Bone
Other tumors of bone
Leiomyosarcoma

Author: Nat Pernick, M.D.

Revised: 16 October 2018, last major update June 2005

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed search: leiomyosarcoma [title] bone

Cite this page: Pernick, N. Leiomyosarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/boneLMS.html. Accessed December 15th, 2018.
Definition / general
  • Very rare as primary tumor of bone, resembles soft tissue counterpart
  • Mean age 44 years, range 13 - 77 years; no gender preference
  • Often jaw, femur or other long bones
  • May occur postradiation therapy
  • 75% high grade, predicts recurrence and metastases
Microscopic (histologic) images
Images hosted on other servers:

Quiz case

Positive stains
Negative stains
  • p53 (usually)
Electron microscopy description
  • Cytoplasmic microfilaments with focal densities
Differential diagnosis