Adrenal gland and paraganglia
Other adrenal malignancies
Epithelioid angiosarcoma

Topic Completed: 1 February 2005

Revised: 10 June 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Epithelioid angiosarcoma [title] adrenal

See Also: Angiosarcoma

Nat Pernick, M.D.
Page views in 2018: 461
Page views in 2019 to date: 895
Cite this page: Pernick N. Epithelioid angiosarcoma. website. Accessed December 11th, 2019.
Definition / general
  • Rare
  • Median age 60 years, range 45 - 85 years
  • No gender preference
  • Aggressive, with death common due to lung metastases (Am J Surg Pathol 1994;18:62)
Case reports
  • Excision, chemotherapy
Gross description
  • 6 - 10 cm
  • May be cystic-solid
Microscopic (histologic) description
  • Sheets or nests of epithelioid cells between dilated anastomotic vascular spaces, lined by similar cells
  • Tumor cells have intracytoplasmic vacuoles occasionally containing red blood cells
Positive stains
Electron microscopy images
  • Rod-shaped microtubulated bodies, intracytoplasmic lumen
Differential diagnosis
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