Ampulla of Vater
Mixed acinar-endocrine carcinoma

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 5 February 2016, last major update December 2012

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Mixed acinar-endocrine carcinoma
Cite this page: Mixed acinar-endocrine carcinoma. website. Accessed October 20th, 2018.
Definition / general
  • May arise in heterotopic pancreatic cells
  • Acinar cell carcinoma component is composed of pancreatic acinar cells with zymogen granules on EM
Case reports
Microscopic (histologic) description
  • Nests of tumor cells with acinar structures and endocrine immunoreactivity and endocrine granules on EM
Microscopic (histologic) images

Various images

Positive stains
  • Amylase, trypsin, synaptophysin
Electron microscopy description
  • Endocrine and zymogen granules