Ampulla of Vater
Carcinoma
Mixed acinar-endocrine carcinoma


Topic Completed: 01 December 2012

Revised: 11 January 2019

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PubMed Search: Mixed acinar-endocrine carcinoma
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Cite this page: Gulwani H. Mixed acinar-endocrine carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ampullamixedacinarendocrine.html. Accessed January 22nd, 2019.
Definition / general
  • May arise in heterotopic pancreatic cells
  • Acinar cell carcinoma component is composed of pancreatic acinar cells with zymogen granules on EM
Case reports
Microscopic (histologic) description
  • Nests of tumor cells with acinar structures and endocrine immunoreactivity and endocrine granules on EM
Microscopic (histologic) images

Images hosted on other servers:

Various images

Positive stains
  • Amylase, trypsin, synaptophysin
Electron microscopy description
  • Endocrine and zymogen granules