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Benign tumors

Post-operative granulomas

Reviewer: Monika Roychowdhury, M.D., University of Minnesota Medical Center (see Reviewers page)
Revised: 3 July 2011, last major update April 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.


● Reactive lesion that occurs after catheterization or diathermy (Acta Pathol Jpn 1986;36:1813)
● Foreign body granulomas may occur post-bladder neck suspension (Int Urol Nephrol 2001;33:351) or other surgery (Am J Clin Path 1986;86:430)


● May be due to metals deposited during diathermy, local reaction to tissue necrosis or hypersensitivity reaction (Urology 1990;35:454)
● Includes “starch” granulomas (Urology 1976;8:507)

Micro description

● Palisading histiocytes or giant cells surrounding central necrosis (resembling rheumatoid nodules) or foreign body type granuloma
● Lesions heal by fibrous scarring

Micro images


Differential diagnosis

Granulomatous cystitis: terms may overlap; often refers to patients with infectious etiology and no distinct mass

End of Bladder > Benign tumors > Post-operative granulomas

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