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Appendix

Diverticulosis

Reviewer: Jaleh Mansouri, M.D., (see Reviewers page)
Revised: 15 October 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Uncommon, in 0.004% to 2% of appendectomies
● More likely acquired than congenital
● Usually multiple diverticuli (diverticula) if present
● Due to increased intraluminal pressure and wall weakness
● Present in 14% of cystic fibrosis patients vs. 1-2% of general population (Hum Pathol 1987;18:75)
● Marker for presence of local/regional neoplasms (J Clin Pathol 2012;65:638)
● May cause diverticulitis, which clinically resembles appendicitis
● If associated with low grade mucinous lesions, may cause pseudomyxoma peritonei (Mod Pathol 2000;13:495)

Gross description
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● Usually < 5 mm

Micro description
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● Herniation of mucosa and muscularis mucosa through wall of the appendix

Micro images
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Diverticulum with cystadenoma

End of Appendix > Diverticulosis

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