Adrenal gland and paraganglia
Adrenal union or adhesion
Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 6 February 2013, last major update February 2005
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
Adrenal union (fusion)
● Adrenal glands are fused above the aorta with butterfly or horseshoe shape, with common connective tissue capsule and intermingling of cells
● Associated with midline congenital defects, including spinal dysraphism, indeterminate visceral situs, bilateral renal agenesis and Cornelia de Lange syndrome (mental and growth retardation, low set ears, antiverted nostrils, spade-like hands with short tapering fingers)
● Normal histology
● Unions also to kidney or liver in 0.4-3.0% of unselected autopsies; common capsule, but no intermingling of cells
● Adrenal gland is attached to opposite adrenal gland, but with an intervening connective tissue capsule
End of Adrenal gland and paraganglia > Congenital anomalies > Adrenal union or adhesion
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