Other tumors of bone
Benign fibrous histiocytoma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 27 October 2016, last major update June 2005

Copyright: (c) 2003-2016,, Inc.

PubMed search: benign fibrous histiocytoma [title] bone

Cite this page: Benign fibrous histiocytoma. website. Accessed March 22nd, 2018.
Definition / general
  • Very uncommon
  • Usually older than 20 years
  • Associated with pain
  • Benign behavior
  • Sites: pelvic bones, other unusual sites
Radiology description
  • Small, lytic lesions with sharply defined margins and a sclerotic rim
Case reports
  • Curettage and bone grafting, may recur locally
Microscopic (histologic) description
  • Storiform pattern of spindled cells with frequent foam cells and variable benign multinucleated giant cells
  • Resembles cutaneous counterpart
Microscopic (histologic) images
Images hosted on PathOut server:

Foam cells with delicate fibrous stroma and reactive bone

Cytology description
  • Scattered foam cells, minimal inflammatory infiltrate, no mitotic activity
Differential diagnosis
Additional references