Inflammatory cloacogenic polyp

Anus & perianal
Benign / nonneoplastic lesions
Inflammatory cloacogenic polyp

Author: Elliot Weisenberg, M.D.

Topic Completed: 1 November 2014

Revised: 20 August 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Inflammatory cloacogenic polyp

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Table of Contents

Cite this page: Weisenberg E. Inflammatory cloacogenic polyp. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/anusinflamcloaco.html. Accessed October 13th, 2019.

Definition / general

Middle aged patients with rectal bleeding
Single or multiple polyps in anal canal, resemble hemorrhoids
Associated with solitary rectal ulcer syndrome or mucosal prolapse; may be due to prolapse with ischemic damage and subsequent repair
Patients may also have HPV related disorders

Treatment

Excision

Gross description

Sessile, 1 - 2 cm

Microscopic (histologic) description

Tubulovillous with elongated, irregular crypts extending into submucosa (resembles colitis cystica profunda)
Squamous, colorectal or transitional epithelium, eroded at surface or covered with exudate (Am J Surg Pathol 1981;5:761)
May be hyperplastic or regenerative
Thickened muscularis mucosa with irregular strands penetrating lamina propria
No dysplastic changes, no desmoplasia, no invasion

Microscopic (histologic) images

Contributed by Dr. Yvonne Bury, University Hospital of North Durham (UK)

Various images

Images hosted on other servers:

Low power

Left: H&E, right: PCNA

Differential diagnosis

Villous adenoma