Yersinia granulomatous appendicitis

Reviewer: Jaleh Mansouri, M.D. (see Authors page)

Revised: 16 February 2016, last major update August 2012

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Yersinia granulomatous appendicitis
Cite this page: Yersinia granulomatous appendicitis. website. Accessed May 21st, 2018.
Definition / general
  • Detected in 25% (10 of 40) cases of granulomatous appendicitis by PCR, either Y. enterocolitica or Y. pseudotuberculosis (Am J Surg Pathol 2001;25:508)
  • Some patients may develop Crohn’s disease
  • Histology similar to non-Yersinia granulomatous appendicitis (differentiate by PCR)
Microscopic (histologic) description
  • Epithelioid granulomas with lymphoid cuffing, transmural inflammation with lymphoid aggregates, mucosal ulceration, cryptitis, usually no bacteria identified