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Benign tumors

Hyperplastic polyp / mucinous hyperplasia

Reviewer: Jaleh Mansouri, M.D., (see Reviewers page)
Revised: 20 October 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

Clinical features

● Resembles colonic hyperplastic polyp
● More common in women, which may reflect higher incidence of incidental appendectomy in women
● Usually age 40+ years
● Associated with adenocarcinoma of right colon, although not precancerous per se

Gross description

● Usually sessile or flat
● May appear as diffuse lesion without well-defined borders

Micro description

● Resembles colonic hyperplastic polyp: columnar and goblet cell proliferation with elongated and dilated tubules
● Luminal outlines are serrated
● Minimal hyperchromasia and no stratification

Differential diagnosis

● Villous adenoma (dysplastic nuclei), serrated polyp with abnormal proliferation/sessile serrated polyp/sessile serrated adenoma (Am J Clin Pathol 2010;133:623)

End of Appendix > Benign tumors > Hyperplastic polyp / mucinous hyperplasia

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