Bone & joints

Topic Completed: 1 June 2012

Revised: 26 December 2018

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Bone biopsy[title]

Dariusz Borys, M.D.
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Table of Contents
Definition / general
Cite this page: Borys D Biopsy. website. Accessed October 28th, 2020.
Definition / general
    Frozen sections:
    • Useful to document adequacy of tissue
    • Allows quicker definitive treatment (if diagnosis can be made)
    • Assessment of tumor margins
    • Useful to obtain culture for possible infectious lesions
    • Useful to differentiate between aseptic and infectious inflammation for implant replacement

    FNA (Fine Needle Aspiration):
    • Helpful for identifying metastatic disease (Arch Pathol Lab Med 2001;125:1463), recurrent tumor or unsuspected malignancy
    • Not helpful for cartilaginous lesions, cystic lesions or obviously benign lesions that require surgical management (chondromyxoid fibroma, giant cell tumor)
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