Topic Completed: 1 August 2012

Revised: 20 August 2019

Copyright: (c) 2003-2019,, Inc.

PubMed Search: Adenovirus appendix

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Page views in 2019 to date: 275
Cite this page: Mansouri J. Adenovirus. website. Accessed October 18th, 2019.
Definition / general
  • Associated with marked lymphoid hyperplasia leading to intussusception, usually in children
  • Viral nuclear inclusions: basophilic nuclei with indistinct nuclear membranes (Cowdry type B, smudge cells) and, less commonly, eosinophilic inclusions surrounded by halos and distinct nuclear membranes (Cowdry type-A)
  • Immunohistochemistry, PCR, and in situ hybridization helpful in diagnosis
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