Signet ring cell adenocarcinoma

Reviewer: Jaleh Mansouri, M.D. (see Authors page)

Revised: 29 February 2016, last major update August 2012

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Signet ring cell adenocarcinoma
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Cite this page: Signet ring cell adenocarcinoma. website. Accessed January 20th, 2019.
Definition / general
  • Rare tumor in appendix with poor prognosis
  • May occur with goblet cell carcinoid
  • Stage using TNM, based on depth of malignant epithelioid cells, not depth of dissecting mucus
  • Case reports
  • Right hemicolectomy, remove mucus and peritoneal implants carefully
  • Debulk if recurrent disease
  • Microscopic (histologic) description
  • Resembles similar tumor elsewhere in GI tract
  • Microscopic (histologic) images

    Images hosted on other servers:

    Various images

    Differential diagnosis
  • Goblet cell carcinoid: arises from glandular mucosa, spares luminal mucosa, insular pattern, no desmoplasia, better prognosis