Adrenal gland and paraganglia
Other adrenal malignancies
Ewing sarcoma / PNET

Author: Nat Pernick, M.D. (see Authors page)

Revised: 21 January 2016, last major update February 2005

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Ewing sarcoma [title] adrenal
Definition / General
  • 11 year old boy with adrenal mass who died 15 months after presentation, despite aggressive treatment (Hum Pathol 2001;32:1012)
Micro Description
  • Monotonous primitive round cells resembling neuroblastoma
Positive Stains
Molecular / Cytogenetics Description
  • t(11;22)(q24;q12) and EWS-FLI1 gene fusion product
Differential Diagnosis
  • Neuroblastoma: MIC2 / CD99 negative, no Ewing / PNET translocation