Bladder
Other tumors
Urachal sarcoma

Author: Gillian Levy, M.D. (see Authors page)

Revised: 9 August 2016, last major update December 2014

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: Bladder urachal sarcoma
Definition / General
  • Criteria for diagnosis: sarcoma that occurs at a site consistent with anatomical position of urachus; tumor must demonstrate relationship with urachus
Epidemiology
  • Usually < age 20 years
Sites
  • At dome of bladder or superior / anterior wall of bladder
Etiology
  • Urachal ligament is embryologic remnant connecting the dome of the bladder to the umbilicus; urachal remnant may persist and contain tubular or cystic structures (see patent urachus)
Clinical Features
  • Mesenchymal lesions are rare in urachus
  • Leiomyosarcomas or rhabdomyosarcomas are most common urachal sarcomas; represent 8% of urachal malignancies
  • Sarcomas present with hematuria and cystic or solid structure in the bladder dome
  • Propensity for distant metastasis is low, but can have local recurrence
Case Reports
Treatment
  • Partial cystectomy and en bloc resection of the urachal ligament with the umbilicus
  • No standard chemotherapy/radiation regimen
Micro Description
  • Variable, depends on the subtype of sarcoma
Micro Images

Images hosted on other servers:
Missing Image

Urachal MFH – various images

Positive Stains
Negative Stains
Differential Diagnosis
  • Sarcomas of non-urachal origin: predominantly ages 40-59