Bone
Other tumors of bone
Leiomyosarcoma




Topic Completed: 1 June 2005

Revised: 3 January 2019

Copyright: (c) 2003-2019, PathologyOutlines.com, Inc.

PubMed search: leiomyosarcoma [title] bone



Nat Pernick, M.D.
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Cite this page: Pernick N Leiomyosarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/boneLMS.html. Accessed June 19th, 2019.
Definition / general
  • Very rare as primary tumor of bone, resembles soft tissue counterpart
  • Mean age 44 years, range 13 - 77 years; no gender preference
  • Often jaw, femur or other long bones
  • May occur postradiation therapy
  • 75% high grade, predicts recurrence and metastases
Microscopic (histologic) images
Images hosted on other servers:

Quiz case

Positive stains
Negative stains
  • p53 (usually)
Electron microscopy description
  • Cytoplasmic microfilaments with focal densities
Differential diagnosis
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