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Ampulla of Vater


Hyperplastic polyp

Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 11 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.


● Similar to serrated polyps in colorectum (Hum Pathol 2011;42:1953)
● Rare, occur in second part of duodenum and ampulla
● Usually incidentally detected, mean age 50 yrs
● Uncertain malignant potential

Positive stains

● MUC6 expression in crypt bases

End of Ampulla of Vater > Benign/non-neoplastic > Hyperplastic polyp

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