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Anus and perianal area

Premalignant lesions

Condyloma acuminatum

Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 15 April 2013, last major update April 2005
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.


● Associated with HPV 6, 11, 16, 18; also 31, 35, 39
● Associated with other HPV lesions (anal dysplasia / CIS, verrucous carcinoma, squamous cell carcinoma / basaloid carcinoma)

Gross description

● Papillary excrescences

Micro description

● Papillary squamous epithelium with hyperkeratosis, variable koilocytotic atypia
● Variable dysplastic changes

Differential diagnosis

Other HPV associated lesions:
Anal dysplasia / CIS
Squamous cell / basaloid carcinoma
Verrucous carcinoma

End of Anus and perianal area > Premalignant lesions > Condyloma acuminatum

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