Inflammatory cloacogenic polyp

Anus and perianal area
Benign or nonneoplastic lesions
Inflammatory cloacogenic polyp

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 3 October 2017, last major update November 2014

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Inflammatory cloacogenic polyp

Table of Contents

Cite this page: Weisenberg, E. Inflammatory cloacogenic polyp. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/anusinflamcloaco.html. Accessed April 26th, 2018.

Definition / general

Middle aged patients with rectal bleeding
Single or multiple polyps in anal canal, resemble hemorrhoids
Associated with solitary rectal ulcer syndrome or mucosal prolapse; may be due to prolapse with ischemic damage and subsequent repair
Patients may also have HPV related disorders

Treatment

Excision

Gross description

Sessile, 1 - 2 cm

Microscopic (histologic) description

Tubulovillous with elongated, irregular crypts extending into submucosa (resembles colitis cystica profunda)
Squamous, colorectal or transitional epithelium, eroded at surface or covered with exudate (Am J Surg Pathol 1981;5:761)
May be hyperplastic or regenerative
Thickened muscularis mucosa with irregular strands penetrating lamina propria
No dysplastic changes, no desmoplasia, no invasion

Microscopic (histologic) images

Images hosted on PathOut server:

Contributed by Dr. Yvonne Bury, University Hospital of North Durham (UK)

Images hosted on other servers:

Low power

Left: H&E, right: PCNA

Differential diagnosis

Villous adenoma