Chemotherapy effect

Author: Nat Pernick, M.D. (see Authors page)

Revised: 23 November 2016, last major update August 2013

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Bone chemotherapy effect[title]
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Cite this page: Chemotherapy effect. website. Accessed December 18th, 2018.
Definition / general
  • Report extent of necrosis in resected osteosarcomas (recommended to take one slide of entire tumor, decalcify and embed)
  • Consider cells viable if in doubt
Microscopic (histologic) description
  • Fibrosis, granulation tissue, frank necrosis, dense bone formation within marrow cavity