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Reviewers: Dariusz Borys, M.D. (see Reviewers page)
Revised: 1 June 2012, last major update June 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.


Frozen sections:
● Useful to document adequacy of tissue
● Allows quicker definitive treatment (if diagnosis can be made)
● Assessment of tumor margins
● Useful to obtain culture for possible infectious lesions
● Useful to differentiate between aseptic and infectious inflammation for implant replacement

FNA (Fine Needle Aspiration):
● Helpful for identifying metastatic disease (Arch Pathol Lab Med 2001;125:1463), recurrent tumor or unsuspected malignancy
● Not helpful for cartilaginous lesions, cystic lesions or obviously benign lesions that require surgical management (chondromyxoid fibroma, giant cell tumor)

End of Bone > Biopsy

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