Ampulla of Vater
Miscellaneous
Frozen section

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 24 February 2016, last major update December 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: Frozen section[title]
Table of Contents
Definition / General
Cite this page: Frozen section. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ampullafrozensection.html. Accessed December 6th, 2016.
Definition / General
  • Major criteria for malignancy are nuclear size variation of at least 4:1 between ductal epithelial cells, incomplete ductal lumens, disorganized duct distribution
  • Minor criteria are huge, irregular epithelial nucleoli, necrotic glandular debris, glandular mitoses, glands unaccompanied by connective tissue stroma within smooth muscle bundles, perineural invasion (Am J Surg Pathol 1981;5:179)