Crohn's disease

Topic Completed: 1 August 2012

Minor changes: 20 August 2019

Copyright: (c) 2003-2019,, Inc.

PubMed Search: Crohn's disease appendix

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Cite this page: Mansouri J. Crohn's disease. website. Accessed May 29th, 2020.
Definition / general
  • Involves appendix in 25% of patients, may simulate acute appendicitis
  • Rare to initially or only involve the appendix
  • If limited to appendix, consider as granulomatous appendicitis; 90% of these patients do NOT develop disease elsewhere in GI tract

  • Diagnostic criteria:
    • Granulomas, transmural lymphoid aggregates, fissure-type ulcers
Differential diagnosis
  • Yersinia, Mycobacteria or Actinomyces infections
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