Adrenal gland and paraganglia
Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 22 March 2013, last major update February 2005
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
- Usually in carotid bodies (may be due to chronic hypoxemia); associated with high altitude, chronic obstructive pulmonary disease, systemic hypertension, cystic fibrosis and cyanotic congenital heart disease
- May also affect vagal and aorticopulmonary paraganglia
- Weight over 30g, diameter > 5 mm
- Increased number of lobules, some confluent, composed of increased numbers of sustentacular cells and chief cells with hyperchromatic and mildly enlarged nuclei
End of Adrenal gland and paraganglia > Paraganglia > Hyperplasia
- Paraganglioma: usually > 300 mg, have higher density of chief cells
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