Adrenal gland and paraganglia
Pheochromocytoma / paraganglioma
Staging



Topic Completed: 1 August 2017

Revised: 6 June 2019

Copyright: 2017-2019, PathologyOutlines.com, Inc.

PubMed search: Staging[TIAB] pheochromocytoma paraganglioma


Debra Zynger, M.D.
Page views in 2018: 1,063
Page views in 2019 to date: 683
Cite this page: Zynger D. Pheochromocytoma and paraganglioma - staging. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/adrenalpheostaging.html. Accessed June 17th, 2019.

Pathologic TNM staging of pheochromocytoma / paraganglioma, AJCC 8th edition
Primary tumor (pT)
  • pTX: Primary tumor cannot be assessed
  • pT1: Pheochromocytoma < 5 cm
  • pT2: Pheochromocytoma 5 cm or larger OR sympathetic paraganglioma
  • pT3: Invasion into surrounding tissues (including extra-adrenal adipose)
Regional lymph nodes (pN)
Includes aortic and retroperitoneal nodes for abdominal and pelvic tumors
  • pNX: Regional lymph nodes cannot be assessed
  • pN0: No regional lymph node metastasis
  • pN1: Regional lymph node metastasis
Distant metastasis (pM)
  • pM1a: Metastasis to bone
  • pM1b: Metastasis to nonregional lymph node, liver or lung
  • pM1c: Metastasis to bone and multiple other sites
AJCC prognostic stage groups
  • Stage I: T1 N0 M0
  • Stage II: T2 N0 M0
  • Stage III: T1 N1 M0 or T2 N1 M0 or T3 N0-1 M0
  • Stage IV: T1-3 N0-1 M1
Gross images

Contributed by Debra Zynger, M.D.

pT1 tumor < 5 cm

pT2 tumor ≥ 5 cm

Microscopic (histologic) images

Contributed by Debra Zynger, M.D.

pT3 tumor with extra-adrenal adipose invasion

pT3 tumor with invasion of the kidney

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