Bladder & ureters
Other tumors
Urachal sarcoma


Topic Completed: 1 December 2014

Revised: 27 June 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Bladder urachal sarcoma

Page views in 2018: 292
Page views in 2019 to date: 232
Cite this page: Levy G. Urachal sarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/bladderurachalsarcoma.html. Accessed August 18th, 2019.
Definition / general
  • Criteria for diagnosis: sarcoma that occurs at a site consistent with anatomical position of urachus; tumor must demonstrate relationship with urachus
Epidemiology
  • Usually < age 20 years
Sites
  • At dome of bladder or superior / anterior wall of bladder
Etiology
  • Urachal ligament is embryologic remnant connecting the dome of the bladder to the umbilicus; urachal remnant may persist and contain tubular or cystic structures (see patent urachus)
Clinical features
  • Mesenchymal lesions are rare in urachus
  • Leiomyosarcomas or rhabdomyosarcomas are most common urachal sarcomas; represent 8% of urachal malignancies
  • Sarcomas present with hematuria and cystic or solid structure in the bladder dome
  • Propensity for distant metastasis is low, but can have local recurrence
Case reports
Treatment
  • Partial cystectomy and en bloc resection of the urachal ligament with the umbilicus
  • No standard chemotherapy/radiation regimen
Microscopic (histologic) description
  • Variable, depends on the subtype of sarcoma
Microscopic (histologic) images

Images hosted on other servers:
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Urachal MFH - various images

Positive stains
Negative stains
Differential diagnosis
  • Sarcomas of non-urachal origin: predominantly ages 40-59
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