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Anus and perianal area

Benign or non-neoplastic lesions

Hypertrophic HSV in HIV+ patients


Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 15 April 2013, last major update April 2005
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● Rare chronic hyperproliferative plaque or mass that clinically resembles malignancy

Case reports
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● 44 year old man with a hypertrophic gluteal cleft plaque (J Drugs Dermatol 2003;2:198)
● Woman with a large, fungated vulvar mass that clinically was thought to be malignant; biopsies showed only acanthosis and inflammation (Case of the Week #53)

Treatment
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● Often ineffective, often recurs

Clinical images
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Vulvar mass

Micro description
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● Epithelial hyperplasia, brisk infiltrate of lymphocytes and plasma cells (BHIVA Conf 2005;11:PA8)

Micro images
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Various images of vulvar mass


HSV immunostain

Positive stains
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● HSV (Dis Colon Rectum 2005;48:2289)

End of Anus and perianal area > Benign or non-neoplastic lesions > Hypertrophic HSV in HIV+ patients


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