Ampulla of Vater
Frozen section

Topic Completed: 1 December 2012

Revised: 27 June 2019

Copyright: 2003-2019,, Inc.

PubMed Search: Frozen section[title]

Hanni Gulwani, M.B.B.S.
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Table of Contents
Definition / general
Cite this page: Gulwani H. Frozen section. website. Accessed December 13th, 2019.
Definition / general
  • Major criteria for malignancy are nuclear size variation of at least 4:1 between ductal epithelial cells, incomplete ductal lumens, disorganized duct distribution
  • Minor criteria are huge, irregular epithelial nucleoli, necrotic glandular debris, glandular mitoses, glands unaccompanied by connective tissue stroma within smooth muscle bundles, perineural invasion (Am J Surg Pathol 1981;5:179)
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