Table of ContentsDefinition / General
Cite this page: Frozen section. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ampullafrozensection.html. Accessed October 23rd, 2016.
Definition / General
- Major criteria for malignancy are nuclear size variation of at least 4:1 between ductal epithelial cells, incomplete ductal lumens, disorganized duct distribution
- Minor criteria are huge, irregular epithelial nucleoli, necrotic glandular debris, glandular mitoses, glands unaccompanied by connective tissue stroma within smooth muscle bundles, perineural invasion (Am J Surg Pathol 1981;5:179)