Yersinia granulomatous appendicitis

Topic Completed: 1 August 2012

Revised: 20 August 2019

Copyright: (c) 2003-2019,, Inc.

PubMed Search: Yersinia granulomatous appendicitis

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Cite this page: Mansouri J. Yersinia granulomatous appendicitis. website. Accessed December 13th, 2019.
Definition / general
  • Detected in 25% (10 of 40) cases of granulomatous appendicitis by PCR, either Y. enterocolitica or Y. pseudotuberculosis (Am J Surg Pathol 2001;25:508)
  • Some patients may develop Crohn’s disease
  • Histology similar to non-Yersinia granulomatous appendicitis (differentiate by PCR)
Microscopic (histologic) description
  • Epithelioid granulomas with lymphoid cuffing, transmural inflammation with lymphoid aggregates, mucosal ulceration, cryptitis, usually no bacteria identified
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