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Appendix

Appendicitis

Adenovirus

Reviewer: Jaleh Mansouri, M.D. (see Reviewers page)
Revised: 20 October 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Associated with marked lymphoid hyperplasia leading to intussusception, usually in children
● Viral nuclear inclusions: basophilic nuclei with indistinct nuclear membranes (Cowdry type B, smudge cells) and, less commonly, eosinophilic inclusions surrounded by halos and distinct nuclear membranes (Cowdry type-A)
● Immunohistochemistry, PCR, and in situ hybridization helpful in diagnosis

Additional references
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● Infect Dis Clin North Am 2010;24:995

End of Appendix > Appendicitis > Adenovirus

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