Anus and perianal area
Carcinoma
Sarcomatoid carcinoma


Topic Completed: 1 November 2014

Revised: 17 January 2019

Copyright: (c) 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Sarcomatoid carcinoma [title] "loattrfree full text"[sb]
Page views in 2018: 275
Page views in 2019 to date: 53
Cite this page: Gonzalez RS. Sarcomatoid carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/anussarcomatoid.html. Accessed February 17th, 2019.
Definition / general
  • Rare epithelial malignancy of the anus with areas morphologically resembling sarcoma
Terminology
  • Also called spindle cell carcinoma or pseudosarcomatous carcinoma; "carcinosarcoma" has been used interchangeably but suggests true sarcomatous differentiation (Pathology 2006;38:264)
Epidemiology
  • Extremely rare in the anus, as in the colon
Case reports
Treatment
  • Surgery
Microscopic (histologic) description
  • Carcinoma with a well differentiated component (such as squamous cell carcinoma or adenocarcinoma) and a poorly differentiated component that resembles sarcoma (ie, spindle cell morphology) but demonstrates epithelial characteristics by immunohistochemistry or electron microscopy
Microscopic (histologic) images

Images hosted on other servers:

Anal biopsy

Positive stains
Differential diagnosis
  • Carcinosarcoma: biphasic tumor with an epithelial component and a truly mesenchymal component