Appendix
General
Diverticulosis


Topic Completed: 1 August 2012

Revised: 29 April 2019

Revised: 21 January 2019

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PubMed Search: Diverticulosis appendix

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Cite this page: Mansouri J. Diverticulosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/appendixdiverticula.html. Accessed July 22nd, 2019.
Definition / general
  • Uncommon, in 0.004 - 2% of appendectomies
  • More likely acquired than congenital
  • Usually multiple diverticuli (diverticula) if present
  • Due to increased intraluminal pressure and wall weakness
  • Present in 14% of cystic fibrosis patients versus 1 - 2% of general population (Hum Pathol 1987;18:75)
  • Marker for presence of local/regional neoplasms (J Clin Pathol 2012;65:638)
  • May cause diverticulitis, which clinically resembles appendicitis
  • If associated with low grade mucinous lesions, may cause pseudomyxoma peritonei (Mod Pathol 2000;13:495)
Gross description
  • Usually < 5 mm
Microscopic (histologic) description
  • Herniation of mucosa and muscularis mucosa through wall of the appendix
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