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Appendix

Benign tumors

Granular cell tumor


Reviewer: Jaleh Mansouri, M.D. (see Reviewers page)
Revised: 20 October 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Similar to granular cell tumors at other sites, but uncommon in appendix

Case reports
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● 62 year old woman with submucosal rectosigmoid mass (J Gastrointestin Liver Dis 2009;18:475)

Micro description
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● Polygonal cells with granular cytoplasm and bland nuclei

Positive stains
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● S100, PAS

Differential diagnosis
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● Granular cell transformation of appendiceal smooth muscle: S100-

End of Appendix > Benign tumors > Granular cell tumor


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