Appendix
Appendicitis
Crohn's disease


Topic Completed: 1 August 2012

Revised: 29 April 2019

Revised: 22 January 2019

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PubMed Search: Crohn's disease appendix
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Cite this page: Mansouri J. Crohn's disease. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/appendixcrohn.html. Accessed May 23rd, 2019.
Definition / general
  • Involves appendix in 25% of patients, may simulate acute appendicitis
  • Rare to initially or only involve the appendix
  • If limited to appendix, consider as granulomatous appendicitis; 90% of these patients do NOT develop disease elsewhere in GI tract

  • Diagnostic criteria:
    • Granulomas, transmural lymphoid aggregates, fissure-type ulcers
Differential diagnosis
  • Yersinia, Mycobacteria or Actinomyces infections
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