Reviewers: Dariusz Borys, M.D. (see Reviewers page)
Revised: 8 June 2012, last major update June 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.
● Usually young adults or children
● Involvement of spine (thoracic/lumbar)
● Extensive necrosis of intervertebral discs with extension into soft tissue
● May produce significant deformities or neurologic deficits
● Difficult to treat
● In US, due to immigrants and immunosuppression
● 1-3% with tuberculosis have bone infection, usually from focus of acute visceral disease, direct extension or lymphatics
● Rarely causes inguinal mass with fluctuant psoas abscess
● In AIDS patients, bone infection usually multifocal
● Advanced cases are associated with cutaneous sinuses, which cause secondary bacterial infections
● Associated with fusion of joint, denudation of cartilage, sequestra of medullary cavity
● Can detect in synovial fluid by culture and examination
● Vertebrae, hip, knee, ankle, elbow, wrist
● Usually involves synovium, epiphysis or metaphysis
● Foreign body granuloma post-surgery
(Am J Surg Pathol 1997;21:563)
End of Bone > Osteomyelitis > Tuberculous osteomyelitis
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).