Frozen section

Ampulla of Vater
Miscellaneous
Frozen section

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 24 February 2016, last major update December 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: Frozen section[title]

Table of Contents

Definition / General

Major criteria for malignancy are nuclear size variation of at least 4:1 between ductal epithelial cells, incomplete ductal lumens, disorganized duct distribution
Minor criteria are huge, irregular epithelial nucleoli, necrotic glandular debris, glandular mitoses, glands unaccompanied by connective tissue stroma within smooth muscle bundles, perineural invasion (Am J Surg Pathol 1981;5:179)