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Adrenal gland and paraganglia

Congenital anomalies

Hereditary unresponsiveness to ACTH


Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 6 February 2013, last major update February 2005
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

General
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● Rare; due to abnormalities of ACTH receptor in adrenocortical cells
● Seizures, hypoglycemia, muscle weakness and hyperpigmentation similar to Addison’s disease
● Low plasma cortisol levels, increased serum ACTH

Micro description
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● Normal zona glomerulosa, atrophic zona fasciculata and reticularis

End of Adrenal gland and paraganglia > Congenital anomalies > Hereditary unresponsiveness to ACTH


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