Squamous epithelial lined cyst

Squamous epithelial lined cyst

Cytology images
N/A
Electron microscopy images
N/A
Molecular / cytogenetics images
N/A
Videos
N/A

Radicular (periapical) cyst
Radiology images

Images hosted on other servers:
Missing Image

Radicular cyst

Missing Image

Radicular cyst, root partially reabsorbed

Missing Image

Upper maxilla

Missing Image

Periapical cyst involving maxillary anteriors

Missing Image

Progressive involution of periapical lesion

Clinical images

Images hosted on other servers:
Missing Image

Palatal swelling

Missing Image

Lateral mandibular lesion

Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Radicular cyst

Radicular cyst



Images hosted on other servers:
Missing Image

H&E

Missing Image

Cyst

Missing Image

H&E


Residual cyst
Radiology images

Images hosted on other servers:
Missing Image

Residual jaw cyst


Sclerosing odontogenic carcinoma
Radiology images

Images hosted on other servers:

Infiltrative ground glass radiolucency

Clinical images

Images hosted on other servers:

Anterior mandible exophytic mass

Gross images

Images hosted on other servers:

Mandible tumor involving skin

Microscopic (histologic) images

Contributed by Nathan Lee, D.M.D.

Architectural invasion

Bland cytology

Hypercellular tumor

Invasive clear cells

Hypercellular clear cell variant

Bland clear cells



Pankeratin

CK7

CK20

p63



Secondary chronic
Clinical images

Images hosted on other servers:
Missing Image

Extracion of tooth 46

Missing Image

Mandibular swelling


Simple bone cyst
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Simple bone cyst Simple bone cyst

Simple bone cyst


Squamous odontogenic tumor
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Squamous odontogenic tumor

Squamous odontogenic tumor

SOT at scanning magnification

SOT at scanning magnification

Benign islands of squamous epithelium within fibrous stroma Benign islands of squamous epithelium within fibrous stroma

Benign islands of squamous epithelium within fibrous stroma


Epithelial vacuolization of squamous islands

Epithelial vacuolization of squamous islands

Intraepithelial calcifications

Intraepithelial calcifications

Rounded contours of nests

Rounded contours of nests


Surgical ciliated cyst
Microscopic (histologic) images

Contributed by Anthony Chi, M.D., Ph.D.
Cystic lesion in maxilla, intraosseous

Cystic lesion in maxilla, intraosseous

Columnar epithelial lining

Columnar epithelial lining

Prominent cilia

Prominent cilia

Cyst with thin wall in maxilla, intraosseous

Cyst with thin wall in maxilla, intraosseous

Ciliated cyst lining

Ciliated cyst lining

No cytologic atypia

No cytologic atypia


WHO classification
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Adenomatoid odontogenic tumor

Adenomatoid odontogenic tumor

Ameloblastic carcinoma Ameloblastic carcinoma

Ameloblastic carcinoma

Ameloblastic fibroma

Ameloblastic fibroma



Ameloblastoma

Ameloblastoma

Ameloblastoma, extraosseous / peripheral type

Ameloblastoma, extraosseous / peripheral type

Ameloblastoma, unicystic type

Ameloblastoma, unicystic type

Aneurysmal bone cyst

Aneurysmal bone cyst

Calcifying epithelial odontogenic tumor

Calcifying epithelial odontogenic tumor

Calcifying odontogenic cyst

Calcifying odontogenic cyst



Cemento-osseous dysplasia

Cemento-osseous dysplasia

Cementoblastoma

Cementoblastoma

Central giant cell granuloma

Central giant cell granuloma

Cherubism

Cherubism

Chondrosarcoma

Chondrosarcoma

Clear cell odontogenic carcinoma

Clear cell odontogenic carcinoma



Dentigerous cyst

Dentigerous cyst

Dentinogenic ghost cell tumor

Dentinogenic ghost cell tumor

Desmoplastic fibroma

Desmoplastic fibroma

Fibrous dysplasia

Fibrous dysplasia

Gingival cyst

Gingival cyst

Glandular odontogenic cyst

Glandular odontogenic cyst



Inflammatory collateral cysts

Inflammatory collateral cysts

Lateral periodontal cyst

Lateral periodontal cyst

Melanotic neuroectodermal tumor of infancy

Melanotic neuroectodermal tumor of infancy

Nasopalatine duct cyst

Nasopalatine duct cyst

Odontogenic fibroma

Odontogenic fibroma

Odontogenic keratocyst

Odontogenic keratocyst



Odontogenic myxoma / myxofibroma

Odontogenic myxoma / myxofibroma

Odontogenic sarcomas

Odontogenic sarcoma

Odontoma

Odontoma

Orthokeratinized odontogenic cyst

Orthokeratinized odontogenic cyst

Ossifying fibroma

Ossifying fibroma

Osteoma

Osteoma



Osteosarcoma, NOS

Osteosarcoma, NOS

Peripheral giant cell granuloma

Peripheral giant cell granuloma

Primary intraosseous carcinoma, NOS

Primary intraosseous carcinoma, NOS

Primordial odontogenic tumor

Primordial odontogenic tumor

Radicular cyst

Radicular cyst



Simple bone cyst Simple bone cyst

Simple bone cyst

Solitary plasmacytoma of bone

Solitary plasmacytoma of bone

Squamous odontogenic tumor

Squamous odontogenic tumor

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Recent Mandible & maxilla Pathology books

Gnepp: 2021

IARC: 2024

Neville: 2023

Speight: 2022

Stelow: 2020

Thompson: 2022

Wenig: 2017

Wenig: 2024



Find related Pathology books: head & neck/endocrine
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