Topic Completed: 1 August 2012

Revised: 20 August 2019

Copyright: (c) 2003-2019,, Inc.

PubMed Search: Malakoplakia appendix

Page views in 2018: 216
Page views in 2019 to date: 196
Cite this page: Mansouri J. Malakoplakia. website. Accessed December 8th, 2019.
Definition / general
  • Unusual in appendix (< 10 cases reported); commonly involves bladder
  • At all sites, associated with tumors (lymphoma, colonic tumors), infections (TB, fungi), sarcoidosis, immunocompromise (malnutrition, diabetes, alcoholic liver disease, steroids)
Case reports
Microscopic (histologic) description
  • Infiltrate of large granular eosinophilic macrophages with concentrically laminated siderocalcific Michaelis-Gutmann (MG) bodies
Microscopic (histologic) images

Images hosted on other servers:

Various images

Electron microscopy description
  • Concentric crystalline laminations with dense inner zone containing partially digested bacteria and thin outer zone
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