Bladder
Acquired non-neoplastic anomalies
Endosalpingiosis

Author: Alcides Chaux, M.D. (see Authors page)

Revised: 16 March 2016, last major update July 2011

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: Endosalpingiosis
Cite this page: Endosalpingiosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/bladderendosalpingiosis.html. Accessed December 8th, 2016.
Definition / General
  • Involvement of lamina propria and muscularis propria by tubules and cysts with tubal-type epithelium (ciliated cells, intercalated cells, peg cells)
Terminology
  • Called mullerianosis if two of three related entities (endocervicosis, endometriosis or endosalpingiosis) are present (Mod Pathol 1996;9:731)
Epidemiology
  • Very uncommon
  • Usually seen in women of childbearing age
Sites
  • Posterior wall or posterior dome
Etiology
  • Metaplastic (mullerian metaplasia) or implantative (similar to endometriosis)
Clinical Features
  • Suprapubic pain, urinary frequency, dysuria
  • May occur after surgery in some cases
Case Reports
Treatment
Gross Description
  • May form mass on posterior wall of bladder
Micro Description
  • Involvement of lamina propria and muscularis propria by tubules and cysts of mullerian-type epithelium
  • May replace urothelium and form polypoid projections into bladder lumen
  • Tubules and cysts are round/oval, may have prominent branching
  • Glands are lined by tubal type epithelium (ciliated cells, intercalated cells, peg cells)
  • No atypia, no mitotic figures, no necrosis
Micro Images

Images hosted on Pathout server:

Ovary: glands lined by ciliated epithelium lie in fibrous stroma


Ovary: ciliated, secretory and intercalated cells line the cystic space



Images hosted on other servers:

Ovary: glands lined by tubal type epithelium

Differential Diagnosis
  • Adenocarcinoma: marked atypia, invasive borders, usually not ciliated and lacks 3 types of tubal cells