Bladder
Acquired nonneoplastic anomalies
Endosalpingiosis



Topic Completed: 01 July 2011

Revised: 14 December 2018

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Endosalpingiosis
Cite this page: Chaux A Endosalpingiosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/bladderendosalpingiosis.html. Accessed December 15th, 2018.
Definition / general
  • Involvement of lamina propria and muscularis propria by tubules and cysts with tubal type epithelium (ciliated cells, intercalated cells, peg cells)
Terminology
  • Called Müllerianosis if two of three related entities (endocervicosis, endometriosis or endosalpingiosis) are present (Mod Pathol 1996;9:731)
Epidemiology
  • Very uncommon
  • Usually seen in women of childbearing age
Sites
  • Posterior wall or posterior dome
Etiology
  • Metaplastic (Müllerian metaplasia) or implantative (similar to endometriosis)
Clinical features
  • Suprapubic pain, urinary frequency, dysuria
  • May occur after surgery in some cases
Case reports
Treatment
Gross description
  • May form mass on posterior wall of bladder
Microscopic (histologic) description
  • Involvement of lamina propria and muscularis propria by tubules and cysts of Müllerian type epithelium
  • May replace urothelium and form polypoid projections into bladder lumen
  • Tubules and cysts are round / oval, may have prominent branching
  • Glands are lined by tubal type epithelium (ciliated cells, intercalated cells, peg cells)
  • No atypia, no mitotic figures, no necrosis
Microscopic (histologic) images

Ovary: glands lined by ciliated epithelium lie in fibrous stroma

Ovary: ciliated,
secretory and
intercalated cells
line the cystic space

Differential diagnosis
  • Adenocarcinoma: marked atypia, invasive borders, usually not ciliated and lacks 3 types of tubal cells