Reviewer: Jaleh Mansouri, M.D. (see Authors page)

Revised: 15 February 2016, last major update August 2012

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Adenovirus appendix
Cite this page: Adenovirus. website. Accessed October 23rd, 2016.
Definition / General
  • Associated with marked lymphoid hyperplasia leading to intussusception, usually in children
  • Viral nuclear inclusions: basophilic nuclei with indistinct nuclear membranes (Cowdry type B, smudge cells) and, less commonly, eosinophilic inclusions surrounded by halos and distinct nuclear membranes (Cowdry type-A)
  • Immunohistochemistry, PCR, and in situ hybridization helpful in diagnosis