Appendix
Carcinoma
Signet ring cell adenocarcinoma


Topic Completed: 1 August 2012

Revised: 21 August 2019

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PubMed Search: Signet ring cell adenocarcinoma

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Cite this page: Mansouri J. Signet ring cell adenocarcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/appendixsignetringcell.html. Accessed August 25th, 2019.
Definition / general
  • Rare tumor in appendix with poor prognosis
  • May occur with goblet cell carcinoid
  • Stage using TNM, based on depth of malignant epithelioid cells, not depth of dissecting mucus
Case reports
Treatment
  • Right hemicolectomy, remove mucus and peritoneal implants carefully
  • Debulk if recurrent disease
Microscopic (histologic) description
  • Resembles similar tumor elsewhere in GI tract
Microscopic (histologic) images

Images hosted on other servers:

Various images

Differential diagnosis
  • Goblet cell carcinoid: arises from glandular mucosa, spares luminal mucosa, insular pattern, no desmoplasia, better prognosis
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