Anus & perianal area
Other nonneoplastic
Inflammatory cloacogenic polyp
Author: Elliot Weisenberg, M.D.
Topic Completed: 1 November 2014
Minor changes: 20 August 2019
Copyright: 2002-2019, PathologyOutlines.com, Inc.
PubMed Search: Inflammatory cloacogenic polyp
Table of Contents
Definition / general | Treatment | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosisCite this page: Weisenberg E. Inflammatory cloacogenic polyp. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/anusinflamcloaco.html. Accessed August 11th, 2020.
Definition / general
- Middle aged patients with rectal bleeding
- Single or multiple polyps in anal canal, resemble hemorrhoids
- Associated with solitary rectal ulcer syndrome or mucosal prolapse; may be due to prolapse with ischemic damage and subsequent repair
- Patients may also have HPV related disorders
Treatment
- Excision
Gross description
- Sessile, 1 - 2 cm
Microscopic (histologic) description
- Tubulovillous with elongated, irregular crypts extending into submucosa (resembles colitis cystica profunda)
- Squamous, colorectal or transitional epithelium, eroded at surface or covered with exudate (Am J Surg Pathol 1981;5:761)
- May be hyperplastic or regenerative
- Thickened muscularis mucosa with irregular strands penetrating lamina propria
- No dysplastic changes, no desmoplasia, no invasion
Microscopic (histologic) images
Contributed by Dr. Yvonne Bury, University Hospital of North Durham (UK)
Various images
Images hosted on other servers:
Low power
Left: H&E, right: PCNA
Differential diagnosis
