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Table of Contents
Definition / general | Radiology description | Case reports | Treatment | Microscopic (histologic) description | Microscopic (histologic) images | Cytology description | Differential diagnosis | Additional referencesCite this page: Benign fibrous histiocytoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/boneBFH.html. Accessed July 14th, 2017.
Definition / general
- Very uncommon
- Usually older than 20 years
- Associated with pain
- Benign behavior
- Sites: pelvic bones, other unusual sites
Radiology description
- Small, lytic lesions with sharply defined margins and a sclerotic rim
Case reports
- 45 year old man with painful shoulder lesion composed of xanthomatous material (Arch Pathol Lab Med 2002;126:599)
Treatment
- Curettage and bone grafting, may recur locally
Microscopic (histologic) description
- Storiform pattern of spindled cells with frequent foam cells and variable benign multinucleated giant cells
- Resembles cutaneous counterpart
Microscopic (histologic) images
Images hosted on PathOut server:
Foam cells with delicate fibrous stroma and reactive bone
Cytology description
- Scattered foam cells, minimal inflammatory infiltrate, no mitotic activity
Differential diagnosis
- Fibrous cortical defect
- Giant cell tumor of bone
- Low grade fibrosarcoma
- Metaphyseal fibrous defect / nonossifying fibroma: similar histology but characteristic radiologic findings, usually younger than age 20 years, metaphysis of long bones
- Xanthoma
Additional references
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