Appendix - Crohn’s disease

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Appendix

Appendicitis

Crohn’s disease

Reviewer: Jaleh Mansouri, M.D. (see Reviewers page)
Revised: 20 October 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Involves appendix in 25% of patients, may simulate acute appendicitis
● Rare to initially or only involve the appendix
● If limited to appendix, consider as granulomatous appendicitis; 90% of these patients do NOT develop disease elsewhere in GI tract

Diagnostic criteria
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● Granulomas, transmural lymphoid aggregates, fissure-type ulcers

Differential diagnosis
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● Yersinia, Mycobacteria or Actinomyces infections

End of Appendix > Appendicitis > Crohn’s disease

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