Adrenal gland and paraganglia
Paraganglia
Pigmented paraganglioma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 21 January 2016, last major update February 2005

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PubMed Search: Pigmented [title] paraganglioma

Related: Paraganglioma, general, Aorticopulmonary, Carotid body, Cauda equina, Jugulotympanic, Laryngeal
Cite this page: Pigmented paraganglioma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/adrenalparagangliomapigmented.html. Accessed December 14th, 2018.
Definition / general
  • Rare
Case reports
Gross description
  • Jet-black or no gross evidence of pigmentation
Microscopic (histologic) description
  • Pigment consistent with neuromelanin, a waste product of catecholamine metabolism
Electron microscopy description
  • Dense core neurosecretory granules, usually melanosomes or premelanosomes
  • Case report above had abundant large pleomorphic electron dense granules consistent with lipofuscin or neuromelanin
Differential diagnosis