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General
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Terminology
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Epidemiology
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Sites
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Etiology
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Clinical features
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Diagnosis
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Laboratory
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Radiology
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Prognostic factors
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Case reports
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Treatment
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Gross description
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Gross images
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Adrenal ganglioneuroma

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Ganglio-neuroblastoma

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Composite ganglioneuroma
and pheochromocytoma



Ganglioneuroblastoma, images courtesy of Dr. Carmen Perrino and Dr. Debra Zynger:

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Stroma-rich, intermixed type

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Focal undifferentiated component

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Stroma-rich, nodular type

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With treatment-related changes

Micro description
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Micro images
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Adrenal neuroblastoma

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Ganglioneuroma: vimentin+, synaptophysin+, S100+

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Composite tumor, ganglioneuroma and pheochromocytoma



Ganglioneuroblastoma, images courtesy of Dr. Carmen Perrino and Dr. Debra Zynger:

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Neuroblast cell component

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Numerous ganglion cells

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Homer Wright pseudorosettes

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Vaguely formed Homer Wright pseudorosettes

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Hemorrhagic component

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Stroma-rich, nodular type

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Focal undifferentiated component and calcification

Virtual slides (all from adrenal gland)
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Neuroblastoma

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Neuroblastoma, cystic

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Neuroblastoma metastatic to skull (left), neck (right)

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Ganglioneuroblastoma, right is therapy-associated

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Adrenal and retroperitoneal ganglioneuro-
blastoma

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Adrenal gland ganglioneuroma

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Adrenal gland pheochromocy-
toma, focus of ganglioneuroma

Cytology description
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Cytology images
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Ganglioneuroma of the neck, Schwann cells and ganglion cells

Positive stains
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Negative stains
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Molecular / cytogenetics description
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Differential diagnosis
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End of Adrenal gland and paraganglia > Neuroblastic tumors > General



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