Table of ContentsDefinition / General | Case Reports | Micro Description | Micro Images | Electron Microscopy Description
Cite this page: Malakoplakia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/appendixmalakoplakia.html. Accessed December 5th, 2016.
Definition / General
- Unusual in appendix (< 10 cases reported); commonly involves bladder
- At all sites, associated with tumors (lymphoma, colonic tumors), infections (TB, fungi), sarcoidosis, immunocompromise (malnutrition, diabetes, alcoholic liver disease, steroids)
- Infiltrate of large granular eosinophilic macrophages with concentrically laminated siderocalcific Michaelis-Gutmann (MG) bodies
Electron Microscopy Description
- Concentric crystalline laminations with dense inner zone containing partially digested bacteria and thin outer zone