Bone
Osteomyelitis
Tuberculous osteomyelitis



Topic Completed: 1 August 2013

Revised: 27 December 2018

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Tuberculous osteomyelitis[title]
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Cite this page: Borys D Tuberculous osteomyelitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/boneTBosteo.html. Accessed February 15th, 2019.
Definition / general
  • Usually young adults or children

Pott's disease:
  • Involvement of spine (thoracic / lumbar)
  • Extensive necrosis of intervertebral discs with extension into soft tissue
  • May produce significant deformities or neurologic deficits
  • Difficult to treat
Clinical features
  • In US, due to immigrants and immunosuppression
  • 1 - 3% with tuberculosis have bone infection, usually from focus of acute visceral disease, direct extension or lymphatics
  • Rarely causes inguinal mass with fluctuant psoas abscess
  • In AIDS patients, bone infection usually multifocal
  • Advanced cases are associated with cutaneous sinuses, which cause secondary bacterial infections
  • Associated with fusion of joint, denudation of cartilage, sequestra of medullary cavity
  • Can detect in synovial fluid by culture and examination
Sites
  • Vertebrae, hip, knee, ankle, elbow, wrist
  • Usually involves synovium, epiphysis or metaphysis
Radiology images

Contributed by Dr. Mark R. Wick
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Cervical vertebrae paraspinal tuberculous abscess MRI

Gross images

Contributed by Dr. Mark R. Wick
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Tubeculous vertebral osteomyelitis (Pott disease)

Microscopic (histologic) images

Contributed by Dr. Mark R. Wick
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Differential diagnosis