Table of ContentsDefinition / general
Cite this page: Pernick, N. Highly differentiated squamous lesion. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/anusHDsqlesion.html. Accessed December 15th, 2017.
Definition / general
- Highly differentiated squamous lesion that appears to be invasive
- Composed of large, mature squamous cells except at base and edges, which have more undifferentiated cells with mitotic activity
- Epithelium is acanthotic and hyperkeratotic; lamina propria has lymphoplasmacytic infiltrate
- May be invasive but local excision appears to be curative