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Ampulla of Vater


Neuroendocrine tumors - staging

Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 11 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

Primary tumor (T)

TX: Primary tumor cannot be assessed
T0: No evidence of primary tumor
T1: Tumor invades lamina propria or submucosa and tumor size 1 cm or less
T2: Tumor invades muscularis propria or tumor size >1 cm
T3: Tumor invades through the muscularis propria into pancreas or retroperitoneum (ampullary or duodenal tumors) or into nonperitonealized tissues
T4: Tumor invades visceral peritoneum (serosa) or invades other organs

● For any T, add (m) for multiple tumors

Regional lymph nodes (N)

NX: Regional lymph nodes cannot be assessed
N0: No regional lymph node metastasis
N1: Regional lymph node metastasis

Distant Metastasis (M)

M0: No distant metastasis
M1: Distant metastasis

Anatomic stage / prognostic groups

Stage I: T1 N0 M0
Stage IIA: T2 N0 M0
Stage IIB: T3 N0 M0
Stage IIIA: T4 N0 M0
Stage IIIB: Any T N1 M0
Stage IV: M1 (any T, any N)

Additional references

Virchows Arch 2006;449:395, Staging form

End of Ampulla of Vater > Carcinoma > Neuroendocrine tumors - staging

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