Signet ring cell adenocarcinoma
Reviewer: Jaleh Mansouri, M.D. (see Reviewers page)
Revised: 21 October 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.
● Rare tumor in appendix with poor prognosis
● May occur with goblet cell carcinoid
● Stage using TNM, based on depth of malignant epithelioid cells, not depth of dissecting mucus
● 67 year old woman (World J Gastroenterol 2008;14:5763)
● Right hemicolectomy, remove mucus and peritoneal implants carefully
● Debulk if recurrent disease
● Resembles similar tumor elsewhere in GI tract
● Goblet cell carcinoid: arises from glandular mucosa, spares luminal mucosa, insular pattern, no desmoplasia, better prognosis
End of Appendix > Carcinoma > Signet ring cell adenocarcinoma
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