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Bone
Other tumors of bone
Leiomyosarcoma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 18 October 2016, last major update June 2005

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PubMed search: leiomyosarcoma [title] bone

Table of Contents
Definition / general | Microscopic (histologic) images | Positive stains | Negative stains | Electron microscopy description | Differential diagnosis | Additional references
Cite this page: Leiomyosarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/boneLMS.html. Accessed July 14th, 2017.
Definition / general
  • Very rare as primary tumor of bone, resembles soft tissue counterpart
  • Mean age 44 years, range 13 - 77 years; no gender preference
  • Often jaw, femur or other long bones
  • May occur post radiation therapy
  • 75% high grade, predicts recurrence and metastases
Microscopic (histologic) images
Images hosted on other servers:

Quiz case

Positive stains
Negative stains
  • p53 (usually)
Electron microscopy description
  • Cytoplasmic microfilaments with focal densities
Differential diagnosis
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