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Appendix

Appendicitis

Malakoplakia


Reviewer: Jaleh Mansouri, M.D. (see Reviewers page)
Revised: 21 October 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Unusual in appendix (< 10 cases reported); commonly involves bladder
● At all sites, associated with tumors (lymphoma, colonic tumors), infections (TB, fungi), sarcoidosis, immunocompromise (malnutrition, diabetes, alcoholic liver disease, steroids)

Case reports
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● 60 year old man with mass composed of eggs of Taenia (tapeworm) species (Arch Pathol Lab Med 2000;124:1828)
● 61 year old man with long standing ulcerative colitis (J Med Case Rep 2008 May 29;2:181)

Micro description
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● Infiltrate of large granular eosinophilic macrophages with concentrically laminated siderocalcific Michaelis-Gutmann (MG) bodies

Micro images
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Various images

Electron microscopy description
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● Concentric crystalline laminations with dense inner zone containing partially digested bacteria and thin outer zone

End of Appendix > Appendicitis > Malakoplakia


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