Reviewer: Jaleh Mansouri, M.D. (see Authors page)

Revised: 16 February 2016, last major update August 2012

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Malakoplakia appendix
Cite this page: Malakoplakia. website. Accessed May 21st, 2018.
Definition / general
  • Unusual in appendix (< 10 cases reported); commonly involves bladder
  • At all sites, associated with tumors (lymphoma, colonic tumors), infections (TB, fungi), sarcoidosis, immunocompromise (malnutrition, diabetes, alcoholic liver disease, steroids)
Case reports
Microscopic (histologic) description
  • Infiltrate of large granular eosinophilic macrophages with concentrically laminated siderocalcific Michaelis-Gutmann (MG) bodies
Microscopic (histologic) images

Images hosted on other servers:

Various images

Electron microscopy description
  • Concentric crystalline laminations with dense inner zone containing partially digested bacteria and thin outer zone