Other tumors of bone

Author: Nat Pernick, M.D. (see Authors page)

Revised: 18 October 2016, last major update June 2005

Copyright: (c) 2003-2016,, Inc.

PubMed search: leiomyosarcoma [title] bone

Cite this page: Leiomyosarcoma. website. Accessed October 28th, 2016.
Definition / General
  • Very rare as primary tumor of bone, resembles soft tissue counterpart
  • Mean age 44 years, range 13 - 77 years; no gender preference
  • Often jaw, femur or other long bones
  • May occur post radiation therapy
  • 75% high grade, predicts recurrence and metastases
Micro Images
Images hosted on other servers:

Quiz case

Positive Stains
Negative Stains
  • p53 (usually)
Electron Microscopy Description
  • Cytoplasmic microfilaments with focal densities
Differential Diagnosis