Appendix
General
Diverticulosis

Reviewer: Jaleh Mansouri, M.D., (see Authors page)

Revised: 26 January 2016, last major update August 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: Diverticulosis appendix
Definition / General
  • Uncommon, in 0.004% to 2% of appendectomies
  • More likely acquired than congenital
  • Usually multiple diverticuli (diverticula) if present
  • Due to increased intraluminal pressure and wall weakness
  • Present in 14% of cystic fibrosis patients vs. 1-2% of general population (Hum Pathol 1987;18:75)
  • Marker for presence of local/regional neoplasms (J Clin Pathol 2012;65:638)
  • May cause diverticulitis, which clinically resembles appendicitis
  • If associated with low grade mucinous lesions, may cause pseudomyxoma peritonei (Mod Pathol 2000;13:495
Gross Description
  • Usually < 5 mm
Micro Description
  • Herniation of mucosa and muscularis mucosa through wall of the appendix
Micro Images

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Diverticulum with cystadenoma