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General
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- Middle aged patients with rectal bleeding
- Single or multiple polyps in anal canal, resemble hemorrhoids
- Associated with solitary rectal ulcer syndrome or mucosal prolapse; may be due to prolapse with ischemic damage and subsequent repair
- Patients may also have HPV related disorders
Treatment
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Gross description
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Micro description
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- Tubulovillous with elongated, irregular crypts extending into submucosa (resembles colitis cystica profunda)
- Squamous, colorectal or transitional epithelium, eroded at surface or covered with exudate (Am J Surg Pathol 1981;5:761)
- May be hyperplastic or regenerative
- Thickened muscularis mucosa with irregular strands penetrating lamina propria
- No dysplastic changes, no desmoplasia, no invasion
Micro images
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Low power
Left: H&E, right: PCNA
Differential diagnosis
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End of Anus and perianal area > Benign or non-neoplastic lesions > Inflammatory cloacogenic polyp
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