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Bladder
Other tumors
Germ cell tumor
Author: Nat Pernick, M.D. (see Authors page)
Revised: 27 December 2009, last major update - December 2009
Copyright: (c) 2002-2009, PathologyOutlines.com, Inc.
Definition
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● Includes choriocarcinoma, dermoid cyst, seminoma, teratoma, yolk sac tumors
Terminology
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Epidemiology
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Sites
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Etiology
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Clinical features
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Prognostic factors
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Case reports
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● 7 month old male infant with rapidly enlarging intra-abdominal tumor (Archives 2002;126:1106)
● 37 year old man with choriocarcinoma of bladder and no known testicular primary (Clin Oncol (R Coll Radiol) 1996;8:59)
● 44 year old woman with dermoid cyst arising from bladder dome (Clin Exp Obstet Gynecol 2008;35:309)
● 81 year old man with choriocarcinoma of bladder (Pathol Int 2005;55:216)
Treatment
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Clinical images
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Gross description (Macroscopy)
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Gross images
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Micro description (Histopathology)
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Micro images
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Cytology description
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● Seminoma: loosely cohesive cell clusters of highly atypical large cells and occasional large, single cells with macronucleoli; background of mainly lymphocytes and histiocytes (Diagn Cytopathol 2008;36:734)
Cytology images
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Positive stains
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Negative stains
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Electron microscopy descriptions
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Electron microscopy images
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Molecular / cytogenetics description
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Molecular / cytogenetics images
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Differential Diagnosis
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● Metastases or extension of germ cell tumor from adjacent site
● Urothelial carcinomas with choriocarcinomatous differentiation (Hum Pathol 1984;15:793, Cancer 1993;71:3972)
Additional references
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End of Bladder > Other tumors > Germ cell tumor
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